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The map label for this gene is dppA [H]

Identifier: 150398055

GI number: 150398055

Start: 2983926

End: 2985554

Strand: Reverse

Name: dppA [H]

Synonym: Smed_2857

Alternate gene names: 150398055

Gene position: 2985554-2983926 (Counterclockwise)

Preceding gene: 150398057

Following gene: 150398054

Centisome position: 78.94

GC content: 62.12

Gene sequence:

>1629_bases
ATGCTTCTCATCAACAGGCGCGGCGCGCTGGGGCTCATCGGCGCAACTGCGGGCAGCATGATCCTGCCGCGCTTCGCCGT
GGGTCAGGGCACGCGCCCATCCGTCACCATCGCCGTGCAGAAGATCACCATCAACAACACGCTCGACGTCTGGAACGAGC
AGTCGAATGTCGGCGAGCGTGTGTTCTTCCCCAACCTCTGGGAAGGCCTGATCCTGCGCAACTGGATGGGCGATCAGGGT
CCGGTTCCCGGCCTTGCGACGGAATGGAAGCGCATTGACGACAAAACGCTCGAGCTGAAGCTGCGCCAGGGCGTAAAGTT
CCATAATGGCGACGAACTCACGGCCGACGACGTCGTCTTCAGCTTCTCGGCGCAGCGCGTGTTCGGGGACACCCAGCCTG
CCGGCGGCAAGACGGTCTTCGAGGATGAGCACAAGCCGGCGACTGCGAAGGAACTGCCTGCGGTCGTGCCGGGTACCGGT
CGCCGCCTGTGGCCGGCGCTGGCCGGTGTCGAGGCAGTCGACAAGTATACCGTGCGTTTCCACAACGCGACGCCCGACGT
CACCATCGAGGGCCGCCTTTATGCATTCGGCAGCCAGATCGCAAATCGTCGCGCCTGGGATGAGGCGCCGACCTACATGG
ATTGGGCACGCAAGCCGATCACCACCGGGCCCTACAGGGTCGGCGAACATAAGCCGGACGTGTCCCTGACGCTGGTTGCC
TTCGACGACTATTGGGGAGGCCGCCCGCCACTCGAGCAAATCCGTTTCGTTGAGGTTCCGGAGGTCTCGTCTCGCGTGAA
CGGGCTCCTCTCCGGCGAATATGATTTCGCCTGCGACCTGCCGCCGGACCAGATCGCTGCCGTTCAGGCCGCACCGGGCT
ACGAGGTTCAGGGCTCGACGATCCACAACCACCGCATCTCGGTCTTCAATGTCCAGAACCCGACCCTTCAGGATCCGCTC
GTCCGCCGCGCCATGACCCATTCGGTCGATCGCCAGGCGATCGTCGATGCGCTCTGGGCCGGACAGACGACCGTCCCCGC
TGGCCTGCAATTTCCGTTCTACGGGGATATGTTCGTCGAAGGCTGGGCGGTCCCTGAATACGATCCGCAACTGGCCAAGG
ACCTCTTGAAGCAGGCCAATTACAAAGGGGATGCGATCCCGTTCCGCCTTCTCAACAACTACTATACGAACCAGACCGCA
AACGGCCAGATCATGGTCGAGATGTGGAAGCAGGTCGGGCTGAACGTCGAGATTGAAATGAAGGAGAACTGGGGCCAGAT
CCACGACCCGTCGGGCGTCAAGGGCGTGCGCGACTGGTCAGCCGGTGCAGCCTTCAGCGACCCCGTCTCCTCGATCGTTG
CCCAGTTCGGACCCAATGGCGAGGTCCAGCAGAAGAAGGACTGGTCGAACGCCGAGGCCAACCAGATGTCCCAGATCCTC
GAAACGGAAACCGATCAGGCAAAGCGCAAGAAGGCATTTGCCCGCATGCTCGAAATCTGCGAGCGCGAAGACCCGGTCTA
TCAGGTGCTTCATCAGAATGCGGTCTTCACCGGAATGAAATCCTCTTTGAAGTGGAAGGCGGCACCCGCCTTCGCCATGG
ATTTCCGCGCCGCCAACTGGTCCAGCTGA

