Click here to switch to the map view.

The map label for this gene is cyoC [H]

Identifier: 150397628

GI number: 150397628

Start: 2506490

End: 2507212

Strand: Direct

Name: cyoC [H]

Synonym: Smed_2428

Alternate gene names: 150397628

Gene position: 2506490-2507212 (Clockwise)

Preceding gene: 150397627

Following gene: 150397629

Centisome position: 66.28

GC content: 61.13

Gene sequence:

>723_bases
ATGTCCGCACCGATCAAGAACCCCGCAGCAGAAACGGTCCCGCGCCAGCCCGGTCTGGCGGGGCTCGCAGCCGACTGGGC
CTCCGACCAGCGCACGTTCAAGGACGTCTCCTGGGGCAAGGCCATGATGTGGATCTTTCTCCTCAGCGACACCTTCGTCT
TCGGCTGCTTCCTGATCGCCTACATGGCGGCACGAATGTCTACCGCCGTTCCCTGGCCGAACCCGAGCGAGGTTTTCGCA
CTCGAGATCGGCGGAACACATATGCCGCTGATCCTGATCGCGATCATGACATTCGTCCTCATCTCCTCGAGCGGCACCAT
GGCCATGGCCGTCAACTACGGTTATCGCCGGGACCGGCGGAAGACCGCGGCACTCATGCTGCTGACGGCGCTATTCGGCG
CCGCCTTCGTCGGCATGCAGGCGTTCGAATGGTCGAAACTGATTGCCGAGGGCGTAAGACCGTGGGCCAATCCCTGGGGA
GCCGCACAATTCGGCTCTTCCTTCTTCATGATCACCGGCTTTCACGGGACCCACGTCACCTTCGGCGTGATTTTCCTGCT
GATCATCGCCCGAAAAGTCTGGCGCGGCGACTTCGAAACGGAGCGGCCCGGTTTCTTCACCAGCCGCAAGGGCCGCTACG
AGATCGTCGAGATCACCGGCCTCTATTGGCACTTCGTCGACCTGGTCTGGGTCTTCATCTTCGCATTCTTTTATCTGTGG
TGA

Upstream 100 bases:

>100_bases
CATGCTGATCGTCTGGGTGGTTCTCTTCGCTCTCTTTGCGGGATGGGCCAGCGGCGTCATCGATTTCTGCCGCCAACTGC
TGACATAGGAACCCTTGAAC

Downstream 100 bases:

>100_bases
GGGAGGGCATTCATGGCTCACGCGCAGACCCATGCGCCGCAACACGCGGCCCATACGGAGCACCGGCAGCACCCGATCAA
GCTTTACCTCGTGGTCTGGG

Product: cytochrome c oxidase subunit III

Products: ferricytochrome c; H2O

Alternate protein names: Cytochrome o ubiquinol oxidase subunit III; Ubiquinol oxidase chain C [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSAPIKNPAAETVPRQPGLAGLAADWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLIAYMAARMSTAVPWPNPSEVFA
LEIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRRKTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWANPWG
AAQFGSSFFMITGFHGTHVTFGVIFLLIIARKVWRGDFETERPGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW

Sequences:

>Translated_240_residues
MSAPIKNPAAETVPRQPGLAGLAADWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLIAYMAARMSTAVPWPNPSEVFA
LEIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRRKTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWANPWG
AAQFGSSFFMITGFHGTHVTFGVIFLLIIARKVWRGDFETERPGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW
>Mature_239_residues
SAPIKNPAAETVPRQPGLAGLAADWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLIAYMAARMSTAVPWPNPSEVFAL
EIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRRKTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWANPWGA
AQFGSSFFMITGFHGTHVTFGVIFLLIIARKVWRGDFETERPGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=155, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786633, Length=196, Percent_Identity=31.1224489795918, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833
- InterPro:   IPR014206 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 27063; Mature: 26932

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPIKNPAAETVPRQPGLAGLAADWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLIA
CCCCCCCCCHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMAARMSTAVPWPNPSEVFALEIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRR
HHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHH
KTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWANPWGAAQFGSSFFMITGFHGTHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCHHHH
FGVIFLLIIARKVWRGDFETERPGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SAPIKNPAAETVPRQPGLAGLAADWASDQRTFKDVSWGKAMMWIFLLSDTFVFGCFLIA
CCCCCCCCHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMAARMSTAVPWPNPSEVFALEIGGTHMPLILIAIMTFVLISSSGTMAMAVNYGYRRDRR
HHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHH
KTAALMLLTALFGAAFVGMQAFEWSKLIAEGVRPWANPWGAAQFGSSFFMITGFHGTHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCHHHH
FGVIFLLIIARKVWRGDFETERPGFFTSRKGRYEIVEITGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]