Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 150397901

GI number: 150397901

Start: 2810824

End: 2812389

Strand: Direct

Name: xylB [H]

Synonym: Smed_2703

Alternate gene names: 150397901

Gene position: 2810824-2812389 (Clockwise)

Preceding gene: 150397900

Following gene: 150397902

Centisome position: 74.32

GC content: 65.39

Gene sequence:

>1566_bases
ATGCGCTGCGGTCTGAGGAGGACGGAAGGACCGCGTGGTCTTGCGTCGCGGAGGAGGTACGCAATGCAGCCGGACGAACG
CTATGTCATCGGCCTGGATTCATCGACTCAATCCGTCAAGGCAGTCGCCTGGACGGCCGATGGCACACCGCGGGCCGAAG
GCCGTGCACCGCACCGCATTTCGACGCCGCATCCACTAAAGGCGGAGCAGAACGCCGAGGACTGGTGGTCGGCCGCCTGC
GACGCCCTGTCCTCGCTCCTGCGCCAGATCGATTCTCACCGCGTCGACGGTGTCGCAATATCCAACCAGCGCGAAACAAT
GGTTCTTCTCGGCGTGGACCGGAAGCCGCTCAGCCCGGCAACCCTCTGGCTCGACCGCCGGGCGCAGGACATCGTGCAGC
CGTTCGCCGATGAATTCGGCAGCGAGCGCCTGCATGCGATCTCGGGCAAGCCGATCGACGTCATTCCGTGCGTATATCGC
CTTCGTTACTATCGCCAGCATGAGCCGGAATTGCTCGACCGCGCGGCGCAGATCCTGAGTGTACACGATTTCCTGACACA
GAAGCTGACGGGTGAAGCCGCTGCAAGCTGGACGAGCGCCGACCCTTTCGGCATCCTCGACATCGAGGCGAAGCAATGGT
CCCGCGAAATTCTCGATCATCTCGATATTCCTCTCAGCAAGCTGCCGCCGCTTCACCGGCCCGGCACGCTGATCGGCCGC
GTGACTGCGGACGCCGCGGCCGCGACGGGGCTTGCCGCGGGCGTGCCGGTCTATGCCGGCGGCGGTGATGGACATTGTGC
GGGGCTCGGCGTCAATGTGATCGAGCCGGGGGTCGTCTATCTTAATCTCGGCACGGCAGTGGTCGGCGGCTGCTGGACGC
CGACGCGCAAGCTCAGCCGCTACTGGCGCACGCTGGTCTCGCCAAGCGGCGAAGGCTACCTGCTCGAAAGCTGCCAGCGC
GGCGGCGCTTATTTCGTCAACTGGCTGCTGGACACCTTTGCCGGCGGCCGGTCCGATCCGGCTATTTTCGAACGGCTCGA
AGCGGAGGCCGCCAGCCTGGATGTCGGCTCCGGCGGAGTCACCGTTTGCTCCTATCTCATGGGCTGCATGGATCCGCACT
GGGACGCGGATGCCCGAGCTACCTTCAGCGGCATGGGTCCGGAGACAGGCATGGGCCATCTCTACCGTGCCTCCATGGAG
GCCATCACGCTTGAATTCGTCCGGTCTCTTTCCGAGATGAAATCGATGGGCGTGGCGGCCGACCGGATCTTCGTCATCGG
CGGTGGCGCCGGTAGCGCCCTCTGGCGGCAGATGATCGCCGACGCAAGCGGACTCCCCGTCATACGCAGCCTTTCCAACG
AGGCTTCCGCACTCGGCGCCGGCATGTCTGCTGCGATAGGTGCCGGCTGGTACGGGCATTTCGGCGAGGCCGCCGGCGCC
ATGTCACGGCTTGCCGAACAGATCGACCCGCGGCCTGCCGCTGCACAGGCATGGGCCGCACTATCCCGCAGGCAGGCGAA
CCTCTATCAGGCAACCCGCCGCCTGGATGCCTATGATGGCCCCTGA

Upstream 100 bases:

