Click here to switch to the map view.

The map label for this gene is 150398164

Identifier: 150398164

GI number: 150398164

Start: 3113520

End: 3114236

Strand: Direct

Name: 150398164

Synonym: Smed_2967

Alternate gene names: NA

Gene position: 3113520-3114236 (Clockwise)

Preceding gene: 150398163

Following gene: 150398165

Centisome position: 82.33

GC content: 66.95

Gene sequence:

>717_bases
ATGCGCGTGCTCGTGACCCGGCCACGCCCGTCAGCCGAAAGCACGGCGGCAAAGCTCGGTGCCATGGGCCATGAGACGGC
CATACTGCCGATGTTGCAGGCGCAGCATCTCGCCGATGCGGTTCTCACGGCATTGAGTGTACCGCATCAGGCGATTGCCA
TCACCAGCGCGGAGGCCGTCCGCGTCCTCGGCTCGCTCGGGCCTGCGCTTGAGCCACATTTCGGCACGCCGCTCTTCTCG
GTCGGAGGCGCGACCGCGCGCGCGGCGGGTGGCCTCGGATTTACCGATATCCGCACGGGGCCGGGAACCGGAGAGGGGCT
CGCCGAGACGGTGGCTGCCCACCTCCCCGCTGGCGGAGCCCTGGTCTATCTCGCCGGCTCGCCGCGGACCGGGGGCTTCG
AACGGTCCTTGCACGAAAGGCGGGTCGATTACAGGACCGCCGAATGCTATCGAATGGCGCCGGTCCACTATTCTGCGGAC
ACGCTGCCTGAACTCGTCCGCGCTGGTCCTTTTGATGCGGTGCTGCTCTACTCCCGCGAGACCGCGCGGCGCTTGATCGC
AACATTGCGGGAGAGCCGCCTTCAGCCCGCGGAACTGGCTTCGCGTTGCCTCTGCCTGAGCTGGCCGATCAGAGAGATCC
TGCCGGCCGGCTTTGTCAGCGAGGTTGCAGCGGCGCCCGACGAAGAAAATCTGTTCAGGCTCCTCGAAGCCGAATAG

Upstream 100 bases:

>100_bases
AACATGCGCGATTTACCCCCCGCGTTCCGCTTTGATTTTGCCGGAGGCGCGTGCGGAGATTTCAATCCGATCCTCCCTGA
AATCATAGTGATCTGAGCCG

Downstream 100 bases:

>100_bases
GCGAAGAACCCGGCGGTTCGCCGGCTGGACGGACGTAACTTCAGCGTGTTTGCCCGGCTCATCTGAGGCATTTCCGTCAA
AAAGCACGGGCAGGGGCTTT

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase Protein; Uroporphyrinogen III Synthase

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRVLVTRPRPSAESTAAKLGAMGHETAILPMLQAQHLADAVLTALSVPHQAIAITSAEAVRVLGSLGPALEPHFGTPLFS
VGGATARAAGGLGFTDIRTGPGTGEGLAETVAAHLPAGGALVYLAGSPRTGGFERSLHERRVDYRTAECYRMAPVHYSAD
TLPELVRAGPFDAVLLYSRETARRLIATLRESRLQPAELASRCLCLSWPIREILPAGFVSEVAAAPDEENLFRLLEAE

Sequences:

>Translated_238_residues
MRVLVTRPRPSAESTAAKLGAMGHETAILPMLQAQHLADAVLTALSVPHQAIAITSAEAVRVLGSLGPALEPHFGTPLFS
VGGATARAAGGLGFTDIRTGPGTGEGLAETVAAHLPAGGALVYLAGSPRTGGFERSLHERRVDYRTAECYRMAPVHYSAD
TLPELVRAGPFDAVLLYSRETARRLIATLRESRLQPAELASRCLCLSWPIREILPAGFVSEVAAAPDEENLFRLLEAE
>Mature_238_residues
MRVLVTRPRPSAESTAAKLGAMGHETAILPMLQAQHLADAVLTALSVPHQAIAITSAEAVRVLGSLGPALEPHFGTPLFS
VGGATARAAGGLGFTDIRTGPGTGEGLAETVAAHLPAGGALVYLAGSPRTGGFERSLHERRVDYRTAECYRMAPVHYSAD
TLPELVRAGPFDAVLLYSRETARRLIATLRESRLQPAELASRCLCLSWPIREILPAGFVSEVAAAPDEENLFRLLEAE

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 25197; Mature: 25197

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTRPRPSAESTAAKLGAMGHETAILPMLQAQHLADAVLTALSVPHQAIAITSAEAV
CEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHH
RVLGSLGPALEPHFGTPLFSVGGATARAAGGLGFTDIRTGPGTGEGLAETVAAHLPAGGA
HHHHHCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
LVYLAGSPRTGGFERSLHERRVDYRTAECYRMAPVHYSADTLPELVRAGPFDAVLLYSRE
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCEEEEECHH
TARRLIATLRESRLQPAELASRCLCLSWPIREILPAGFVSEVAAAPDEENLFRLLEAE
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MRVLVTRPRPSAESTAAKLGAMGHETAILPMLQAQHLADAVLTALSVPHQAIAITSAEAV
CEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEECHHHHH
RVLGSLGPALEPHFGTPLFSVGGATARAAGGLGFTDIRTGPGTGEGLAETVAAHLPAGGA
HHHHHCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
LVYLAGSPRTGGFERSLHERRVDYRTAECYRMAPVHYSADTLPELVRAGPFDAVLLYSRE
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCEEEEECHH
TARRLIATLRESRLQPAELASRCLCLSWPIREILPAGFVSEVAAAPDEENLFRLLEAE
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA