Click here to switch to the map view.

The map label for this gene is ureC [H]

Identifier: 150397583

GI number: 150397583

Start: 2461200

End: 2462912

Strand: Reverse

Name: ureC [H]

Synonym: Smed_2383

Alternate gene names: 150397583

Gene position: 2462912-2461200 (Counterclockwise)

Preceding gene: 150397584

Following gene: 150397582

Centisome position: 65.12

GC content: 62.76

Gene sequence:

>1713_bases
ATGTCCTACAAAATGTCGCGTGCGGCCTATGCCAACATGTTCGGTCCGACCGTGGGCGACAAGGTGCGGTTGGCCGATAC
CGAACTCTTCATCGAGGTGGAAAGGGATTTCACCACCCATGGCGAGGAGGTGAAGTTCGGGGGCGGCAAAGTCATCCGCG
ACGGCATGGGCCAAAGCCAGGTGACCCGCGAAGGCGGTGCGGTCGACACGGTGATCACCAATGCATTGATCGTCGATCAT
TGGGGGATCGTGAAGGCGGATATCGGACTGAAGGACGGGCGCATCTCGGCAATAGGGAAGGCCGGCAATCCCGACACGCA
GGCCGGTGTCACCATCATCGTCGGCCCGGGCACGGAGGTCATTGCGGGCGAGGGCAAGATCGTCACGGCGGGGGGCATGG
ACAGCCATATCCACTTCATCTGCCCGCAACAGATCGACGAGGCGCTGATGAGCGGTATCACCTGCATGCTCGGCGGCGGA
ACGGGGCCGGCGCACGGCACGCTCGCCACGACCTGCACGCCGGGCCCCTGGCACATCGCCCGCATGATTGAAGCGGCGGA
TGCCTTTCCCATGAATCTCGCCTTTGCCGGAAAGGGCAATGCGTCGCTGCCCGGCGCACTCGTGGAAATGGTGCTGGGCG
GCGCCACCTCGCTGAAGCTCCACGAGGACTGGGGCACCACACCGGCAGCCATCGATTGCTGCCTTTCGGTTGCGGACGAA
TACGACGTGCAGGTGATGATCCACACGGATACGCTGAACGAAAGCGGCTTCGTCGAGGATACGATTGCTGCGATAAAGGG
CAGGACGATCCATGCCTATCACACGGAAGGGGCTGGCGGCGGCCACGCGCCGGATATCATCAGGATCTGCGGCCAGCCGA
ACGTCATCCCGTCCTCGACCAATCCGACGCGGCCTTATACCGTGAACACGCTGGCTGAACATCTGGACATGCTGATGGTC
TGCCATCACCTGTCTCCCAGCATTCCGGAAGACATCGCCTTCGCCGAAAGCCGTATCCGCAAGGAGACTATCGCGGCGGA
AGATATCCTCCACGACATCGGCGCCTTCTCGATCATTTCTTCCGACAGCCAGGCGATGGGGCGCGTCGGCGAGGTGGCGA
TCCGCACCTGGCAGACCGCCGACAAGATGAAGCGCCAGCGTGGGCGGCTCAAGGAGGAGAGCGGCGGGAATGACAATTTC
CGCGTCAAGCGCTACATCGCCAAATACACGATCAACCCGGCGATCGCCCATGGCCTCAGCCATGAGATCGGCTCTCTCGA
AACCGGCAAGCGCGCCGATCTCGTCCTGTGGAATCCAACCTTCTTCGGCGTGAAGCCCGACATGGTGCTGCTGGGCGGAA
CGATCGCCGCAGCACCGATGGGGGATCCAAACGCCTCGATTCCCACTCCGCAGCCGGTCCATTATCGGCCAATGTTCGGC
GCCTATGGAAAGAGCCGGACCAACTCCTCGGTCACTTTCGTTTCGCAGGCCTCGCTCGATGCGGGGCTCGCCGGCAGGCT
TGGCGTCGCCAAGGCGCTCGTTGCCGTCCAGAACACCCGCGGCGGCATCGGCAAGGCGTCGATGGTCCACAACAGCCTCA
CGCCACATATCGAGGTCGACCCCGAAACCTACGAGGTTCGCGCCAACGGCGAGCTCCTCACCTGCGAGCCGGCGTCGGTA
CTGCCAATGGCGCAGCGCTATTTCTTGTTCTAG

Upstream 100 bases:

>100_bases
TGCCGCCGAGCGCCGCTATGTCGATTCGCTCGCGGCACAAGGGCGACTTCGGCGTCTTCCTCCATTCACCTCTTCAGATT
TGCCCCAGGGAGCCTGAGCC

Downstream 100 bases:

>100_bases
ATTGTTGCCCCGGAACAGAGAATGAAGCGTGCCTTCAGGTGGTTTTGCGGTTCCGTTCTATTCCTGGCGCTTGCAGTGAC
GGGCGGAGCTCTGATCCCGT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALIVDH
WGIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGG
TGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE
YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMV
CHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNF
RVKRYIAKYTINPAIAHGLSHEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG
AYGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVDPETYEVRANGELLTCEPASV
LPMAQRYFLF

Sequences:

>Translated_570_residues
MSYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALIVDH
WGIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGG
TGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE
YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMV
CHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNF
RVKRYIAKYTINPAIAHGLSHEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG
AYGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVDPETYEVRANGELLTCEPASV
LPMAQRYFLF
>Mature_569_residues
SYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALIVDHW
GIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGGT
GPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEY
DVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMVC
HHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNFR
VKRYIAKYTINPAIAHGLSHEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGA
YGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVDPETYEVRANGELLTCEPASVL
PMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60533; Mature: 60401

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQ
CCCCCCHHHHHHHCCCCCCCEEEEECEEEEEEEECCCCCCCCEEEECCCEEEECCCCCHH
VTREGGAVDTVITNALIVDHWGIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEV
HHHCCCCCHHHHHCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEE
IAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGGTGPAHGTLATTCTPGPWHIA
EECCCEEEEECCCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHH
RMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE
HHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCC
YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHEECCCCCCCCCCC
NPTRPYTVNTLAEHLDMLMVCHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIIS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
SDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNFRVKRYIAKYTINPAIAHGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHEECCHHHHHCCH
HEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG
HHCCCCCCCCCCCEEEECCEEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCEECCCCC
AYGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVD
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEC
PETYEVRANGELLTCEPASVLPMAQRYFLF
CCEEEEEECCCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
SYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQ
CCCCCHHHHHHHCCCCCCCEEEEECEEEEEEEECCCCCCCCEEEECCCEEEECCCCCHH
VTREGGAVDTVITNALIVDHWGIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEV
HHHCCCCCHHHHHCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCEE
IAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGGTGPAHGTLATTCTPGPWHIA
EECCCEEEEECCCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHH
RMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE
HHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCC
YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHEECCCCCCCCCCC
NPTRPYTVNTLAEHLDMLMVCHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIIS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
SDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNFRVKRYIAKYTINPAIAHGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHEECCHHHHHCCH
HEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG
HHCCCCCCCCCCCEEEECCEEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCEECCCCC
AYGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVD
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEC
PETYEVRANGELLTCEPASVLPMAQRYFLF
CCEEEEEECCCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA