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The map label for this gene is glcD [H]

Identifier: 150398350

GI number: 150398350

Start: 3316895

End: 3318316

Strand: Direct

Name: glcD [H]

Synonym: Smed_3158

Alternate gene names: 150398350

Gene position: 3316895-3318316 (Clockwise)

Preceding gene: 150398349

Following gene: 150398351

Centisome position: 87.7

GC content: 64.14

Gene sequence:

>1422_bases
ATGATTGACGAGCACCATATCGACGCACTGGAGAAGCTCCTTGGCGACAAGGGCATCGTCACGGGCCGGGAGGACATGGA
AGCTTATGAGACCGGCGCGCGCTATGACCGCGGCCGCGCGGCCGCCGTACTGCGTCCCGCCACCACCGAAGAAGCTTCCG
CCGCCGTCGGCTACTGCGTCCGCAACGGCATTGCGCTCGTTCCGCAGGCGGGCAATACCGGCCTCGTATCGGGATCGACG
CCGGACGGGTCGGGCGAGGAGGTCGTCCTCAGCCTGGACCGGCTGACCCGCCGGTTCGCGCTCGACCCCGACAATCGCTC
GGTACGCGTCGACGCCGGTTTCCGCCTGTCCGAACTCAACCGGCGGCTGGAGGAATATGAGCTGTTCTTCCCGATCGACC
TCGGCGCCGACCCGCGGATCGGCGGCATGGTCGCGACCAATACGGGCGGCTCGCGCTTTCTCAAATATGGCGACGTCCGC
CGCAATATACTGGGCCTGAAGGTGGTACTCGCCGATGAGGCGGGCACCGTACTGGACCTCCACTCGGACCTGCGCAAGAA
CAATACCGGGGTCGACTGGAAGCAGATCTTCATCGGCACGTCCGGCGCCTTCGGGATCGTCACCGAATGCGTGCTCAATC
TCGAGCGCCTGCCGAAGCAGACGGCGACTGCCTTCCTGGTACCGGCAAGCGGCGCACATGTGCTGCCTCTCCTGAAAGCC
ATGGAAGAGCGGCTCGGCGCCTATCTCTCGGCCTTCGAGGGCATGTCGAAGAACGCGATCGCCGGGGCTCTCGCCCATGT
GCCGTCGCTCAAGAACCCGTTCCCGGGCGGCAACGTCCCCGAATACGTCATCCTCGCGGAAATCTCCCGGAGCTGGGCGC
CGCGCGACGGCGAACAGCCACTCGATGCGGTGCTCGAAAGCGTACTTGCAGAGATATGGGAAACGGAGGAAGCGCCGCTC
GCAGACGCGCTCGTCGGCCCGCCGCATGAAGTCTGGGCGCTGCGCCACGCCCTTTCGGAAGGCGTGAAGCACCTCGGCAA
GCTGATCGCCTTCGACCTCTCCTTCCGCAGGGGTGACATCATGACCTTCTGTGATCATATGAAGGCCGAAATGCCGCAGA
AATTTCCTGCTGTCACAATCTGCGACTTCGGCCATATCGGCGACGGCGGTGTCCACTTCAACGTCGTGGTTGCGAAGGAC
AGTCCGCTTCTGGCCGATGCGGCCTTCGAGCAGCACCTGCGCGAATGGGTCGTCGCGATCGCCGTCGAGCAATATCATGG
CAGCTTCAGCGCCGAACATGCGCTCGGCCGCCGCAATCAGGCCTTTTACGATTTCTACACGCCGGAAAAACTGAAGAACA
TCGCCGCCGGCCTCAAGACGCTCACCTCGCCGGGAAAGCTCGGCAGCGTGCGTTTCGGGTAG

Upstream 100 bases:

>100_bases
CTCAACGAATTCGATCACTATGCCGGCATCGAACAGGCATCGATCGAAGACTGCCTCCAGGCGCTCACCGCCGCCGTGGC
AGCGGAGTGATACGTCGCCA

Downstream 100 bases:

>100_bases
GCGGCCGAAAGAAACGGGAGTCAAGTGACATGAACATTGCAGCCAAGAAGGTCGACGTTGCAAAGGAGGCTGCGGCTCTC
CTTGAGAAGATGGGCGTCGC

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MIDEHHIDALEKLLGDKGIVTGREDMEAYETGARYDRGRAAAVLRPATTEEASAAVGYCVRNGIALVPQAGNTGLVSGST
PDGSGEEVVLSLDRLTRRFALDPDNRSVRVDAGFRLSELNRRLEEYELFFPIDLGADPRIGGMVATNTGGSRFLKYGDVR
RNILGLKVVLADEAGTVLDLHSDLRKNNTGVDWKQIFIGTSGAFGIVTECVLNLERLPKQTATAFLVPASGAHVLPLLKA
MEERLGAYLSAFEGMSKNAIAGALAHVPSLKNPFPGGNVPEYVILAEISRSWAPRDGEQPLDAVLESVLAEIWETEEAPL
ADALVGPPHEVWALRHALSEGVKHLGKLIAFDLSFRRGDIMTFCDHMKAEMPQKFPAVTICDFGHIGDGGVHFNVVVAKD
SPLLADAAFEQHLREWVVAIAVEQYHGSFSAEHALGRRNQAFYDFYTPEKLKNIAAGLKTLTSPGKLGSVRFG

Sequences:

>Translated_473_residues
MIDEHHIDALEKLLGDKGIVTGREDMEAYETGARYDRGRAAAVLRPATTEEASAAVGYCVRNGIALVPQAGNTGLVSGST
PDGSGEEVVLSLDRLTRRFALDPDNRSVRVDAGFRLSELNRRLEEYELFFPIDLGADPRIGGMVATNTGGSRFLKYGDVR
RNILGLKVVLADEAGTVLDLHSDLRKNNTGVDWKQIFIGTSGAFGIVTECVLNLERLPKQTATAFLVPASGAHVLPLLKA
MEERLGAYLSAFEGMSKNAIAGALAHVPSLKNPFPGGNVPEYVILAEISRSWAPRDGEQPLDAVLESVLAEIWETEEAPL
ADALVGPPHEVWALRHALSEGVKHLGKLIAFDLSFRRGDIMTFCDHMKAEMPQKFPAVTICDFGHIGDGGVHFNVVVAKD
SPLLADAAFEQHLREWVVAIAVEQYHGSFSAEHALGRRNQAFYDFYTPEKLKNIAAGLKTLTSPGKLGSVRFG
>Mature_473_residues
MIDEHHIDALEKLLGDKGIVTGREDMEAYETGARYDRGRAAAVLRPATTEEASAAVGYCVRNGIALVPQAGNTGLVSGST
PDGSGEEVVLSLDRLTRRFALDPDNRSVRVDAGFRLSELNRRLEEYELFFPIDLGADPRIGGMVATNTGGSRFLKYGDVR
RNILGLKVVLADEAGTVLDLHSDLRKNNTGVDWKQIFIGTSGAFGIVTECVLNLERLPKQTATAFLVPASGAHVLPLLKA
MEERLGAYLSAFEGMSKNAIAGALAHVPSLKNPFPGGNVPEYVILAEISRSWAPRDGEQPLDAVLESVLAEIWETEEAPL
ADALVGPPHEVWALRHALSEGVKHLGKLIAFDLSFRRGDIMTFCDHMKAEMPQKFPAVTICDFGHIGDGGVHFNVVVAKD
SPLLADAAFEQHLREWVVAIAVEQYHGSFSAEHALGRRNQAFYDFYTPEKLKNIAAGLKTLTSPGKLGSVRFG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=468, Percent_Identity=35.2564102564103, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI37595756, Length=186, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI37595754, Length=245, Percent_Identity=28.1632653061224, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789351, Length=459, Percent_Identity=25.2723311546841, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534361, Length=462, Percent_Identity=32.6839826839827, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI71992373, Length=222, Percent_Identity=30.1801801801802, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71992381, Length=222, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71992392, Length=104, Percent_Identity=37.5, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320023, Length=463, Percent_Identity=31.9654427645788, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320764, Length=415, Percent_Identity=30.6024096385542, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320027, Length=228, Percent_Identity=28.0701754385965, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI18921117, Length=437, Percent_Identity=32.4942791762014, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24639277, Length=437, Percent_Identity=32.4942791762014, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24639275, Length=437, Percent_Identity=32.4942791762014, Blast_Score=192, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51307; Mature: 51307

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEHHIDALEKLLGDKGIVTGREDMEAYETGARYDRGRAAAVLRPATTEEASAAVGYCV
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
RNGIALVPQAGNTGLVSGSTPDGSGEEVVLSLDRLTRRFALDPDNRSVRVDAGFRLSELN
HCCEEEEECCCCCCEECCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCCHHHHH
RRLEEYELFFPIDLGADPRIGGMVATNTGGSRFLKYGDVRRNILGLKVVLADEAGTVLDL
HHHHHCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHEEEEEEEECCCCCEEEC
HSDLRKNNTGVDWKQIFIGTSGAFGIVTECVLNLERLPKQTATAFLVPASGAHVLPLLKA
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHCCEEEEECCCCHHHHHHHH
MEERLGAYLSAFEGMSKNAIAGALAHVPSLKNPFPGGNVPEYVILAEISRSWAPRDGEQP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCH
LDAVLESVLAEIWETEEAPLADALVGPPHEVWALRHALSEGVKHLGKLIAFDLSFRRGDI
HHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MTFCDHMKAEMPQKFPAVTICDFGHIGDGGVHFNVVVAKDSPLLADAAFEQHLREWVVAI
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
AVEQYHGSFSAEHALGRRNQAFYDFYTPEKLKNIAAGLKTLTSPGKLGSVRFG
HHHHHCCCCCHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIDEHHIDALEKLLGDKGIVTGREDMEAYETGARYDRGRAAAVLRPATTEEASAAVGYCV
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
RNGIALVPQAGNTGLVSGSTPDGSGEEVVLSLDRLTRRFALDPDNRSVRVDAGFRLSELN
HCCEEEEECCCCCCEECCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCCHHHHH
RRLEEYELFFPIDLGADPRIGGMVATNTGGSRFLKYGDVRRNILGLKVVLADEAGTVLDL
HHHHHCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHEEEEEEEECCCCCEEEC
HSDLRKNNTGVDWKQIFIGTSGAFGIVTECVLNLERLPKQTATAFLVPASGAHVLPLLKA
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHCCEEEEECCCCHHHHHHHH
MEERLGAYLSAFEGMSKNAIAGALAHVPSLKNPFPGGNVPEYVILAEISRSWAPRDGEQP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCH
LDAVLESVLAEIWETEEAPLADALVGPPHEVWALRHALSEGVKHLGKLIAFDLSFRRGDI
HHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MTFCDHMKAEMPQKFPAVTICDFGHIGDGGVHFNVVVAKDSPLLADAAFEQHLREWVVAI
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
AVEQYHGSFSAEHALGRRNQAFYDFYTPEKLKNIAAGLKTLTSPGKLGSVRFG
HHHHHCCCCCHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]