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The map label for this gene is glpC [C]

Identifier: 150399143

GI number: 150399143

Start: 444639

End: 446123

Strand: Reverse

Name: glpC [C]

Synonym: Mevan_0390

Alternate gene names: 150399143

Gene position: 446123-444639 (Counterclockwise)

Preceding gene: 150399144

Following gene: 150399141

Centisome position: 25.94

GC content: 32.59

Gene sequence:

>1485_bases
GTGAACACAGTTAAAATAAACGTGAAAAAAACCGAAGGATTTAAAGAATTTATTGTACCTGAAAAAATAACTGTAACTGA
CGCTTTAGAATATATTAATAAAAATTACGGCGAAAATATACAGTTTAGGGTATCCTGTAGGGCAGGCCAATGTGGGAGCT
GTGCAATGACAATAAATAAAAAATCAAGGCTTGCATGTAAGACAAAAGTTGAAGATAAAATGTATATTGAGCCCTTAGAT
GGATTTGACGTTATTATTGACCTCGTAGTTGATAGAAGTCCGTACTATAAAAAACTAGGAACATTGAAAAATTACATTCA
GCAAAAAAACGGTAAACCTAACCTTGAAGAACTATCAAATTTAAAGATATATCCTAACGATATTAAAGATGTTAAATCGA
TTAGAGGATGCATTGAATGTTTAAGCTGTATTTCAATGTGTCCTGCGAGAAAATATTCTAATTATCCTGGGCCTACATTT
ATGAGACAGCTTGCAAGGTTTGCTTTTGACAAAAGAGATGATTCAAAACGGGAAAGCGATGCATTTAACGAAAATATTTA
TAACTGTACAACTTGCGGTAGATGTGTTGAAGTCTGTCCAAAAGAAATCGATATTGTACATAATGTAGTTGAAAAATTAA
GGGAAAAGACATTTAAAAAAGGATACAATCTTGAAAGCCATTTAGAAGTTAGAAAAAACGCATTACTCCAAAAAAGGTCA
ATTCCAAAAGATAAATCTTCATTTTTAGAGGAAGTAAAAGATGAATATTTTGTAGAAAATGAAAAATTGCGTGTTGCATT
TTTTACAGGATGTTTGGTCGATTTTAGACTTTTAGAACTTGGAAAAAGTGCAGTAAGGGTTTTAAATGCACATGGTGTTT
CAGTAGTAATTCCAAAGTTACAGGTATGTTGCGGTTCCCCATACATTAGAACTGGTCAGACGGATATCTCAGAAATGTTA
AAAAAACAAAACCTCGAAATTTTTAATAAGTTAAATGTTGACTATGTTGTTACTCTTTGTGCAGGGTGCGGAAGCACTTT
AAAGAATGATTACAAAGAAAAAGAGTTTAAGATAAAGGATATTACTGAAATTTTAACAGAAGTTGGATTAATTGAGTATA
AGCCTTTAGATATTACAGTAACTTACCACGACCCATGCCACTTGAGACGAGGTCAAAAAGTATATCTTGAACCTAGGAAA
ATTTTAGAAAGCATTCCAAAATTAAAATTTGTTGAAATGGAAATTCCCGACCAGTGCTGCGGTGCAGGAGGGGGAGTTCG
TTCTGGAAAGCCAGAAGTTGCAGCTTTAATCGGGAAAAGAAAAGCAAATATGGTATATAAAACAGATGCAGATTATGTAA
TTACGGTATGCCCATTTTGCGAATATCACGTTAGGGACAGCTTGAAAAAATACATGGAAGAAAACAGTTTTAAAAAAGAA
ATTCCTGTAATGAATATAGTTTCACTACTTGATAAAGTGATTTAA

Upstream 100 bases:

>100_bases
CTTAATATGCCATTTTTATATACTACCTTAATATAATTTAATCTAGATTCAAATTTATTAATTTATTATTTTTTTTATCT
GAATTTCAGGGTTGATACGT

Downstream 100 bases:

>100_bases
GAATTATCTACTTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATT
ATTATTTAATTTCCTTTAGT

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MNTVKINVKKTEGFKEFIVPEKITVTDALEYINKNYGENIQFRVSCRAGQCGSCAMTINKKSRLACKTKVEDKMYIEPLD
GFDVIIDLVVDRSPYYKKLGTLKNYIQQKNGKPNLEELSNLKIYPNDIKDVKSIRGCIECLSCISMCPARKYSNYPGPTF
MRQLARFAFDKRDDSKRESDAFNENIYNCTTCGRCVEVCPKEIDIVHNVVEKLREKTFKKGYNLESHLEVRKNALLQKRS
IPKDKSSFLEEVKDEYFVENEKLRVAFFTGCLVDFRLLELGKSAVRVLNAHGVSVVIPKLQVCCGSPYIRTGQTDISEML
KKQNLEIFNKLNVDYVVTLCAGCGSTLKNDYKEKEFKIKDITEILTEVGLIEYKPLDITVTYHDPCHLRRGQKVYLEPRK
ILESIPKLKFVEMEIPDQCCGAGGGVRSGKPEVAALIGKRKANMVYKTDADYVITVCPFCEYHVRDSLKKYMEENSFKKE
IPVMNIVSLLDKVI

Sequences:

>Translated_494_residues
MNTVKINVKKTEGFKEFIVPEKITVTDALEYINKNYGENIQFRVSCRAGQCGSCAMTINKKSRLACKTKVEDKMYIEPLD
GFDVIIDLVVDRSPYYKKLGTLKNYIQQKNGKPNLEELSNLKIYPNDIKDVKSIRGCIECLSCISMCPARKYSNYPGPTF
MRQLARFAFDKRDDSKRESDAFNENIYNCTTCGRCVEVCPKEIDIVHNVVEKLREKTFKKGYNLESHLEVRKNALLQKRS
IPKDKSSFLEEVKDEYFVENEKLRVAFFTGCLVDFRLLELGKSAVRVLNAHGVSVVIPKLQVCCGSPYIRTGQTDISEML
KKQNLEIFNKLNVDYVVTLCAGCGSTLKNDYKEKEFKIKDITEILTEVGLIEYKPLDITVTYHDPCHLRRGQKVYLEPRK
ILESIPKLKFVEMEIPDQCCGAGGGVRSGKPEVAALIGKRKANMVYKTDADYVITVCPFCEYHVRDSLKKYMEENSFKKE
IPVMNIVSLLDKVI
>Mature_494_residues
MNTVKINVKKTEGFKEFIVPEKITVTDALEYINKNYGENIQFRVSCRAGQCGSCAMTINKKSRLACKTKVEDKMYIEPLD
GFDVIIDLVVDRSPYYKKLGTLKNYIQQKNGKPNLEELSNLKIYPNDIKDVKSIRGCIECLSCISMCPARKYSNYPGPTF
MRQLARFAFDKRDDSKRESDAFNENIYNCTTCGRCVEVCPKEIDIVHNVVEKLREKTFKKGYNLESHLEVRKNALLQKRS
IPKDKSSFLEEVKDEYFVENEKLRVAFFTGCLVDFRLLELGKSAVRVLNAHGVSVVIPKLQVCCGSPYIRTGQTDISEML
KKQNLEIFNKLNVDYVVTLCAGCGSTLKNDYKEKEFKIKDITEILTEVGLIEYKPLDITVTYHDPCHLRRGQKVYLEPRK
ILESIPKLKFVEMEIPDQCCGAGGGVRSGKPEVAALIGKRKANMVYKTDADYVITVCPFCEYHVRDSLKKYMEENSFKKE
IPVMNIVSLLDKVI