Upstream 100 bases:

>100_bases
GAAAGTTTCACCCAAACATCAGGAAGACGACGTCTGGCGGAACTAGCAACGATCCGAACAGCGCCCGCACGGGTGCTCGG
AGCATTCAAAGGAGATTCTC

Downstream 100 bases:

>100_bases
GATCGAATAACCCAGTTTCCGGCAGCCGGTGGGCTGCCGGAGTTTTCAGGGCCGGCCGGCAATGCCGCGGCCGAAGCACC
GGGAATGAGCAATGGGCACT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MLLINRRGALGLIGATAGSMILPRFAVGQGTRPSVTIAVQKITINNTLDVWNEQSNVGERVFFPNLWEGLILRNWMGDQG
PVPGLATEWKRIDDKTLELKLRQGVKFHNGDELTADDVVFSFSAQRVFGDTQPAGGKTVFEDEHKPATAKELPAVVPGTG
RRLWPALAGVEAVDKYTVRFHNATPDVTIEGRLYAFGSQIANRRAWDEAPTYMDWARKPITTGPYRVGEHKPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQAAPGYEVQGSTIHNHRISVFNVQNPTLQDPL
VRRAMTHSVDRQAIVDALWAGQTTVPAGLQFPFYGDMFVEGWAVPEYDPQLAKDLLKQANYKGDAIPFRLLNNYYTNQTA
NGQIMVEMWKQVGLNVEIEMKENWGQIHDPSGVKGVRDWSAGAAFSDPVSSIVAQFGPNGEVQQKKDWSNAEANQMSQIL
ETETDQAKRKKAFARMLEICEREDPVYQVLHQNAVFTGMKSSLKWKAAPAFAMDFRAANWSS

Sequences:

>Translated_542_residues
MLLINRRGALGLIGATAGSMILPRFAVGQGTRPSVTIAVQKITINNTLDVWNEQSNVGERVFFPNLWEGLILRNWMGDQG
PVPGLATEWKRIDDKTLELKLRQGVKFHNGDELTADDVVFSFSAQRVFGDTQPAGGKTVFEDEHKPATAKELPAVVPGTG
RRLWPALAGVEAVDKYTVRFHNATPDVTIEGRLYAFGSQIANRRAWDEAPTYMDWARKPITTGPYRVGEHKPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQAAPGYEVQGSTIHNHRISVFNVQNPTLQDPL
VRRAMTHSVDRQAIVDALWAGQTTVPAGLQFPFYGDMFVEGWAVPEYDPQLAKDLLKQANYKGDAIPFRLLNNYYTNQTA
NGQIMVEMWKQVGLNVEIEMKENWGQIHDPSGVKGVRDWSAGAAFSDPVSSIVAQFGPNGEVQQKKDWSNAEANQMSQIL
ETETDQAKRKKAFARMLEICEREDPVYQVLHQNAVFTGMKSSLKWKAAPAFAMDFRAANWSS
>Mature_542_residues
MLLINRRGALGLIGATAGSMILPRFAVGQGTRPSVTIAVQKITINNTLDVWNEQSNVGERVFFPNLWEGLILRNWMGDQG
PVPGLATEWKRIDDKTLELKLRQGVKFHNGDELTADDVVFSFSAQRVFGDTQPAGGKTVFEDEHKPATAKELPAVVPGTG
RRLWPALAGVEAVDKYTVRFHNATPDVTIEGRLYAFGSQIANRRAWDEAPTYMDWARKPITTGPYRVGEHKPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQAAPGYEVQGSTIHNHRISVFNVQNPTLQDPL
VRRAMTHSVDRQAIVDALWAGQTTVPAGLQFPFYGDMFVEGWAVPEYDPQLAKDLLKQANYKGDAIPFRLLNNYYTNQTA
NGQIMVEMWKQVGLNVEIEMKENWGQIHDPSGVKGVRDWSAGAAFSDPVSSIVAQFGPNGEVQQKKDWSNAEANQMSQIL
ETETDQAKRKKAFARMLEICEREDPVYQVLHQNAVFTGMKSSLKWKAAPAFAMDFRAANWSS

