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The map label for this gene is glcD [H]

Identifier: 150397685

GI number: 150397685

Start: 2568934

End: 2570373

Strand: Reverse

Name: glcD [H]

Synonym: Smed_2485

Alternate gene names: 150397685

Gene position: 2570373-2568934 (Counterclockwise)

Preceding gene: 150397694

Following gene: 150397684

Centisome position: 67.97

GC content: 61.32

Gene sequence:

>1440_bases
ATGACGAGCGGAATGACGGGCGCGGTAGAGGAGCCGAGCGGCGCTGCGGTACTGCGCCGAATGCTCGGCGACGATATCGT
GCTGATCGAAAGGGAGAAGATGCTTCCCTACTGCCGCGATTGGCATGGCGATGCGGTCAGCTCCGCAGTGGCGGTGATTC
GCCCTCGCTCGACCGATCAGGTGGCGGCAGCCGTGAAGGCCTGCCGGGCGCTCGGGTTTTCGATCGTGCCGCAGGGCGGC
AATACCGGGCTGGTACTCGGCGCCATTCCCGATGCCCCGGAACGGCAGGTCGTACTTTCTCTCGAGCGCATGAACCGCAT
CCGTAAGATCGATGCGGACGACTTTTCGGCTGTTGTCGAGGCTGGCTGCATTCTTTCCGAGCTCAAGGATGCGGTCTCGG
AAAAGGGCATGTTCTTTCCGCTTGCACTCGGCGCGCAGGGGAGTTGCCGGATCGGGGGCAATGTTTCGACGAATGCCGGA
GGCGTCAACGTGCTCCGCTACGGCATGACGCGTGAACTGGTGCTTGGGCTTGAAGTGGTCCTTCCGGATGGCAGCATCCT
CGAAGGTCTTTCGACGCTGAGGAAGGACAATCGCGGTATCGATCTGAAGCAGCTCTTTATCGGTGCGGAAGGCACGCTCG
GCATCATCACCGCCGTGTCAATCAAGCTGACGCCCTATCCGGATCAGGCAGCGACCGCGCTCCTCGGCCTTGCCTCCCTG
GAAGATGCCATCAAGCTCTATCGCCGGGCTCGCCGGGACTGCTGCGACCTGATGTCGGCCTTTGAATTTATGCCGCCGCT
CGCTTTCACCTTGGCACAGGAGGCGATTTCCGACCTGCCGATCCCAATCTCGACGGAATATCCGGCCTATGTGCTGATGG
AAATCTCCGGCTCCGGCCTCGTCGATGTCGACGATCTGATGCAGCGCTTCCTTGAAGGTGTATTGGAGGAAGGGCTGGTT
CTCGACGGAACGATCGCCGCCTCGCAGACGCAGGCGCGCAATCTCTGGCTGATTCGCGAAGGGATAAACGAAGGCCAGGC
AAAGCGCGGCGCCCATATGCGCACCGATATTTCCGTGCCGCTCTCACAGCTCGCATCTTTCGTGGATGAGGCCGAAAGGG
CGGTCTCCGAGGCACTTCCGGGTGCCGTCAGCGTTTCCTATGGCCATGTCGGCGACGGCAATGTGCACCTCAACGTCCTG
CCGCCGTCAGGCAGTACACCAGAGGAGCGCATCCAGTTGATCTACAAGGCCAAGTCGGTCGTGAACGAGGTGCTCGACCG
ATATGCGGGAAGCATCAGCGCCGAGCACGGCATCGGGCGCCTGAAGCGTCCGGACTTCGATGCCAGGTTGCCCGAGACCA
GCCGAAAGCTGTTGACGGCGCTCAAGCATGCCGTTGATCCGGAGTTGATCATGAATCCTGGTTGCCAGCTGCGATTCTAG

Upstream 100 bases:

>100_bases
TGCTCTGCTTGAAAACAGGATTTTGCGGTTCGCGGAATAATCCCGGTTACGAGCGAGCACGTGGCGTTTCCCCAGGCAGC
CGCGGAGGAAGGCAGGAATT

Downstream 100 bases:

