Click here to switch to the map view.

The map label for this gene is hdrB2 [H]

Identifier: 150399130

GI number: 150399130

Start: 430937

End: 431818

Strand: Reverse

Name: hdrB2 [H]

Synonym: Mevan_0376

Alternate gene names: 150399130

Gene position: 431818-430937 (Counterclockwise)

Preceding gene: 150399131

Following gene: 150399128

Centisome position: 25.1

GC content: 38.1

Gene sequence:

>882_bases
ATGAAATACGCGTTTTTCCTTGGATGTATTATGCCAAACAGGTACGCTGGTGTGGAATCTGCTACAAGAACAGTAATGGA
GAAATTAGGTGTTGAATTAGTAGATATGCCTGGAGCTTCCTGCTGTCCGGCTCCGGGAGTATTTGGTTCATTCGACCAAA
AAACATGGTTAACTTTAGCTGCAAGAAACTTGTGTATTGCAGAAGAAATGGGCGTAGATATAGTTACCGTATGTAACGGA
TGTTATGGTTCATTATTTGAAGCTGCACACATGTTACATGAAAACAAAGATGCTTTAAAAATGGTAAACGAACAGCTTAA
CGAAGTTGGAAAAGAATATAAAGGAACCGTTCATGTAAGGCACTTTGCTGAATTAATCTACAATGACATAGGTGTAGATA
AAATTAGAGAAAACGTTGTAAAACCATTAAGTGTAAATATAGGCGTTCACTACGGGTGCCACTTCTTAAAACCAACATCT
GCAAAAGGACTCGGCAGTGCTGAAAATCCAACAATGCTTGATGAACTTGTTGAAGCAACCGGTGCTAAGTCAGTAGCATA
TAAAGATAAAATGATGTGTTGTGGTGCAGGTGGTGGTGTAAGGGCTAAAGAATTAGATCTTGCATTAAGTATGACTCAGG
AAAAAATTGAAAACATGTTGGCAGTGGGTGCTGATGCTACTGTTAACGTATGTCCATTCTGTCAGTTGCAATTTGACAGG
GGGCAAATTGAAATTAAAGAAAAACTCGGTAACGAATATGGATTCCCAGTTGTACATTTATCCCAACTTTTAGGTCTTGC
AATGGGAATGAAGCCATCAGAAGTTGCTTTAGATGTAAACTTTATTTCGCCAGAACCGTTACTTAATAAATTAGGATACT
AA

Upstream 100 bases:

>100_bases
AGTGTTTGAAATTTGATGATTTAATAGGATTTGACTGGAAAACAATGGGTTTAAAACAATAATTTAAGATATAGTCTAAA
TTTAAAAAATGGTGATATTG

Downstream 100 bases:

>100_bases
TCCATTTAATTTTAATTCTATTTTTTTAAATAAAAATAATAAATAGTTATTATACTGTAATTTATTCAAATTCGCTTAAA
TCAATGTTTTTTGAAGCATC

Product: CoB--CoM heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGVDIVTVCNG
CYGSLFEAAHMLHENKDALKMVNEQLNEVGKEYKGTVHVRHFAELIYNDIGVDKIRENVVKPLSVNIGVHYGCHFLKPTS
AKGLGSAENPTMLDELVEATGAKSVAYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDR
GQIEIKEKLGNEYGFPVVHLSQLLGLAMGMKPSEVALDVNFISPEPLLNKLGY

Sequences:

>Translated_293_residues
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGVDIVTVCNG
CYGSLFEAAHMLHENKDALKMVNEQLNEVGKEYKGTVHVRHFAELIYNDIGVDKIRENVVKPLSVNIGVHYGCHFLKPTS
AKGLGSAENPTMLDELVEATGAKSVAYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDR
GQIEIKEKLGNEYGFPVVHLSQLLGLAMGMKPSEVALDVNFISPEPLLNKLGY
>Mature_293_residues
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGVDIVTVCNG
CYGSLFEAAHMLHENKDALKMVNEQLNEVGKEYKGTVHVRHFAELIYNDIGVDKIRENVVKPLSVNIGVHYGCHFLKPTS
AKGLGSAENPTMLDELVEATGAKSVAYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDR
GQIEIKEKLGNEYGFPVVHLSQLLGLAMGMKPSEVALDVNFISPEPLLNKLGY

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction [H]

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017678
- InterPro:   IPR004017 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 31852; Mature: 31852

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLA
CCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ARNLCIAEEMGVDIVTVCNGCYGSLFEAAHMLHENKDALKMVNEQLNEVGKEYKGTVHVR
HHHHHHHHHHCCEEEEHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
HFAELIYNDIGVDKIRENVVKPLSVNIGVHYGCHFLKPTSAKGLGSAENPTMLDELVEAT
HHHHHHHHHCCHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCCCCCCCCHHHHHHHHHC
GAKSVAYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDR
CCCHHHECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECC
GQIEIKEKLGNEYGFPVVHLSQLLGLAMGMKPSEVALDVNFISPEPLLNKLGY
CCEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHCCC
>Mature Secondary Structure
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLA
CCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ARNLCIAEEMGVDIVTVCNGCYGSLFEAAHMLHENKDALKMVNEQLNEVGKEYKGTVHVR
HHHHHHHHHHCCEEEEHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
HFAELIYNDIGVDKIRENVVKPLSVNIGVHYGCHFLKPTSAKGLGSAENPTMLDELVEAT
HHHHHHHHHCCHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCCCCCCCCHHHHHHHHHC
GAKSVAYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDR
CCCHHHECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECC
GQIEIKEKLGNEYGFPVVHLSQLLGLAMGMKPSEVALDVNFISPEPLLNKLGY
CCEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]