Specific function: Electron Transfer Protein; May Also Function As The Membrane Anchor For The Glpab Dimer. [C]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=201, Percent_Identity=32.3383084577114, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788576, Length=386, Percent_Identity=25.6476683937824, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790596, Length=207, Percent_Identity=31.4009661835749, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786943, Length=195, Percent_Identity=32.8205128205128, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI48994913, Length=398, Percent_Identity=22.8643216080402, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786497, Length=244, Percent_Identity=23.7704918032787, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17533915, Length=198, Percent_Identity=30.8080808080808, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322987, Length=204, Percent_Identity=30.3921568627451, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643156, Length=199, Percent_Identity=29.6482412060301, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137106, Length=201, Percent_Identity=30.8457711442786, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR004017
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: PF02754 CCG; PF00111 Fer2 [H]

EC number: 1.3.99.1

Molecular weight: Translated: 56495; Mature: 56495

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVKINVKKTEGFKEFIVPEKITVTDALEYINKNYGENIQFRVSCRAGQCGSCAMTINK
CCEEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECC
KSRLACKTKVEDKMYIEPLDGFDVIIDLVVDRSPYYKKLGTLKNYIQQKNGKPNLEELSN
CCHHEEHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHCC
LKIYPNDIKDVKSIRGCIECLSCISMCPARKYSNYPGPTFMRQLARFAFDKRDDSKRESD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
AFNENIYNCTTCGRCVEVCPKEIDIVHNVVEKLREKTFKKGYNLESHLEVRKNALLQKRS
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
IPKDKSSFLEEVKDEYFVENEKLRVAFFTGCLVDFRLLELGKSAVRVLNAHGVSVVIPKL
CCCHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCEEEECHH
QVCCGSPYIRTGQTDISEMLKKQNLEIFNKLNVDYVVTLCAGCGSTLKNDYKEKEFKIKD
HHHCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ITEILTEVGLIEYKPLDITVTYHDPCHLRRGQKVYLEPRKILESIPKLKFVEMEIPDQCC
HHHHHHHCCCEEECCEEEEEEECCCHHHCCCCEEEECHHHHHHHCCCEEEEEEECCHHHH
GAGGGVRSGKPEVAALIGKRKANMVYKTDADYVITVCPFCEYHVRDSLKKYMEENSFKKE
CCCCCCCCCCCHHHHHHHHHHCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHH
IPVMNIVSLLDKVI
CCHHHHHHHHHHHC
>Mature Secondary Structure
MNTVKINVKKTEGFKEFIVPEKITVTDALEYINKNYGENIQFRVSCRAGQCGSCAMTINK
CCEEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECC
KSRLACKTKVEDKMYIEPLDGFDVIIDLVVDRSPYYKKLGTLKNYIQQKNGKPNLEELSN
CCHHEEHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHCC
LKIYPNDIKDVKSIRGCIECLSCISMCPARKYSNYPGPTFMRQLARFAFDKRDDSKRESD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
AFNENIYNCTTCGRCVEVCPKEIDIVHNVVEKLREKTFKKGYNLESHLEVRKNALLQKRS
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
IPKDKSSFLEEVKDEYFVENEKLRVAFFTGCLVDFRLLELGKSAVRVLNAHGVSVVIPKL
CCCHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCEEEECHH
QVCCGSPYIRTGQTDISEMLKKQNLEIFNKLNVDYVVTLCAGCGSTLKNDYKEKEFKIKD
HHHCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ITEILTEVGLIEYKPLDITVTYHDPCHLRRGQKVYLEPRKILESIPKLKFVEMEIPDQCC
HHHHHHHCCCEEECCEEEEEEECCCHHHCCCCEEEECHHHHHHHCCCEEEEEEECCHHHH
GAGGGVRSGKPEVAALIGKRKANMVYKTDADYVITVCPFCEYHVRDSLKKYMEENSFKKE
CCCCCCCCCCCHHHHHHHHHHCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHH
IPVMNIVSLLDKVI
CCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA