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The map label for this gene is ybiO [H]

Identifier: 150398198

GI number: 150398198

Start: 3150222

End: 3152303

Strand: Direct

Name: ybiO [H]

Synonym: Smed_3001

Alternate gene names: 150398198

Gene position: 3150222-3152303 (Clockwise)

Preceding gene: 150398197

Following gene: 150398199

Centisome position: 83.3

GC content: 61.0

Gene sequence:

>2082_bases
ATGAGTAACGCACTACCCATTCGAATTGGTTTTCTGCTATTGGCCGTCGCTCCAATCCTCTTTTGGATGCTGCTTGGCGT
TTCCTGGGCACAGCAGGCTCCCGTCGGCGTGCCGCCCGAAAAGGCCCAACAGTTTCTCGGTCTGCTCTCTGATCCCGAGG
TGAGGACATGGCTCGAGGGAAAAATTCCTTCAGCTGCGGCGGAACCCCCTGCCGCGTCGCCCGCCGATACGATTTCGAGC
TGGGAGGCAGCCATCCGCGATCGCATCGGTGGGCTTTTGGGCGCAGTTCCCCGCATACCGGAGGAGCTGGCAAGCGGCGC
CGCTGTTGTCTCGCGCGACGTGAACTCGGGAAGGCCCGGGCTTGTGGTCAGCATATTGGCCGTACTGATCGCCGCTGGCC
TGGGCGCCGAGTGGCTGATCCGAAGGGTCTTTGCCCGGGCACGTAAATCCGGCACAATAGAGGAAGCCGGACAGGAGATC
CTGTCGGAGGTCGCTGCCTTGCTGACGTTTGCCTTGGCCAGCATCGGTTCGTTCCTGGTATTCGAATGGCCGCCCTTGCT
GCGTAAGATCATCCTTACGCTGCTTGTAGCCTTAATCGTGTTTCGGGCCGTTCGGGCGATCAGCAAATTTCTGTTTGCCG
TGAGCGGCTCCAACGGCATTGCCGATCAGCCGATGTCAGCTTTGGCAAGCGATGCGGCACCTCGTTTCTGGCTTTGGCGG
ATCAGCCTTGTTGCCGGCTTTCTGCTGTTCGGTTGGGCCATCGTCAGCCTCATGCCGGAGCTGGGTTTTTCCATCGAGGT
GGTTCGGCTCACCGCGTTTCTGGTCGGGTTGGGCATTCTGGCAACCGCGGTCGAAGTCGTCTGGCGGCGCCCCGACAAGC
CGGCTTCACTTGTCGTCAAGTCACTGCTTACCCTCTATCTCGTCGTGCTTTGGTCGGCTTGGGTCATGGGATTGCTGGGA
GTGCTGTGGCTCGGGATCTATTCGCTGCTGTTGCCGGCTCTGGTGCGGGGCGTTGGCGATGTGGCGCAGGCCTTAGCAAC
CAGAGCACAGCGCACCGGGGCCCCCGGCATCGTACTGGGCGTGCTCATCGTCAGGGGTGCCAGGGCAGCGGTGATCGCCG
CCGCGGTCGCATGGCTCGCCTACATCTGGCGCATCAGAGCTGCAGCCCTCGCCGGCAGCGAACCCGGCGCGATCGTGATA
CCTGGATTGCTCAACGGTATTATCGCCCTCTTGGTCGCCGACCTGCTTTGGCAGATGTCAAAGGCATTGATCGCCTATCG
CATGGGACTTGGGCCGAAGGACGGTTCCAACGCCGATGAACTCGCCCGCAGTGGCCGCTTACGGACGCTCTTGCCGATAT
TCCGCAACGTGCTCGCTGTCTTCATCGGCGCCGTCACCGTGCTGACGATCCTGTCCGGGCTGGGCGTACAGATAGCACCC
TTGATCGCGGGGGCGGGTATTTTCGGCGTTGCCATCGGATTCGGATCGCAGACGCTGGTCAAGGACGTACTCAGCGGCGT
TTTCTACATGCTCGACGATGCCTTCCGTGTCGGTGAATACATCCAGAGCGGCAGCTACAAAGGCACGGTCGAATCGTTCA
GCCTGAGGTCGGTCAGGCTTCGGCATCACCGCGGCCCGATCTTCACGGTGCCGTTCGGGGAGTTGGGAGCCGTTCAGAAC
ATGAGCCGCGACTGGGTGATCGACAAGATGACGCTCAACGTCACTTACGATGCCGACGTAGACCTCGCACGGAAGCTCAT
CAAGAAGGTCGGTCAGGAGCTGGCTGCGGATCCGGAGTTCGCGGCAGACACGATTGAGCCCTTGAAAATGCAGGGTGTCG
ACAGCTTCGGCGACTTTGCGATCGTGCTCAGGATGAAGCTGATGACCAAACCGGGCGCGCAGTTCACTATGAAACGGCGG
GCTTTCATGATGATCAAGAAGGCCTTCGATGAGAACGGCATCAGGATCGCGGTTCCAACCGTTCATGTTTCTGGAGGAAG
CGACAACGCCGCCGCCGCGCAGCAAGCGCTGAACATGAGCAAGGCCGCCGAGCTGGCGGCCAAGGCACCTGTCGCCCCCT
AA

Upstream 100 bases:

>100_bases
GAAAAGGCCGACGGATAGAGCGAGAGTTGGCTGCGCGGTCAAGCCGAAACCTCCGATCTTCTGGTCGCGCCGCCTGCCAG
AAACTAGTCCGGAGCGCCCC

Downstream 100 bases:

>100_bases
AGCGTAAAAACGGTGGACTCTCGTAAGTTCGGGAGGGGGCTGGTCCCGCGGCAGCAAGGATCGCGCCTGCGACTTGCGCG
ATGGCGTAGGCGACCACGCT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSNALPIRIGFLLLAVAPILFWMLLGVSWAQQAPVGVPPEKAQQFLGLLSDPEVRTWLEGKIPSAAAEPPAASPADTISS
WEAAIRDRIGGLLGAVPRIPEELASGAAVVSRDVNSGRPGLVVSILAVLIAAGLGAEWLIRRVFARARKSGTIEEAGQEI
LSEVAALLTFALASIGSFLVFEWPPLLRKIILTLLVALIVFRAVRAISKFLFAVSGSNGIADQPMSALASDAAPRFWLWR
ISLVAGFLLFGWAIVSLMPELGFSIEVVRLTAFLVGLGILATAVEVVWRRPDKPASLVVKSLLTLYLVVLWSAWVMGLLG
VLWLGIYSLLLPALVRGVGDVAQALATRAQRTGAPGIVLGVLIVRGARAAVIAAAVAWLAYIWRIRAAALAGSEPGAIVI
PGLLNGIIALLVADLLWQMSKALIAYRMGLGPKDGSNADELARSGRLRTLLPIFRNVLAVFIGAVTVLTILSGLGVQIAP
LIAGAGIFGVAIGFGSQTLVKDVLSGVFYMLDDAFRVGEYIQSGSYKGTVESFSLRSVRLRHHRGPIFTVPFGELGAVQN
MSRDWVIDKMTLNVTYDADVDLARKLIKKVGQELAADPEFAADTIEPLKMQGVDSFGDFAIVLRMKLMTKPGAQFTMKRR
AFMMIKKAFDENGIRIAVPTVHVSGGSDNAAAAQQALNMSKAAELAAKAPVAP

Sequences:

>Translated_693_residues
MSNALPIRIGFLLLAVAPILFWMLLGVSWAQQAPVGVPPEKAQQFLGLLSDPEVRTWLEGKIPSAAAEPPAASPADTISS
WEAAIRDRIGGLLGAVPRIPEELASGAAVVSRDVNSGRPGLVVSILAVLIAAGLGAEWLIRRVFARARKSGTIEEAGQEI
LSEVAALLTFALASIGSFLVFEWPPLLRKIILTLLVALIVFRAVRAISKFLFAVSGSNGIADQPMSALASDAAPRFWLWR
ISLVAGFLLFGWAIVSLMPELGFSIEVVRLTAFLVGLGILATAVEVVWRRPDKPASLVVKSLLTLYLVVLWSAWVMGLLG
VLWLGIYSLLLPALVRGVGDVAQALATRAQRTGAPGIVLGVLIVRGARAAVIAAAVAWLAYIWRIRAAALAGSEPGAIVI
PGLLNGIIALLVADLLWQMSKALIAYRMGLGPKDGSNADELARSGRLRTLLPIFRNVLAVFIGAVTVLTILSGLGVQIAP
LIAGAGIFGVAIGFGSQTLVKDVLSGVFYMLDDAFRVGEYIQSGSYKGTVESFSLRSVRLRHHRGPIFTVPFGELGAVQN
MSRDWVIDKMTLNVTYDADVDLARKLIKKVGQELAADPEFAADTIEPLKMQGVDSFGDFAIVLRMKLMTKPGAQFTMKRR
AFMMIKKAFDENGIRIAVPTVHVSGGSDNAAAAQQALNMSKAAELAAKAPVAP
>Mature_692_residues
SNALPIRIGFLLLAVAPILFWMLLGVSWAQQAPVGVPPEKAQQFLGLLSDPEVRTWLEGKIPSAAAEPPAASPADTISSW
EAAIRDRIGGLLGAVPRIPEELASGAAVVSRDVNSGRPGLVVSILAVLIAAGLGAEWLIRRVFARARKSGTIEEAGQEIL
SEVAALLTFALASIGSFLVFEWPPLLRKIILTLLVALIVFRAVRAISKFLFAVSGSNGIADQPMSALASDAAPRFWLWRI
SLVAGFLLFGWAIVSLMPELGFSIEVVRLTAFLVGLGILATAVEVVWRRPDKPASLVVKSLLTLYLVVLWSAWVMGLLGV
LWLGIYSLLLPALVRGVGDVAQALATRAQRTGAPGIVLGVLIVRGARAAVIAAAVAWLAYIWRIRAAALAGSEPGAIVIP
GLLNGIIALLVADLLWQMSKALIAYRMGLGPKDGSNADELARSGRLRTLLPIFRNVLAVFIGAVTVLTILSGLGVQIAPL
IAGAGIFGVAIGFGSQTLVKDVLSGVFYMLDDAFRVGEYIQSGSYKGTVESFSLRSVRLRHHRGPIFTVPFGELGAVQNM
SRDWVIDKMTLNVTYDADVDLARKLIKKVGQELAADPEFAADTIEPLKMQGVDSFGDFAIVLRMKLMTKPGAQFTMKRRA
FMMIKKAFDENGIRIAVPTVHVSGGSDNAAAAQQALNMSKAAELAAKAPVAP

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=220, Percent_Identity=37.2727272727273, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1789291, Length=204, Percent_Identity=26.9607843137255, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 73774; Mature: 73643

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNALPIRIGFLLLAVAPILFWMLLGVSWAQQAPVGVPPEKAQQFLGLLSDPEVRTWLEG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
KIPSAAAEPPAASPADTISSWEAAIRDRIGGLLGAVPRIPEELASGAAVVSRDVNSGRPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCH
LVVSILAVLIAAGLGAEWLIRRVFARARKSGTIEEAGQEILSEVAALLTFALASIGSFLV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEWPPLLRKIILTLLVALIVFRAVRAISKFLFAVSGSNGIADQPMSALASDAAPRFWLWR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHH
ISLVAGFLLFGWAIVSLMPELGFSIEVVRLTAFLVGLGILATAVEVVWRRPDKPASLVVK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SLLTLYLVVLWSAWVMGLLGVLWLGIYSLLLPALVRGVGDVAQALATRAQRTGAPGIVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLIVRGARAAVIAAAVAWLAYIWRIRAAALAGSEPGAIVIPGLLNGIIALLVADLLWQMS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHH
KALIAYRMGLGPKDGSNADELARSGRLRTLLPIFRNVLAVFIGAVTVLTILSGLGVQIAP
HHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LIAGAGIFGVAIGFGSQTLVKDVLSGVFYMLDDAFRVGEYIQSGSYKGTVESFSLRSVRL
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RHHRGPIFTVPFGELGAVQNMSRDWVIDKMTLNVTYDADVDLARKLIKKVGQELAADPEF
HHCCCCEEEECCHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCH
AADTIEPLKMQGVDSFGDFAIVLRMKLMTKPGAQFTMKRRAFMMIKKAFDENGIRIAVPT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
VHVSGGSDNAAAAQQALNMSKAAELAAKAPVAP
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNALPIRIGFLLLAVAPILFWMLLGVSWAQQAPVGVPPEKAQQFLGLLSDPEVRTWLEG
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
KIPSAAAEPPAASPADTISSWEAAIRDRIGGLLGAVPRIPEELASGAAVVSRDVNSGRPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCH
LVVSILAVLIAAGLGAEWLIRRVFARARKSGTIEEAGQEILSEVAALLTFALASIGSFLV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEWPPLLRKIILTLLVALIVFRAVRAISKFLFAVSGSNGIADQPMSALASDAAPRFWLWR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHH
ISLVAGFLLFGWAIVSLMPELGFSIEVVRLTAFLVGLGILATAVEVVWRRPDKPASLVVK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SLLTLYLVVLWSAWVMGLLGVLWLGIYSLLLPALVRGVGDVAQALATRAQRTGAPGIVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLIVRGARAAVIAAAVAWLAYIWRIRAAALAGSEPGAIVIPGLLNGIIALLVADLLWQMS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHH
KALIAYRMGLGPKDGSNADELARSGRLRTLLPIFRNVLAVFIGAVTVLTILSGLGVQIAP
HHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LIAGAGIFGVAIGFGSQTLVKDVLSGVFYMLDDAFRVGEYIQSGSYKGTVESFSLRSVRL
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RHHRGPIFTVPFGELGAVQNMSRDWVIDKMTLNVTYDADVDLARKLIKKVGQELAADPEF
HHCCCCEEEECCHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCH
AADTIEPLKMQGVDSFGDFAIVLRMKLMTKPGAQFTMKRRAFMMIKKAFDENGIRIAVPT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
VHVSGGSDNAAAAQQALNMSKAAELAAKAPVAP
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]