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The map label for this gene is 150397935

Identifier: 150397935

GI number: 150397935

Start: 2849558

End: 2850436

Strand: Direct

Name: 150397935

Synonym: Smed_2737

Alternate gene names: NA

Gene position: 2849558-2850436 (Clockwise)

Preceding gene: 150397934

Following gene: 150397936

Centisome position: 75.35

GC content: 63.37

Gene sequence:

>879_bases
ATGCTCTATGACATCAGCCTGAAGATCACCTACGGTTACGAGGCTCCGGTAAGCGGCGGCAGGCATCTCGTGCGCGTACT
GCCTGTCTCCATTCCCGAGCGCCAGCGTCTCGTTGCGGGATCGGTGACTTGCCAGCCGGCGCCAGACGAGCGGCTGGAAG
GCAGGGACTTCTTTGCCAATCATACGACGTCCATCCTGTTCCGATCCGCGCACGATCATCTCGTCATCCTCATGAAAGCG
CGCATTCAGGCGGAGACGCCTGCGATCACGGCCGATCTGTCACCTCCGCTCGGCGCCCTTCCCGCCGAGCTTGCCGGCTT
GTGGTCCGTCGATTCGGAATCTCCCCATCATTTCATCGGTCCAAGTCCGCTCCTGCCGGCCGTGCCGGAGATCGCCGCCT
ATGCCCGCGCCATCGCCGGCGAAAACATGACGATCGAGCAGATCGGGGCCAGCATCTGTAATCGCATCCATCGAGACTTC
GTCTACGACGCCGAGGCAACGACCGTGAACACCACGGCCGCGCAAACCTTCGAGCTGAAGCGCGGCGTCTGCCAGGACTT
CGCCCATGTGATGATCGTGGCGCTGCGCAGTCTCGGTATCCCGGCCGGCTATGTCAGCGGGTTCCTAAGAACCCTGCCGC
CGCCGGGCCAGGAGCGGCTCGAAGGCGCCGATGCCATGCATGCATGGGTCCGTTTCTGGTGCGGCACCAACTGCGGCTGG
CTCGAACTCGATCCGACCAATAATATTCGCGCCGGCACCGACCACATCGTGGTCGGCCATGGCCGCGATTACGGCGACGT
GGCACCGGTGATCGGGGTGCTGAAAGGCTACGGCAGTCACACGACGGAACAGGCCGTCGACGTCGTTCCAGTCGGATGA

Upstream 100 bases:

>100_bases
AGGCGATGGACATGGCCGTCTACAGCCGGCTCGAGCAGGATCTCCAGGGGCTCTCGGACCTGCTTGCGCAGACCTATCTC
GGCTGATGGAGGCGGGTTCC

Downstream 100 bases:

>100_bases
CCCGGAACGGGACAGGCGTCCCGTTCCCGCACAAGCGGCCATTCAAGGAACCCCAGAATAAGCAGAGGTTTTTTCGGCAG
TTGGATAAAATTGCACCGAC

Product: transglutaminase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLYDISLKITYGYEAPVSGGRHLVRVLPVSIPERQRLVAGSVTCQPAPDERLEGRDFFANHTTSILFRSAHDHLVILMKA
RIQAETPAITADLSPPLGALPAELAGLWSVDSESPHHFIGPSPLLPAVPEIAAYARAIAGENMTIEQIGASICNRIHRDF
VYDAEATTVNTTAAQTFELKRGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADAMHAWVRFWCGTNCGW
LELDPTNNIRAGTDHIVVGHGRDYGDVAPVIGVLKGYGSHTTEQAVDVVPVG

Sequences:

>Translated_292_residues
MLYDISLKITYGYEAPVSGGRHLVRVLPVSIPERQRLVAGSVTCQPAPDERLEGRDFFANHTTSILFRSAHDHLVILMKA
RIQAETPAITADLSPPLGALPAELAGLWSVDSESPHHFIGPSPLLPAVPEIAAYARAIAGENMTIEQIGASICNRIHRDF
VYDAEATTVNTTAAQTFELKRGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADAMHAWVRFWCGTNCGW
LELDPTNNIRAGTDHIVVGHGRDYGDVAPVIGVLKGYGSHTTEQAVDVVPVG
>Mature_292_residues
MLYDISLKITYGYEAPVSGGRHLVRVLPVSIPERQRLVAGSVTCQPAPDERLEGRDFFANHTTSILFRSAHDHLVILMKA
RIQAETPAITADLSPPLGALPAELAGLWSVDSESPHHFIGPSPLLPAVPEIAAYARAIAGENMTIEQIGASICNRIHRDF
VYDAEATTVNTTAAQTFELKRGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADAMHAWVRFWCGTNCGW
LELDPTNNIRAGTDHIVVGHGRDYGDVAPVIGVLKGYGSHTTEQAVDVVPVG

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 31531; Mature: 31531

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDISLKITYGYEAPVSGGRHLVRVLPVSIPERQRLVAGSVTCQPAPDERLEGRDFFAN
CEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHEEECCEECCCCCCCCCCCCHHHHC
HTTSILFRSAHDHLVILMKARIQAETPAITADLSPPLGALPAELAGLWSVDSESPHHFIG
CHHEEEEECCCCCEEEEEEEHHCCCCCEEEEECCCCCCCCHHHHHHEECCCCCCCCCCCC
PSPLLPAVPEIAAYARAIAGENMTIEQIGASICNRIHRDFVYDAEATTVNTTAAQTFELK
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEECHHHHHHHHH
RGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADAMHAWVRFWCGTNCGW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCE
LELDPTNNIRAGTDHIVVGHGRDYGDVAPVIGVLKGYGSHTTEQAVDVVPVG
EEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHCEEEEECC
>Mature Secondary Structure
MLYDISLKITYGYEAPVSGGRHLVRVLPVSIPERQRLVAGSVTCQPAPDERLEGRDFFAN
CEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHEEECCEECCCCCCCCCCCCHHHHC
HTTSILFRSAHDHLVILMKARIQAETPAITADLSPPLGALPAELAGLWSVDSESPHHFIG
CHHEEEEECCCCCEEEEEEEHHCCCCCEEEEECCCCCCCCHHHHHHEECCCCCCCCCCCC
PSPLLPAVPEIAAYARAIAGENMTIEQIGASICNRIHRDFVYDAEATTVNTTAAQTFELK
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEECHHHHHHHHH
RGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADAMHAWVRFWCGTNCGW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCE
LELDPTNNIRAGTDHIVVGHGRDYGDVAPVIGVLKGYGSHTTEQAVDVVPVG
EEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]