Click here to switch to the map view.

The map label for this gene is bepR [H]

Identifier: 150398586

GI number: 150398586

Start: 3602662

End: 3603330

Strand: Reverse

Name: bepR [H]

Synonym: Smed_3397

Alternate gene names: 150398586

Gene position: 3603330-3602662 (Counterclockwise)

Preceding gene: 150398587

Following gene: 150398583

Centisome position: 95.28

GC content: 63.83

Gene sequence:

>669_bases
ATGCGCCGAACCAAGGCCGACGCCGAGGCTACAAGACAGAAGATCCTGTGCGCCGCCGAACGCATGTTCTTTAAAAAGGG
CGTCCCCAACACGACGCTTGAGGAAGTGGCCAAGGAGGCGGGCGTCACCCGCGGCGCCATATACTGGCATTTCGCCAACA
AGACGGATCTCTTCCTCGCCCTTTACGAGGCCGTGCCGCTGCCCCACGAAGACATGATCGCGCGCGAGATCGAAACGGAA
GCCTTCGACACGCTCGCCATCGTCGAAAGCGCGACCAGCGACTGGCTGACGACGCTGGCCGCAGACGAGCAGCGGCAGCG
CATTCTCGCGATCATGCTGCGCTGCGACTACGACAATGACATGTCCGCCGTGCTCGTCCGCCAGCGCGAAATCGAGGAGC
GCCATGATGCGTTGCTCGAACTTGCCTTCGCCCGCGCGCTCGCCCGCGGCCAGATGCAGGAACACTGGACGCCTCCGTCG
GCAACGCGGGCCCTGCGCTGGATGATGATGGGGCTGTGTACCGAATGGCTTCTCTTCGGCCGCAGATTCGATCTGGTGAT
CGAAGGGCGCGAGGCGCTCCACCGCCTCTTTGCCAGCTTCCGGCAGGAGGCGGCGGCACCACAAAACCTCGCAACCATCG
GCGATGAGAGTGCCCCTCACCGGAGATGA

Upstream 100 bases:

>100_bases
GCCAAGCAGGCATCCGAAACCGTCAGCCCCGCCGAGTGATCGGAGAAGATGGCCCGCCGGCTTACAGCGGCGGGCCATCT
GTTAAGGAGAATTGGAATAA

Downstream 100 bases:

>100_bases
GGATAACTTTGCGGGATGCGGCCGGGACGCCACGCGCATCAAACCTCAACGCTTACCGCGCCGGTAGCGGATCGTGTTGA
ACTGCGCGGCAAGCGCATCG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRRTKADAEATRQKILCAAERMFFKKGVPNTTLEEVAKEAGVTRGAIYWHFANKTDLFLALYEAVPLPHEDMIAREIETE
AFDTLAIVESATSDWLTTLAADEQRQRILAIMLRCDYDNDMSAVLVRQREIEERHDALLELAFARALARGQMQEHWTPPS
ATRALRWMMMGLCTEWLLFGRRFDLVIEGREALHRLFASFRQEAAAPQNLATIGDESAPHRR

Sequences:

>Translated_222_residues
MRRTKADAEATRQKILCAAERMFFKKGVPNTTLEEVAKEAGVTRGAIYWHFANKTDLFLALYEAVPLPHEDMIAREIETE
AFDTLAIVESATSDWLTTLAADEQRQRILAIMLRCDYDNDMSAVLVRQREIEERHDALLELAFARALARGQMQEHWTPPS
ATRALRWMMMGLCTEWLLFGRRFDLVIEGREALHRLFASFRQEAAAPQNLATIGDESAPHRR
>Mature_222_residues
MRRTKADAEATRQKILCAAERMFFKKGVPNTTLEEVAKEAGVTRGAIYWHFANKTDLFLALYEAVPLPHEDMIAREIETE
AFDTLAIVESATSDWLTTLAADEQRQRILAIMLRCDYDNDMSAVLVRQREIEERHDALLELAFARALARGQMQEHWTPPS
ATRALRWMMMGLCTEWLLFGRRFDLVIEGREALHRLFASFRQEAAAPQNLATIGDESAPHRR

Specific function: Represses expression of bepDE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=194, Percent_Identity=32.4742268041237, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789664, Length=127, Percent_Identity=37.007874015748, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25449; Mature: 25449

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTKADAEATRQKILCAAERMFFKKGVPNTTLEEVAKEAGVTRGAIYWHFANKTDLFLA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHH
LYEAVPLPHEDMIAREIETEAFDTLAIVESATSDWLTTLAADEQRQRILAIMLRCDYDND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
MSAVLVRQREIEERHDALLELAFARALARGQMQEHWTPPSATRALRWMMMGLCTEWLLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
RRFDLVIEGREALHRLFASFRQEAAAPQNLATIGDESAPHRR
CHHHEEECCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MRRTKADAEATRQKILCAAERMFFKKGVPNTTLEEVAKEAGVTRGAIYWHFANKTDLFLA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHH
LYEAVPLPHEDMIAREIETEAFDTLAIVESATSDWLTTLAADEQRQRILAIMLRCDYDND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
MSAVLVRQREIEERHDALLELAFARALARGQMQEHWTPPSATRALRWMMMGLCTEWLLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
RRFDLVIEGREALHRLFASFRQEAAAPQNLATIGDESAPHRR
CHHHEEECCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]