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The map label for this gene is tyrC [H]

Identifier: 150397747

GI number: 150397747

Start: 2647319

End: 2648245

Strand: Reverse

Name: tyrC [H]

Synonym: Smed_2549

Alternate gene names: 150397747

Gene position: 2648245-2647319 (Counterclockwise)

Preceding gene: 150397748

Following gene: 150397745

Centisome position: 70.02

GC content: 62.46

Gene sequence:

>927_bases
ATGATGGCTCAGCAGTTCGAAACCATCGCTCTGATCGGCGTCGGTTTGATCGGATCGTCGATTGCGCGGGATATCCGTGA
GAAGCAGCTTGCCGGTCGGGTAGTGGTTACGACCCGCAGCGAAGCGACGCTGAAGCGTGCAAGCGAATTGAGCCTCGGCG
ATCTTTACACGCTTTCGGCGGCCGAGGCGGTAAAGGGCGCTGACCTCGTTATCGTGTCGGTGCCTGTCGGTGCCTCCGGG
GCGGTCGCTGCGGAAATCGCGGCCCATCTGAAACCGGGGGCGATCGTCACCGATGTCGGCTCGACCAAGGGCTCGGTCAT
CGCCCAGATGGCCCCGCATCTGCCTGAAAACGTCCATTTCGTTCCCGGCCATCCTATTGCCGGCACCGAGCACTCAGGTC
CGGATGCGGGCTTTGCGGGTCTCTTTCGTGGCCGCTGGTGCATTCTGACGCCGCCCACCGGCACGAATGACGAGGCCGTC
GCCAGGCTCAGGCTCTTCTGGGAAACGCTCGGCTCGATGGTAGACGAGATGGATCCCGAGCACCACGACAAGGTGCTGGC
GATCGTATCGCATCTTCCGCACATCATCGCTTACAATATCGTCGGCACCGCCGACGACCTCGAGACGGTGACTGAGTCCG
AGGTTATCAAATACTCGGCCTCGGGCTTTCGCGACTTCACCCGCCTCGCGGCCTCCGATCCGACCATGTGGCGCGACGTC
TGCCTGCACAACAAGGAGGCGATCCTCGAAATGCTTGCCCGCTTCTCCGAAGATCTCGCCTCTCTGCAGCGCGCGATCCG
CTGGGGCGACGGCGACAAGCTTTTCGATCTCTTCACCCGTACGCGGGCGATACGCCGCTCGATCATCCAGGCCGGTCAGG
ATACCGCTATGCCCGACTTCGGCCGGCACGCGATGGATCAGAAGTAG

Upstream 100 bases:

>100_bases
TCGGCGCCTACGGTTTTCCCAATGCGCTGAGAATGACGATAGGCACGAAAGAAGCGAACGAGGGCGTCGTTGCGGCGCTG
ACTGAATTCATGGGACGGAA

Downstream 100 bases:

>100_bases
GCCACGGCGTTCCGCTATCTGATTGAGATGCTGACGGGTTTTGGAGCGGGACGAGGAAAGGTGCGTGCGCCTTAAGGAGA
GCGGCGCCTACAGCGTCGGC

Product: cyclohexadienyl dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMAQQFETIALIGVGLIGSSIARDIREKQLAGRVVVTTRSEATLKRASELSLGDLYTLSAAEAVKGADLVIVSVPVGASG
AVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPENVHFVPGHPIAGTEHSGPDAGFAGLFRGRWCILTPPTGTNDEAV
ARLRLFWETLGSMVDEMDPEHHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDV
CLHNKEAILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIIQAGQDTAMPDFGRHAMDQK

Sequences:

>Translated_308_residues
MMAQQFETIALIGVGLIGSSIARDIREKQLAGRVVVTTRSEATLKRASELSLGDLYTLSAAEAVKGADLVIVSVPVGASG
AVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPENVHFVPGHPIAGTEHSGPDAGFAGLFRGRWCILTPPTGTNDEAV
ARLRLFWETLGSMVDEMDPEHHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDV
CLHNKEAILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIIQAGQDTAMPDFGRHAMDQK
>Mature_308_residues
MMAQQFETIALIGVGLIGSSIARDIREKQLAGRVVVTTRSEATLKRASELSLGDLYTLSAAEAVKGADLVIVSVPVGASG
AVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPENVHFVPGHPIAGTEHSGPDAGFAGLFRGRWCILTPPTGTNDEAV
ARLRLFWETLGSMVDEMDPEHHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDV
CLHNKEAILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIIQAGQDTAMPDFGRHAMDQK

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 33260; Mature: 33260

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAQQFETIALIGVGLIGSSIARDIREKQLAGRVVVTTRSEATLKRASELSLGDLYTLSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCEEEHHH
AEAVKGADLVIVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPENVHF
HHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCEE
VPGHPIAGTEHSGPDAGFAGLFRGRWCILTPPTGTNDEAVARLRLFWETLGSMVDEMDPE
CCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
HHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
CLHNKEAILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIIQAGQDTAMPDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
GRHAMDQK
HHHHCCCC
>Mature Secondary Structure
MMAQQFETIALIGVGLIGSSIARDIREKQLAGRVVVTTRSEATLKRASELSLGDLYTLSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCEEEHHH
AEAVKGADLVIVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPENVHF
HHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCEE
VPGHPIAGTEHSGPDAGFAGLFRGRWCILTPPTGTNDEAVARLRLFWETLGSMVDEMDPE
CCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
HHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
CLHNKEAILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIIQAGQDTAMPDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
GRHAMDQK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]