>100_bases
TTTCGTGACAGACATCGCTACGGGAGAGGCGTTGCTGGCGGAGTGATGGGCTGCCGGCAGGCGAGACCGGCGCCCGACGG
AAAGGGAGGAAGGCCGCCGC

Downstream 100 bases:

>100_bases
CGCATTCGTGCCGGACAGTCGCACGCCTGCTTGAATTGTCGTCGCGAATCGCCACCTGATGTTTCGGGCGCGACTCCGAA
CGTTGGAGTTGCAAAAGGGA

Product: carbohydrate kinase FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRCGLRRTEGPRGLASRRRYAMQPDERYVIGLDSSTQSVKAVAWTADGTPRAEGRAPHRISTPHPLKAEQNAEDWWSAAC
DALSSLLRQIDSHRVDGVAISNQRETMVLLGVDRKPLSPATLWLDRRAQDIVQPFADEFGSERLHAISGKPIDVIPCVYR
LRYYRQHEPELLDRAAQILSVHDFLTQKLTGEAAASWTSADPFGILDIEAKQWSREILDHLDIPLSKLPPLHRPGTLIGR
VTADAAAATGLAAGVPVYAGGGDGHCAGLGVNVIEPGVVYLNLGTAVVGGCWTPTRKLSRYWRTLVSPSGEGYLLESCQR
GGAYFVNWLLDTFAGGRSDPAIFERLEAEAASLDVGSGGVTVCSYLMGCMDPHWDADARATFSGMGPETGMGHLYRASME
AITLEFVRSLSEMKSMGVAADRIFVIGGGAGSALWRQMIADASGLPVIRSLSNEASALGAGMSAAIGAGWYGHFGEAAGA
MSRLAEQIDPRPAAAQAWAALSRRQANLYQATRRLDAYDGP

Sequences:

>Translated_521_residues
MRCGLRRTEGPRGLASRRRYAMQPDERYVIGLDSSTQSVKAVAWTADGTPRAEGRAPHRISTPHPLKAEQNAEDWWSAAC
DALSSLLRQIDSHRVDGVAISNQRETMVLLGVDRKPLSPATLWLDRRAQDIVQPFADEFGSERLHAISGKPIDVIPCVYR
LRYYRQHEPELLDRAAQILSVHDFLTQKLTGEAAASWTSADPFGILDIEAKQWSREILDHLDIPLSKLPPLHRPGTLIGR
VTADAAAATGLAAGVPVYAGGGDGHCAGLGVNVIEPGVVYLNLGTAVVGGCWTPTRKLSRYWRTLVSPSGEGYLLESCQR
GGAYFVNWLLDTFAGGRSDPAIFERLEAEAASLDVGSGGVTVCSYLMGCMDPHWDADARATFSGMGPETGMGHLYRASME
AITLEFVRSLSEMKSMGVAADRIFVIGGGAGSALWRQMIADASGLPVIRSLSNEASALGAGMSAAIGAGWYGHFGEAAGA
MSRLAEQIDPRPAAAQAWAALSRRQANLYQATRRLDAYDGP
>Mature_521_residues
MRCGLRRTEGPRGLASRRRYAMQPDERYVIGLDSSTQSVKAVAWTADGTPRAEGRAPHRISTPHPLKAEQNAEDWWSAAC
DALSSLLRQIDSHRVDGVAISNQRETMVLLGVDRKPLSPATLWLDRRAQDIVQPFADEFGSERLHAISGKPIDVIPCVYR
LRYYRQHEPELLDRAAQILSVHDFLTQKLTGEAAASWTSADPFGILDIEAKQWSREILDHLDIPLSKLPPLHRPGTLIGR
VTADAAAATGLAAGVPVYAGGGDGHCAGLGVNVIEPGVVYLNLGTAVVGGCWTPTRKLSRYWRTLVSPSGEGYLLESCQR
GGAYFVNWLLDTFAGGRSDPAIFERLEAEAASLDVGSGGVTVCSYLMGCMDPHWDADARATFSGMGPETGMGHLYRASME
AITLEFVRSLSEMKSMGVAADRIFVIGGGAGSALWRQMIADASGLPVIRSLSNEASALGAGMSAAIGAGWYGHFGEAAGA
MSRLAEQIDPRPAAAQAWAALSRRQANLYQATRRLDAYDGP

