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The map label for this gene is sppA [C]

Identifier: 150399145

GI number: 150399145

Start: 447325

End: 448260

Strand: Reverse

Name: sppA [C]

Synonym: Mevan_0392

Alternate gene names: 150399145

Gene position: 448260-447325 (Counterclockwise)

Preceding gene: 150399146

Following gene: 150399144

Centisome position: 26.06

GC content: 33.23

Gene sequence:

>936_bases
ATGAAAAAAGTTTATACCTATTCAGCAGCTGCATTTGTTATTATGGGGCTATTATTGATTGGGATTTTGGCAGTTGTATC
TTTTGATACGTCCTTTTCAAATAATATTGCAATGATAAATTTAGATGGTGCTATCTTTTTAAAAGGTAGTGATTCAGGAT
TATTAAGCACTGGAACGACGGGTGTTGAAGATTATATAAAATGGCTTGATGAAGTTGAAAATAATGATAATATAAAAGCA
GTTATCATTAAAATTAATTCTCCTGGAGGGGAAGTTGTTGCAAGTGAAAAACTTTCAAGAAAAATTAAAGAAGTTTCCGA
AAAAAAGCCAGTTGTGGCATACATCGAAACAATTGGGGCTTCAGGCGCATACATGGCGGCATCATCATCAAATTATATCG
TTGCAGAAAAACAATCCCTTGTTGGAAGTATAGGGGTTAGAATGGAATTATTGCACTATTATGGCCTCATGGAAAAACTG
GGCGTAAATACAACAAGTATAACCGGTGGAAAGTATAAAAACATTGGAACGCCAAATAGGCCAATGACTGAAGAAGAATA
TAAAATGCTTGAATCAATTGTTGATGAAATGTACTTTGATTTTATTTCAATGGTTGCAGAAAATAGGAACATGACAATAA
ATGAAACATTGATTGCGGCTGACGGAAAAATTTATAACGGGTTACAGGCTAAAAATGCAGGCCTCATAGACCAAGTTGGA
ACTGAAAAAGATGCAATTGATATGGCATGTAAATTTGCAAAAATATCCGAACCAAGAATCTATGAATACAAAAAAAGTAG
TTCTATCGGGTTTTTTGGCATGACGCTTAATAATATCGCAACAAGTTTTGGATACGGGTTTGGAAAAGGAATTTCTGAAA
ACATGGATATAAAAGAAAGTTTTAAATCTTATAAGTCGTATGAAATGTACTATTAA

Upstream 100 bases:

>100_bases
CTGAACTTGACAACATACTTTCAGAACTAAAAGAAGATGGGGAAATTTACGAACCAAATTCTGGAAGTTATAGAATACTC
TAATTTAAGGGGGCTTAGAA

Downstream 100 bases:

>100_bases
AGATTTATAATACCTTATTCTTTTTTATGGTGAAAATATGCTTTTTGAATCAGTGCTTTTTTTAGCATTGGGTTTATTGA
TGCTGTCATATGGTAGTGAC

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKKVYTYSAAAFVIMGLLLIGILAVVSFDTSFSNNIAMINLDGAIFLKGSDSGLLSTGTTGVEDYIKWLDEVENNDNIKA
VIIKINSPGGEVVASEKLSRKIKEVSEKKPVVAYIETIGASGAYMAASSSNYIVAEKQSLVGSIGVRMELLHYYGLMEKL
GVNTTSITGGKYKNIGTPNRPMTEEEYKMLESIVDEMYFDFISMVAENRNMTINETLIAADGKIYNGLQAKNAGLIDQVG
TEKDAIDMACKFAKISEPRIYEYKKSSSIGFFGMTLNNIATSFGYGFGKGISENMDIKESFKSYKSYEMYY

Sequences:

>Translated_311_residues
MKKVYTYSAAAFVIMGLLLIGILAVVSFDTSFSNNIAMINLDGAIFLKGSDSGLLSTGTTGVEDYIKWLDEVENNDNIKA
VIIKINSPGGEVVASEKLSRKIKEVSEKKPVVAYIETIGASGAYMAASSSNYIVAEKQSLVGSIGVRMELLHYYGLMEKL
GVNTTSITGGKYKNIGTPNRPMTEEEYKMLESIVDEMYFDFISMVAENRNMTINETLIAADGKIYNGLQAKNAGLIDQVG
TEKDAIDMACKFAKISEPRIYEYKKSSSIGFFGMTLNNIATSFGYGFGKGISENMDIKESFKSYKSYEMYY
>Mature_311_residues
MKKVYTYSAAAFVIMGLLLIGILAVVSFDTSFSNNIAMINLDGAIFLKGSDSGLLSTGTTGVEDYIKWLDEVENNDNIKA
VIIKINSPGGEVVASEKLSRKIKEVSEKKPVVAYIETIGASGAYMAASSSNYIVAEKQSLVGSIGVRMELLHYYGLMEKL
GVNTTSITGGKYKNIGTPNRPMTEEEYKMLESIVDEMYFDFISMVAENRNMTINETLIAADGKIYNGLQAKNAGLIDQVG
TEKDAIDMACKFAKISEPRIYEYKKSSSIGFFGMTLNNIATSFGYGFGKGISENMDIKESFKSYKSYEMYY

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=250, Percent_Identity=27.2, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787527, Length=168, Percent_Identity=26.7857142857143, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34184; Mature: 34184

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYTYSAAAFVIMGLLLIGILAVVSFDTSFSNNIAMINLDGAIFLKGSDSGLLSTGTT
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCEECCCC
GVEDYIKWLDEVENNDNIKAVIIKINSPGGEVVASEKLSRKIKEVSEKKPVVAYIETIGA
CHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEEEHHCC
SGAYMAASSSNYIVAEKQSLVGSIGVRMELLHYYGLMEKLGVNTTSITGGKYKNIGTPNR
CCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
PMTEEEYKMLESIVDEMYFDFISMVAENRNMTINETLIAADGKIYNGLQAKNAGLIDQVG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHCC
TEKDAIDMACKFAKISEPRIYEYKKSSSIGFFGMTLNNIATSFGYGFGKGISENMDIKES
CCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCHHHH
FKSYKSYEMYY
HHHHHCCCCCC
>Mature Secondary Structure
MKKVYTYSAAAFVIMGLLLIGILAVVSFDTSFSNNIAMINLDGAIFLKGSDSGLLSTGTT
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCEECCCC
GVEDYIKWLDEVENNDNIKAVIIKINSPGGEVVASEKLSRKIKEVSEKKPVVAYIETIGA
CHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEEEHHCC
SGAYMAASSSNYIVAEKQSLVGSIGVRMELLHYYGLMEKLGVNTTSITGGKYKNIGTPNR
CCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
PMTEEEYKMLESIVDEMYFDFISMVAENRNMTINETLIAADGKIYNGLQAKNAGLIDQVG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHCC
TEKDAIDMACKFAKISEPRIYEYKKSSSIGFFGMTLNNIATSFGYGFGKGISENMDIKES
CCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCHHHH
FKSYKSYEMYY
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]