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The map label for this gene is rhtC [H]

Identifier: 150398136

GI number: 150398136

Start: 3084991

End: 3085635

Strand: Reverse

Name: rhtC [H]

Synonym: Smed_2939

Alternate gene names: 150398136

Gene position: 3085635-3084991 (Counterclockwise)

Preceding gene: 150398137

Following gene: 150398135

Centisome position: 81.59

GC content: 59.53

Gene sequence:

>645_bases
ATGATGAGCTATCTGATCGAACTCGCTTCACTAATGGCGATCTTCTCTTTCGCCATCGTTTCGCCCGGCGCCGACCTCGC
AATGGTGCTGCGTCAGTCGTTGGTGCACGGCCGCCGATCGGCGATCATAACGTCCTTCGGCATCGGCGCGTCGCTGATGT
TCCACGTGAGCTATACCATTCTCGGCCTCGGGCTGATCATTTCGCAGTCGATCTATCTCTTCAACATCGTGAAATGGTGC
GGCGTAGCCTACCTGATCTATATCGGCATCAAGGCGCTCCGTGCCGGCCAGACGGAAATCGCAGTCGAGGAAACGATGGA
ATCCGGTGAAGCCCCCACGCAGCAGCCGGCGCTGAAGGCCTTCGGCCTCGGCTTTGCCGCCAATGCGCTCAACCCCAAAG
CGGTCTTCTTCTTCCTCTCGATTTTCTCGACGGTCGTCAGCGCCCATACGCCGATAACCGTCAAATTCGGCTATGGACTT
GTCATGGCGAGCGCGTTGATCCTCTGGTTCGTCGGCGTCAGCCTGTTCATGACGACGCCCCGCATGCGGGCGGCCTTCAC
CCGGGCAAGCAAATGGATCGACCGGGCGAGCGGCTTGGTCTTCATCGCCCTCGGACTGAAGCTGGCGACGGAAAAGGCTG
CGTGA

Upstream 100 bases:

>100_bases
CCTACGGGCATCGACAGCCACGGAGTCAGAGGTTAGGTTTTCCGGGGCACGCTATGCGCGCATCCCGCACAGTTGGCATT
GTAAGCACCGGTCGCAAACC

Downstream 100 bases:

>100_bases
TGATCCTCGGCCGCAACGTTCTCTTTGCTTCGATTGTGTTCTCGGCAGCACCGGCTGTTGCGGACGAGTGCATCCAGGCG
CAGGCGGTCTACGCCGATCC

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MMSYLIELASLMAIFSFAIVSPGADLAMVLRQSLVHGRRSAIITSFGIGASLMFHVSYTILGLGLIISQSIYLFNIVKWC
GVAYLIYIGIKALRAGQTEIAVEETMESGEAPTQQPALKAFGLGFAANALNPKAVFFFLSIFSTVVSAHTPITVKFGYGL
VMASALILWFVGVSLFMTTPRMRAAFTRASKWIDRASGLVFIALGLKLATEKAA

Sequences:

>Translated_214_residues
MMSYLIELASLMAIFSFAIVSPGADLAMVLRQSLVHGRRSAIITSFGIGASLMFHVSYTILGLGLIISQSIYLFNIVKWC
GVAYLIYIGIKALRAGQTEIAVEETMESGEAPTQQPALKAFGLGFAANALNPKAVFFFLSIFSTVVSAHTPITVKFGYGL
VMASALILWFVGVSLFMTTPRMRAAFTRASKWIDRASGLVFIALGLKLATEKAA
>Mature_214_residues
MMSYLIELASLMAIFSFAIVSPGADLAMVLRQSLVHGRRSAIITSFGIGASLMFHVSYTILGLGLIISQSIYLFNIVKWC
GVAYLIYIGIKALRAGQTEIAVEETMESGEAPTQQPALKAFGLGFAANALNPKAVFFFLSIFSTVVSAHTPITVKFGYGL
VMASALILWFVGVSLFMTTPRMRAAFTRASKWIDRASGLVFIALGLKLATEKAA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=30.5, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786522, Length=202, Percent_Identity=29.2079207920792, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994979, Length=138, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23059; Mature: 23059

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSYLIELASLMAIFSFAIVSPGADLAMVLRQSLVHGRRSAIITSFGIGASLMFHVSYTI
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHH
LGLGLIISQSIYLFNIVKWCGVAYLIYIGIKALRAGQTEIAVEETMESGEAPTQQPALKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHH
FGLGFAANALNPKAVFFFLSIFSTVVSAHTPITVKFGYGLVMASALILWFVGVSLFMTTP
HCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC
RMRAAFTRASKWIDRASGLVFIALGLKLATEKAA
HHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCC
>Mature Secondary Structure
MMSYLIELASLMAIFSFAIVSPGADLAMVLRQSLVHGRRSAIITSFGIGASLMFHVSYTI
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHH
LGLGLIISQSIYLFNIVKWCGVAYLIYIGIKALRAGQTEIAVEETMESGEAPTQQPALKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHH
FGLGFAANALNPKAVFFFLSIFSTVVSAHTPITVKFGYGLVMASALILWFVGVSLFMTTP
HCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC
RMRAAFTRASKWIDRASGLVFIALGLKLATEKAA
HHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]