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The map label for this gene is atpH [H]

Identifier: 150398122

GI number: 150398122

Start: 3070019

End: 3070585

Strand: Reverse

Name: atpH [H]

Synonym: Smed_2925

Alternate gene names: 150398122

Gene position: 3070585-3070019 (Counterclockwise)

Preceding gene: 150398123

Following gene: 150398121

Centisome position: 81.19

GC content: 60.14

Gene sequence:

>567_bases
GTGCCCGTGGCAGACACATCCCAGCTCATTTCCGGTGTTGCAGAAAGATATGCCTCCTCGCTTTTCGAGCTTGCTCTGGA
AGCCGGATCGATCGAAGCGGTCGGTGCCGACCTGACGCGCATCCAGGCTCTGATCGACGGCAGCGCGGATCTGAAGCGAC
TGATCGTAAGCCCGGTCTTTTCTGCCGACGACCAGTACAAGGCAATTTCGGCCCTCGTCGAGAAGTTCGGCGTCTCCGGG
CTGGTGGGCAACTTCCTCAAAGTCGTCGCGCGCAACCGCCGTCTCTTCGTGCTGCCGGGCATCATCAGGGCATTTCGTCT
GCTCGCTGCCCGCCACAAGGGCGAAATCACTGCCGACGTGACGTCGGCGCATGCGCTGACCCCGGCGCAGGAAACCGAAT
TGAAGGCGGCGCTGAAAGGCGTCACCGGCAAAGACGTGGCGGTAAACGTCACTGTCGACCCGTCTATTCTTGGAGGTCTG
ATCGTCAAGGTCGGTTCCCGCCAGATTGACACCTCCCTTCGCACCAAACTCTCTACCCTTAAGCTTGCACTGAAAGAGGT
CGGCTGA

Upstream 100 bases:

>100_bases
CGCTAGGCCTCGATATCCTGCGAGTTGTTGCAGCAAATTCAAGAGGTTAGGTCTTAGGTTCGCCGGGTCTGACATTCCTG
GATGATTTTGAGAGAAGCTT

Downstream 100 bases:

>100_bases
TGGATATCCGCGCCGCGGAAATTTCCGCTATTCTTAAAGATCAGATCAAAAATTTCGGCCAGGAAGCGGAAGTTTCCGAA
GTGGGTCAGGTGCTTTCCGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MPVADTSQLISGVAERYASSLFELALEAGSIEAVGADLTRIQALIDGSADLKRLIVSPVFSADDQYKAISALVEKFGVSG
LVGNFLKVVARNRRLFVLPGIIRAFRLLAARHKGEITADVTSAHALTPAQETELKAALKGVTGKDVAVNVTVDPSILGGL
IVKVGSRQIDTSLRTKLSTLKLALKEVG

Sequences:

>Translated_188_residues
MPVADTSQLISGVAERYASSLFELALEAGSIEAVGADLTRIQALIDGSADLKRLIVSPVFSADDQYKAISALVEKFGVSG
LVGNFLKVVARNRRLFVLPGIIRAFRLLAARHKGEITADVTSAHALTPAQETELKAALKGVTGKDVAVNVTVDPSILGGL
IVKVGSRQIDTSLRTKLSTLKLALKEVG
>Mature_187_residues
PVADTSQLISGVAERYASSLFELALEAGSIEAVGADLTRIQALIDGSADLKRLIVSPVFSADDQYKAISALVEKFGVSGL
VGNFLKVVARNRRLFVLPGIIRAFRLLAARHKGEITADVTSAHALTPAQETELKAALKGVTGKDVAVNVTVDPSILGGLI
VKVGSRQIDTSLRTKLSTLKLALKEVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=180, Percent_Identity=31.6666666666667, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790173, Length=180, Percent_Identity=30, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984710, Length=177, Percent_Identity=30.5084745762712, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71984717, Length=177, Percent_Identity=30.5084745762712, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320504, Length=180, Percent_Identity=32.2222222222222, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647054, Length=168, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24647056, Length=106, Percent_Identity=36.7924528301887, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 19820; Mature: 19689

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVADTSQLISGVAERYASSLFELALEAGSIEAVGADLTRIQALIDGSADLKRLIVSPVF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SADDQYKAISALVEKFGVSGLVGNFLKVVARNRRLFVLPGIIRAFRLLAARHKGEITADV
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEH
TSAHALTPAQETELKAALKGVTGKDVAVNVTVDPSILGGLIVKVGSRQIDTSLRTKLSTL
HHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHH
KLALKEVG
HHHHHHCC
>Mature Secondary Structure 
PVADTSQLISGVAERYASSLFELALEAGSIEAVGADLTRIQALIDGSADLKRLIVSPVF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SADDQYKAISALVEKFGVSGLVGNFLKVVARNRRLFVLPGIIRAFRLLAARHKGEITADV
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEH
TSAHALTPAQETELKAALKGVTGKDVAVNVTVDPSILGGLIVKVGSRQIDTSLRTKLSTL
HHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHH
KLALKEVG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]