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The map label for this gene is xylB [H]

Identifier: 150398229

GI number: 150398229

Start: 3183314

End: 3184822

Strand: Reverse

Name: xylB [H]

Synonym: Smed_3035

Alternate gene names: 150398229

Gene position: 3184822-3183314 (Counterclockwise)

Preceding gene: 150398230

Following gene: 150398228

Centisome position: 84.21

GC content: 63.62

Gene sequence:

>1509_bases
ATGGGCTATTTTCTGACCGCGGATGGCGGCACCGAAAGTCTTCGGGCACGCCTTTACGATCTCACCGGCAACTGCCTCGG
GAGCGCTGCCGTCCCTTACGAGACGAGGTTTTCGGCCGGCGCGCGCGCCGAACAGAACCCGGAGGATTGGTGGAGAGCCT
TCGTCGAAGCATCGCGCCGGACGATCTCGGAGGCAGACGTGGAACCGGCTGCAATCGAGGCGATCACGCTTGCGACGACG
AGTTGCACAGTGGTCGCGCTCGACCGTGAGGGCAAGGCGCTCAGGCCGGCGATCATCTGGATGGATGTGCGCGCCAGCGA
TGAAGCGGACGCGGTTCTCGCAACCGGCGACGAAGCCCTCATTTCAAACGGGGCCGGTCGTGGACCGGTGTCAGCGGAAT
GGATGATCCCGAAGGCATTGTGGATCGCCCGCAACGAACCCGAGATATTCGAAGAAGCACACACGATCTGCGAATACCAG
GACTTCATGACCTTGAGGCTCACCGGGGAGCGTGCGGCGAGCCTCAACAACGTGACGCTACGATGGCACTACCAGACCGA
TCGCGGCGGCTGGGCCAGGACGCTCGTAGAGAAGCTCGGACTTTCGGCGCTGCTCGACAAATGGCCCCAGCGAGTCGTCG
CCCCAGGTGAAGTCGTAGGTACCCTATCGCCGGCTGCCGCACAGGAACTCGGTCTCTCCACCAGGGTCAAGCTGGTCCAA
GGCGGCGCGGATGCCCTGATCGGCATGATCGGGCTGGGCGTCGCCAAACCCGGGCAGCTCGCGTTGATCACCGGCTCGTC
GCATCTTCAGTTCGGCGTCACGGAATCCGCCGTTCATGCACCGGGTGTTTGGGGCACTTATCGTGACTGCGTTTATCCGA
ACCGCTACATCGTCGAAGGGGGCCAGACTTCCACCGGATCGATCATCGCCTGGCTCGGCCGGCTGATGAACGGGACGATG
GATCTCGACGAACTGAACCGCAAGGCGGCCGCGCTCGAGCCCGGTTGCGACGGGCTTCTGGTACAGGACCATTTCCAGGG
GAACCGAACTCCCTACACCGATGCGCTCTCGCGCGGCGCGATCGTCGGTCTGACACTGGCCCACGAGCCGCATCATATCT
TTCGCGCCATCATGGAGGGCATAGGCTTCGGGACGCGCGCAATTCTCGATGCCATGGCGGAAGCAGGCTATCGCGGCAGC
GAAATCACAGTTGGCGGAGGTGCTGGCGCATCCGAGCTCTGGCTTCAGATTCATGCCGATACCGCCGGTCTTCCGGTGTG
CGTGCCGGCCTCCCGCGATGCGCCGTCCGTAGGTGCCGCGGTTCTTGCCGCGCATGGCGCCGGCTATTTCGCCAGCATCG
ACGAGGGCATTTCAGCGATGGTGCGGCCGGGTAAGCGTATCGAGCCCCGCCCGCGTGAGGCAGCGCTCTACGACGGGATC
TATCAGCAGTACCGCGCGCTCTATCCTGCACTGAAGTCGCTTCGGGATCGGGGAGGTGAACCAAGATGA

Upstream 100 bases:

>100_bases
TGAGCGGCGGTCCGGCGGTCATGTATGGCGCAAAGGCATTGGAAATCATGCGCGCACTGCAATAGGGAGCCATCCCGCAG
GGGCGGAGGAGGAGGATGGA

Downstream 100 bases:

>100_bases
GTGACGCTGACTTCAGGCTGGACGGCAGGCGTGCGGTCGTAACGGGCGCTGCCCGGGGCATCGGCCGGGCGATCGCCGAA
CGGCTGGCTGTGGCCGGTGC

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MGYFLTADGGTESLRARLYDLTGNCLGSAAVPYETRFSAGARAEQNPEDWWRAFVEASRRTISEADVEPAAIEAITLATT
SCTVVALDREGKALRPAIIWMDVRASDEADAVLATGDEALISNGAGRGPVSAEWMIPKALWIARNEPEIFEEAHTICEYQ
DFMTLRLTGERAASLNNVTLRWHYQTDRGGWARTLVEKLGLSALLDKWPQRVVAPGEVVGTLSPAAAQELGLSTRVKLVQ
GGADALIGMIGLGVAKPGQLALITGSSHLQFGVTESAVHAPGVWGTYRDCVYPNRYIVEGGQTSTGSIIAWLGRLMNGTM
DLDELNRKAAALEPGCDGLLVQDHFQGNRTPYTDALSRGAIVGLTLAHEPHHIFRAIMEGIGFGTRAILDAMAEAGYRGS
EITVGGGAGASELWLQIHADTAGLPVCVPASRDAPSVGAAVLAAHGAGYFASIDEGISAMVRPGKRIEPRPREAALYDGI
YQQYRALYPALKSLRDRGGEPR

Sequences:

>Translated_502_residues
MGYFLTADGGTESLRARLYDLTGNCLGSAAVPYETRFSAGARAEQNPEDWWRAFVEASRRTISEADVEPAAIEAITLATT
SCTVVALDREGKALRPAIIWMDVRASDEADAVLATGDEALISNGAGRGPVSAEWMIPKALWIARNEPEIFEEAHTICEYQ
DFMTLRLTGERAASLNNVTLRWHYQTDRGGWARTLVEKLGLSALLDKWPQRVVAPGEVVGTLSPAAAQELGLSTRVKLVQ
GGADALIGMIGLGVAKPGQLALITGSSHLQFGVTESAVHAPGVWGTYRDCVYPNRYIVEGGQTSTGSIIAWLGRLMNGTM
DLDELNRKAAALEPGCDGLLVQDHFQGNRTPYTDALSRGAIVGLTLAHEPHHIFRAIMEGIGFGTRAILDAMAEAGYRGS
EITVGGGAGASELWLQIHADTAGLPVCVPASRDAPSVGAAVLAAHGAGYFASIDEGISAMVRPGKRIEPRPREAALYDGI
YQQYRALYPALKSLRDRGGEPR
>Mature_501_residues
GYFLTADGGTESLRARLYDLTGNCLGSAAVPYETRFSAGARAEQNPEDWWRAFVEASRRTISEADVEPAAIEAITLATTS
CTVVALDREGKALRPAIIWMDVRASDEADAVLATGDEALISNGAGRGPVSAEWMIPKALWIARNEPEIFEEAHTICEYQD
FMTLRLTGERAASLNNVTLRWHYQTDRGGWARTLVEKLGLSALLDKWPQRVVAPGEVVGTLSPAAAQELGLSTRVKLVQG
GADALIGMIGLGVAKPGQLALITGSSHLQFGVTESAVHAPGVWGTYRDCVYPNRYIVEGGQTSTGSIIAWLGRLMNGTMD
LDELNRKAAALEPGCDGLLVQDHFQGNRTPYTDALSRGAIVGLTLAHEPHHIFRAIMEGIGFGTRAILDAMAEAGYRGSE
ITVGGGAGASELWLQIHADTAGLPVCVPASRDAPSVGAAVLAAHGAGYFASIDEGISAMVRPGKRIEPRPREAALYDGIY
QQYRALYPALKSLRDRGGEPR

Specific function: Unknown

COG id: COG1069

COG function: function code C; Ribulose kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=537, Percent_Identity=30.5400372439479, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI164663830, Length=561, Percent_Identity=29.4117647058824, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI189409120, Length=446, Percent_Identity=23.3183856502242, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4504007, Length=446, Percent_Identity=23.3183856502242, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=23.3853006681514, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789987, Length=493, Percent_Identity=26.1663286004057, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787789, Length=520, Percent_Identity=26.7307692307692, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790005, Length=503, Percent_Identity=24.6520874751491, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789138, Length=500, Percent_Identity=22.8, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786249, Length=550, Percent_Identity=25.2727272727273, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=24.9496981891348, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789168, Length=500, Percent_Identity=23.8, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=441, Percent_Identity=24.0362811791383, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320314, Length=520, Percent_Identity=26.5384615384615, Blast_Score=156, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24657106, Length=541, Percent_Identity=27.5415896487985, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24657102, Length=541, Percent_Identity=27.5415896487985, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI21356323, Length=434, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24655555, Length=389, Percent_Identity=25.1928020565553, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24655560, Length=389, Percent_Identity=25.1928020565553, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24655570, Length=389, Percent_Identity=25.1928020565553, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24655574, Length=389, Percent_Identity=25.1928020565553, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24655565, Length=389, Percent_Identity=25.1928020565553, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17864214, Length=480, Percent_Identity=25, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654573, Length=409, Percent_Identity=25.4278728606357, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 53682; Mature: 53551

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYFLTADGGTESLRARLYDLTGNCLGSAAVPYETRFSAGARAEQNPEDWWRAFVEASRR
CCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TISEADVEPAAIEAITLATTSCTVVALDREGKALRPAIIWMDVRASDEADAVLATGDEAL
HHHHCCCCCHHEEEEEEEECCEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCHHH
ISNGAGRGPVSAEWMIPKALWIARNEPEIFEEAHTICEYQDFMTLRLTGERAASLNNVTL
HCCCCCCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCEEE
RWHYQTDRGGWARTLVEKLGLSALLDKWPQRVVAPGEVVGTLSPAAAQELGLSTRVKLVQ
EEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHEECCCHHHHHHCCCCCEEEEEE
GGADALIGMIGLGVAKPGQLALITGSSHLQFGVTESAVHAPGVWGTYRDCVYPNRYIVEG
CCHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCHHCCCCCCCCCCHHHHCCCCCEEEEC
GQTSTGSIIAWLGRLMNGTMDLDELNRKAAALEPGCDGLLVQDHFQGNRTPYTDALSRGA
CCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCC
IVGLTLAHEPHHIFRAIMEGIGFGTRAILDAMAEAGYRGSEITVGGGAGASELWLQIHAD
EEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEC
TAGLPVCVPASRDAPSVGAAVLAAHGAGYFASIDEGISAMVRPGKRIEPRPREAALYDGI
CCCCEEEECCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
YQQYRALYPALKSLRDRGGEPR
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GYFLTADGGTESLRARLYDLTGNCLGSAAVPYETRFSAGARAEQNPEDWWRAFVEASRR
CEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TISEADVEPAAIEAITLATTSCTVVALDREGKALRPAIIWMDVRASDEADAVLATGDEAL
HHHHCCCCCHHEEEEEEEECCEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCHHH
ISNGAGRGPVSAEWMIPKALWIARNEPEIFEEAHTICEYQDFMTLRLTGERAASLNNVTL
HCCCCCCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCEEE
RWHYQTDRGGWARTLVEKLGLSALLDKWPQRVVAPGEVVGTLSPAAAQELGLSTRVKLVQ
EEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHEECCCHHHHHHCCCCCEEEEEE
GGADALIGMIGLGVAKPGQLALITGSSHLQFGVTESAVHAPGVWGTYRDCVYPNRYIVEG
CCHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCHHCCCCCCCCCCHHHHCCCCCEEEEC
GQTSTGSIIAWLGRLMNGTMDLDELNRKAAALEPGCDGLLVQDHFQGNRTPYTDALSRGA
CCCCCCHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCC
IVGLTLAHEPHHIFRAIMEGIGFGTRAILDAMAEAGYRGSEITVGGGAGASELWLQIHAD
EEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEC
TAGLPVCVPASRDAPSVGAAVLAAHGAGYFASIDEGISAMVRPGKRIEPRPREAALYDGI
CCCCEEEECCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
YQQYRALYPALKSLRDRGGEPR
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]