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The map label for this gene is coxS [H]

Identifier: 150398081

GI number: 150398081

Start: 3018936

End: 3019424

Strand: Reverse

Name: coxS [H]

Synonym: Smed_2883

Alternate gene names: 150398081

Gene position: 3019424-3018936 (Counterclockwise)

Preceding gene: 150398083

Following gene: 150398080

Centisome position: 79.84

GC content: 63.19

Gene sequence:

>489_bases
ATGGCGAAAATAACAATGACGGTCAACGGCCGTCAGGTAAGCGGGACTTGCGACGACCGAACGCTGCTGGTGCACTTTAT
CCGCGAAAATCTCGGCCTGACCGGCACCCATGTCGGCTGCGACACGACCCAGTGCGGTGCCTGCGTCGTCCACATCGACG
GGCAATCGGTGAAAAGCTGTTCCATCCTTGCCGCCCAGGCGGCCGGTTCGTCTGTGACGACGATCGAGGGGCTGGCGTCC
AACGGCGAGCTTCATCCGGTGCAGGCGGCCTTCAAGACACATCACGGACTGCAATGCGGCTTCTGCACGCCGGGAATGGT
CATGGCGGCCGTCGATATGATCCGTCGCCACGGCAGCAGTCTTGACGAGGCGACCGTGCGCACCGAGCTCGAAGGCAATA
TCTGTCGTTGCACCGGCTATCACAACATCGTCCAGGCGATCCTGGCCGCCGCGGCCGAGACGGGCGGCGTTCGGCAGGCT
GCCGAATGA

Upstream 100 bases:

>100_bases
AAGGGCATTTGATATCGGTCGGCGCGTGCTTCCTGTCGCGTGAACGCATCTCACCCGATTTGAAACCGTGCTCGACTCTG
GACCGACCCGGAGGAGCGAA

Downstream 100 bases:

>100_bases
AGAAATCCCTGAGGGAGCGCGATGCGGGGGGAGCGCCGCCGCATTTTTCGTCATTCCGCAAACGGAAATTCGTTACTGGA
TTTCGGGAGGAGACAGGCAA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAKITMTVNGRQVSGTCDDRTLLVHFIRENLGLTGTHVGCDTTQCGACVVHIDGQSVKSCSILAAQAAGSSVTTIEGLAS
NGELHPVQAAFKTHHGLQCGFCTPGMVMAAVDMIRRHGSSLDEATVRTELEGNICRCTGYHNIVQAILAAAAETGGVRQA
AE

Sequences:

>Translated_162_residues
MAKITMTVNGRQVSGTCDDRTLLVHFIRENLGLTGTHVGCDTTQCGACVVHIDGQSVKSCSILAAQAAGSSVTTIEGLAS
NGELHPVQAAFKTHHGLQCGFCTPGMVMAAVDMIRRHGSSLDEATVRTELEGNICRCTGYHNIVQAILAAAAETGGVRQA
AE
>Mature_161_residues
AKITMTVNGRQVSGTCDDRTLLVHFIRENLGLTGTHVGCDTTQCGACVVHIDGQSVKSCSILAAQAAGSSVTTIEGLASN
GELHPVQAAFKTHHGLQCGFCTPGMVMAAVDMIRRHGSSLDEATVRTELEGNICRCTGYHNIVQAILAAAAETGGVRQAA
E

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=174, Percent_Identity=39.0804597701149, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=37.8205128205128, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=41.4201183431953, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=41.0958904109589, Blast_Score=108, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=166, Percent_Identity=37.9518072289157, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=167, Percent_Identity=32.9341317365269, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=32.484076433121, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=37.3417721518987, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=37.012987012987, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647193, Length=140, Percent_Identity=36.4285714285714, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647199, Length=134, Percent_Identity=36.5671641791045, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647197, Length=145, Percent_Identity=31.7241379310345, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647195, Length=166, Percent_Identity=30.7228915662651, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16881; Mature: 16750

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKITMTVNGRQVSGTCDDRTLLVHFIRENLGLTGTHVGCDTTQCGACVVHIDGQSVKSC
CEEEEEEECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHH
SILAAQAAGSSVTTIEGLASNGELHPVQAAFKTHHGLQCGFCTPGMVMAAVDMIRRHGSS
HEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCC
LDEATVRTELEGNICRCTGYHNIVQAILAAAAETGGVRQAAE
CCHHHEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AKITMTVNGRQVSGTCDDRTLLVHFIRENLGLTGTHVGCDTTQCGACVVHIDGQSVKSC
EEEEEEECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHH
SILAAQAAGSSVTTIEGLASNGELHPVQAAFKTHHGLQCGFCTPGMVMAAVDMIRRHGSS
HEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCC
LDEATVRTELEGNICRCTGYHNIVQAILAAAAETGGVRQAAE
CCHHHEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]