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The map label for this gene is pntAB [H]

Identifier: 150397956

GI number: 150397956

Start: 2877600

End: 2878010

Strand: Reverse

Name: pntAB [H]

Synonym: Smed_2758

Alternate gene names: 150397956

Gene position: 2878010-2877600 (Counterclockwise)

Preceding gene: 150397957

Following gene: 150397955

Centisome position: 76.1

GC content: 62.53

Gene sequence:

>411_bases
ATGGCGAACGAACTTCTGGACAAGGCGCTCGTCGATCTTGAACGGGCAGTCGAGGCGGTGAGGACCGCCGCCGAATACGT
ACCGGATGCGGCCGGAGCGGTTGCGCATGGCGCGACGGGCGGCGCGATCGACCCCTTCGTCTTTCGGCTCGCGATTTTCG
TGCTGGCGATTTTCGTAGGCTACTACGTCGTGTGGTCGGTGACGCCGGCCCTGCACACGCCCCTGATGGCGGTGACCAAT
GCGATCTCGTCGGTGATCGTCGTCGGCGCCTTGCTCGCGGTCGGCATCTCCGCCTCGGGACTGGCCACCGGCTTCGGCTT
CGTCGCGCTGGTGCTTGCTTCGGTGAACATATTCGGTGGCTTCCTGGTCACTCAGCGCATGCTTGCCATGTACAAGAAAA
AAGAAAAGTGA

Upstream 100 bases:

>100_bases
GTTGAACATGGAGGATGAGCTCGTAAAGGCTACGGCACTGACTCACGGCGGGTCCGTCGTGCATCCGGCCTTCGGCGGTG
CCATGAAGGGGGAGAAGTAA

Downstream 100 bases:

>100_bases
GGCGGGCCGATGAACGCTAATTTTGCTGCCTTCCTCTATCTCGTCTCGGGCGTGCTCTTCATCATGGCGCTGCGCGGGCT
CTCGCATCCGACCACCAGCC

Product: putative NAD(P) transhydrogenase subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MANELLDKALVDLERAVEAVRTAAEYVPDAAGAVAHGATGGAIDPFVFRLAIFVLAIFVGYYVVWSVTPALHTPLMAVTN
AISSVIVVGALLAVGISASGLATGFGFVALVLASVNIFGGFLVTQRMLAMYKKKEK

Sequences:

>Translated_136_residues
MANELLDKALVDLERAVEAVRTAAEYVPDAAGAVAHGATGGAIDPFVFRLAIFVLAIFVGYYVVWSVTPALHTPLMAVTN
AISSVIVVGALLAVGISASGLATGFGFVALVLASVNIFGGFLVTQRMLAMYKKKEK
>Mature_135_residues
ANELLDKALVDLERAVEAVRTAAEYVPDAAGAVAHGATGGAIDPFVFRLAIFVLAIFVGYYVVWSVTPALHTPLMAVTNA
ISSVIVVGALLAVGISASGLATGFGFVALVLASVNIFGGFLVTQRMLAMYKKKEK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=136, Percent_Identity=43.3823529411765, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI122939153, Length=136, Percent_Identity=43.3823529411765, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1787887, Length=89, Percent_Identity=58.4269662921348, Blast_Score=107, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=85, Percent_Identity=52.9411764705882, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 14157; Mature: 14026

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANELLDKALVDLERAVEAVRTAAEYVPDAAGAVAHGATGGAIDPFVFRLAIFVLAIFVG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YYVVWSVTPALHTPLMAVTNAISSVIVVGALLAVGISASGLATGFGFVALVLASVNIFGG
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FLVTQRMLAMYKKKEK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANELLDKALVDLERAVEAVRTAAEYVPDAAGAVAHGATGGAIDPFVFRLAIFVLAIFVG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YYVVWSVTPALHTPLMAVTNAISSVIVVGALLAVGISASGLATGFGFVALVLASVNIFGG
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FLVTQRMLAMYKKKEK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]