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=371, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787551, Length=312, Percent_Identity=25, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789887, Length=326, Percent_Identity=25.4601226993865, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787052, Length=439, Percent_Identity=24.1457858769932, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60337; Mature: 60337

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLINRRGALGLIGATAGSMILPRFAVGQGTRPSVTIAVQKITINNTLDVWNEQSNVGER
CEEEECCCCEEEEECCCCCHHCCHHHCCCCCCCEEEEEEEEEEECCCHHCCCCCCCCCCE
VFFPNLWEGLILRNWMGDQGPVPGLATEWKRIDDKTLELKLRQGVKFHNGDELTADDVVF
EECCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHEEEHHHCCCCCCCCCCCCHHHEEE
SFSAQRVFGDTQPAGGKTVFEDEHKPATAKELPAVVPGTGRRLWPALAGVEAVDKYTVRF
EEEHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCEEEEEE
HNATPDVTIEGRLYAFGSQIANRRAWDEAPTYMDWARKPITTGPYRVGEHKPDVSLTLVA
ECCCCCEEECCEEEEEHHHHHHCCCCCCCCCHHHHHCCCCCCCCEECCCCCCCCEEEEEE
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQAAPGYEVQGST
EECCCCCCCCHHHCEEEECCCHHHHHCCEECCCCCEEECCCHHHEEEEECCCCCEECCCE
IHNHRISVFNVQNPTLQDPLVRRAMTHSVDRQAIVDALWAGQTTVPAGLQFPFYGDMFVE
EECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GWAVPEYDPQLAKDLLKQANYKGDAIPFRLLNNYYTNQTANGQIMVEMWKQVGLNVEIEM
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEHEEHHHHHCCCEEEEE
KENWGQIHDPSGVKGVRDWSAGAAFSDPVSSIVAQFGPNGEVQQKKDWSNAEANQMSQIL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
ETETDQAKRKKAFARMLEICEREDPVYQVLHQNAVFTGMKSSLKWKAAPAFAMDFRAANW
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHCHHHCCEECCCCCEEEEECCCCC
SS
CC
>Mature Secondary Structure
MLLINRRGALGLIGATAGSMILPRFAVGQGTRPSVTIAVQKITINNTLDVWNEQSNVGER
CEEEECCCCEEEEECCCCCHHCCHHHCCCCCCCEEEEEEEEEEECCCHHCCCCCCCCCCE
VFFPNLWEGLILRNWMGDQGPVPGLATEWKRIDDKTLELKLRQGVKFHNGDELTADDVVF
EECCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHEEEHHHCCCCCCCCCCCCHHHEEE
SFSAQRVFGDTQPAGGKTVFEDEHKPATAKELPAVVPGTGRRLWPALAGVEAVDKYTVRF
EEEHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCEEEEEE
HNATPDVTIEGRLYAFGSQIANRRAWDEAPTYMDWARKPITTGPYRVGEHKPDVSLTLVA
ECCCCCEEECCEEEEEHHHHHHCCCCCCCCCHHHHHCCCCCCCCEECCCCCCCCEEEEEE
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQAAPGYEVQGST
EECCCCCCCCHHHCEEEECCCHHHHHCCEECCCCCEEECCCHHHEEEEECCCCCEECCCE
IHNHRISVFNVQNPTLQDPLVRRAMTHSVDRQAIVDALWAGQTTVPAGLQFPFYGDMFVE
EECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GWAVPEYDPQLAKDLLKQANYKGDAIPFRLLNNYYTNQTANGQIMVEMWKQVGLNVEIEM
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEHEEHHHHHCCCEEEEE
KENWGQIHDPSGVKGVRDWSAGAAFSDPVSSIVAQFGPNGEVQQKKDWSNAEANQMSQIL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
ETETDQAKRKKAFARMLEICEREDPVYQVLHQNAVFTGMKSSLKWKAAPAFAMDFRAANW
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHCHHHCCEECCCCCEEEEECCCCC
SS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]