>100_bases
ATACGAACGTGATCTATTCTAATAGATGGGGCGGGATGAGAGCGGACTTTCCTCAATCTGCTCGAAGCGGGAGAAGCAAT
CTTGATGGCAACGGATTTCG

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTSGMTGAVEEPSGAAVLRRMLGDDIVLIEREKMLPYCRDWHGDAVSSAVAVIRPRSTDQVAAAVKACRALGFSIVPQGG
NTGLVLGAIPDAPERQVVLSLERMNRIRKIDADDFSAVVEAGCILSELKDAVSEKGMFFPLALGAQGSCRIGGNVSTNAG
GVNVLRYGMTRELVLGLEVVLPDGSILEGLSTLRKDNRGIDLKQLFIGAEGTLGIITAVSIKLTPYPDQAATALLGLASL
EDAIKLYRRARRDCCDLMSAFEFMPPLAFTLAQEAISDLPIPISTEYPAYVLMEISGSGLVDVDDLMQRFLEGVLEEGLV
LDGTIAASQTQARNLWLIREGINEGQAKRGAHMRTDISVPLSQLASFVDEAERAVSEALPGAVSVSYGHVGDGNVHLNVL
PPSGSTPEERIQLIYKAKSVVNEVLDRYAGSISAEHGIGRLKRPDFDARLPETSRKLLTALKHAVDPELIMNPGCQLRF

Sequences:

>Translated_479_residues
MTSGMTGAVEEPSGAAVLRRMLGDDIVLIEREKMLPYCRDWHGDAVSSAVAVIRPRSTDQVAAAVKACRALGFSIVPQGG
NTGLVLGAIPDAPERQVVLSLERMNRIRKIDADDFSAVVEAGCILSELKDAVSEKGMFFPLALGAQGSCRIGGNVSTNAG
GVNVLRYGMTRELVLGLEVVLPDGSILEGLSTLRKDNRGIDLKQLFIGAEGTLGIITAVSIKLTPYPDQAATALLGLASL
EDAIKLYRRARRDCCDLMSAFEFMPPLAFTLAQEAISDLPIPISTEYPAYVLMEISGSGLVDVDDLMQRFLEGVLEEGLV
LDGTIAASQTQARNLWLIREGINEGQAKRGAHMRTDISVPLSQLASFVDEAERAVSEALPGAVSVSYGHVGDGNVHLNVL
PPSGSTPEERIQLIYKAKSVVNEVLDRYAGSISAEHGIGRLKRPDFDARLPETSRKLLTALKHAVDPELIMNPGCQLRF
>Mature_478_residues
TSGMTGAVEEPSGAAVLRRMLGDDIVLIEREKMLPYCRDWHGDAVSSAVAVIRPRSTDQVAAAVKACRALGFSIVPQGGN
TGLVLGAIPDAPERQVVLSLERMNRIRKIDADDFSAVVEAGCILSELKDAVSEKGMFFPLALGAQGSCRIGGNVSTNAGG
VNVLRYGMTRELVLGLEVVLPDGSILEGLSTLRKDNRGIDLKQLFIGAEGTLGIITAVSIKLTPYPDQAATALLGLASLE
DAIKLYRRARRDCCDLMSAFEFMPPLAFTLAQEAISDLPIPISTEYPAYVLMEISGSGLVDVDDLMQRFLEGVLEEGLVL
DGTIAASQTQARNLWLIREGINEGQAKRGAHMRTDISVPLSQLASFVDEAERAVSEALPGAVSVSYGHVGDGNVHLNVLP
PSGSTPEERIQLIYKAKSVVNEVLDRYAGSISAEHGIGRLKRPDFDARLPETSRKLLTALKHAVDPELIMNPGCQLRF

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=435, Percent_Identity=40.4597701149425, Blast_Score=298, Evalue=9e-81,
Organism=Homo sapiens, GI37595756, Length=437, Percent_Identity=31.1212814645309, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37595754, Length=460, Percent_Identity=29.5652173913043, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4501993, Length=206, Percent_Identity=30.0970873786408, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789351, Length=458, Percent_Identity=29.0393013100437, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI48994907, Length=212, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787977, Length=509, Percent_Identity=25.7367387033399, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=466, Percent_Identity=35.1931330472103, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71992373, Length=474, Percent_Identity=29.1139240506329, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71992381, Length=474, Percent_Identity=28.4810126582279, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71992392, Length=378, Percent_Identity=31.4814814814815, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17556096, Length=472, Percent_Identity=23.728813559322, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320023, Length=451, Percent_Identity=40.5764966740577, Blast_Score=332, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6320764, Length=471, Percent_Identity=35.031847133758, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6320027, Length=432, Percent_Identity=26.8518518518519, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI18921117, Length=460, Percent_Identity=38.2608695652174, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24639277, Length=460, Percent_Identity=38.2608695652174, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24639275, Length=460, Percent_Identity=38.2608695652174, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24653753, Length=465, Percent_Identity=24.9462365591398, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51389; Mature: 51258

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGMTGAVEEPSGAAVLRRMLGDDIVLIEREKMLPYCRDWHGDAVSSAVAVIRPRSTDQ
CCCCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHCCCHHHCCCCHHHHHHHHEECCCCHHH
VAAAVKACRALGFSIVPQGGNTGLVLGAIPDAPERQVVLSLERMNRIRKIDADDFSAVVE
HHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AGCILSELKDAVSEKGMFFPLALGAQGSCRIGGNVSTNAGGVNVLRYGMTRELVLGLEVV
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCHHHHHHCCHHHHHHCEEEE
LPDGSILEGLSTLRKDNRGIDLKQLFIGAEGTLGIITAVSIKLTPYPDQAATALLGLASL
ECCCHHHHHHHHHHHCCCCCCHHHHEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHH
EDAIKLYRRARRDCCDLMSAFEFMPPLAFTLAQEAISDLPIPISTEYPAYVLMEISGSGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
VDVDDLMQRFLEGVLEEGLVLDGTIAASQTQARNLWLIREGINEGQAKRGAHMRTDISVP
CCHHHHHHHHHHHHHHCCCEEECEEECCCHHHCCEEEEECCCCCCHHHCCCCCCCCCCCC
LSQLASFVDEAERAVSEALPGAVSVSYGHVGDGNVHLNVLPPSGSTPEERIQLIYKAKSV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
VNEVLDRYAGSISAEHGIGRLKRPDFDARLPETSRKLLTALKHAVDPELIMNPGCQLRF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEECCCCCCCC
>Mature Secondary Structure 
TSGMTGAVEEPSGAAVLRRMLGDDIVLIEREKMLPYCRDWHGDAVSSAVAVIRPRSTDQ
CCCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHCCCHHHCCCCHHHHHHHHEECCCCHHH
VAAAVKACRALGFSIVPQGGNTGLVLGAIPDAPERQVVLSLERMNRIRKIDADDFSAVVE
HHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AGCILSELKDAVSEKGMFFPLALGAQGSCRIGGNVSTNAGGVNVLRYGMTRELVLGLEVV
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCHHHHHHCCHHHHHHCEEEE
LPDGSILEGLSTLRKDNRGIDLKQLFIGAEGTLGIITAVSIKLTPYPDQAATALLGLASL
ECCCHHHHHHHHHHHCCCCCCHHHHEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHH
EDAIKLYRRARRDCCDLMSAFEFMPPLAFTLAQEAISDLPIPISTEYPAYVLMEISGSGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
VDVDDLMQRFLEGVLEEGLVLDGTIAASQTQARNLWLIREGINEGQAKRGAHMRTDISVP
CCHHHHHHHHHHHHHHCCCEEECEEECCCHHHCCEEEEECCCCCCHHHCCCCCCCCCCCC
LSQLASFVDEAERAVSEALPGAVSVSYGHVGDGNVHLNVLPPSGSTPEERIQLIYKAKSV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
VNEVLDRYAGSISAEHGIGRLKRPDFDARLPETSRKLLTALKHAVDPELIMNPGCQLRF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]