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=529, Percent_Identity=24.952741020794, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI41393575, Length=415, Percent_Identity=24.578313253012, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI42794763, Length=391, Percent_Identity=22.7621483375959, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4504007, Length=391, Percent_Identity=23.0179028132992, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI189409120, Length=391, Percent_Identity=22.7621483375959, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI164663830, Length=277, Percent_Identity=28.158844765343, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789138, Length=496, Percent_Identity=26.008064516129, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1789987, Length=447, Percent_Identity=28.6353467561521, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790005, Length=503, Percent_Identity=25.4473161033797, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787789, Length=517, Percent_Identity=25.531914893617, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1789168, Length=459, Percent_Identity=26.797385620915, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1790361, Length=472, Percent_Identity=23.728813559322, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=452, Percent_Identity=23.8938053097345, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17864214, Length=430, Percent_Identity=24.6511627906977, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654573, Length=418, Percent_Identity=25.1196172248804, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24657106, Length=518, Percent_Identity=22.972972972973, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24657102, Length=518, Percent_Identity=22.972972972973, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 56086; Mature: 56086

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCGLRRTEGPRGLASRRRYAMQPDERYVIGLDSSTQSVKAVAWTADGTPRAEGRAPHRI
CCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCC
STPHPLKAEQNAEDWWSAACDALSSLLRQIDSHRVDGVAISNQRETMVLLGVDRKPLSPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCHH
TLWLDRRAQDIVQPFADEFGSERLHAISGKPIDVIPCVYRLRYYRQHEPELLDRAAQILS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VHDFLTQKLTGEAAASWTSADPFGILDIEAKQWSREILDHLDIPLSKLPPLHRPGTLIGR
HHHHHHHHHCCHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEE
VTADAAAATGLAAGVPVYAGGGDGHCAGLGVNVIEPGVVYLNLGTAVVGGCWTPTRKLSR
HHHHHHHHHHHHCCCCEEECCCCCCEEECCCEEECCCEEEEEECHHHHCCCCCHHHHHHH
YWRTLVSPSGEGYLLESCQRGGAYFVNWLLDTFAGGRSDPAIFERLEAEAASLDVGSGGV
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
TVCSYLMGCMDPHWDADARATFSGMGPETGMGHLYRASMEAITLEFVRSLSEMKSMGVAA
HHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DRIFVIGGGAGSALWRQMIADASGLPVIRSLSNEASALGAGMSAAIGAGWYGHFGEAAGA
CEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
MSRLAEQIDPRPAAAQAWAALSRRQANLYQATRRLDAYDGP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRCGLRRTEGPRGLASRRRYAMQPDERYVIGLDSSTQSVKAVAWTADGTPRAEGRAPHRI
CCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCC
STPHPLKAEQNAEDWWSAACDALSSLLRQIDSHRVDGVAISNQRETMVLLGVDRKPLSPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCHH
TLWLDRRAQDIVQPFADEFGSERLHAISGKPIDVIPCVYRLRYYRQHEPELLDRAAQILS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VHDFLTQKLTGEAAASWTSADPFGILDIEAKQWSREILDHLDIPLSKLPPLHRPGTLIGR
HHHHHHHHHCCHHHCCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEE
VTADAAAATGLAAGVPVYAGGGDGHCAGLGVNVIEPGVVYLNLGTAVVGGCWTPTRKLSR
HHHHHHHHHHHHCCCCEEECCCCCCEEECCCEEECCCEEEEEECHHHHCCCCCHHHHHHH
YWRTLVSPSGEGYLLESCQRGGAYFVNWLLDTFAGGRSDPAIFERLEAEAASLDVGSGGV
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
TVCSYLMGCMDPHWDADARATFSGMGPETGMGHLYRASMEAITLEFVRSLSEMKSMGVAA
HHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DRIFVIGGGAGSALWRQMIADASGLPVIRSLSNEASALGAGMSAAIGAGWYGHFGEAAGA
CEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
MSRLAEQIDPRPAAAQAWAALSRRQANLYQATRRLDAYDGP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]