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The map label for this gene is czcB [H]

Identifier: 150397574

GI number: 150397574

Start: 2452181

End: 2453368

Strand: Direct

Name: czcB [H]

Synonym: Smed_2374

Alternate gene names: 150397574

Gene position: 2452181-2453368 (Clockwise)

Preceding gene: 150397573

Following gene: 150397575

Centisome position: 64.84

GC content: 64.14

Gene sequence:

>1188_bases
ATGGCTCAGAAAATCCTGCCCCTCGTCGGCGCTTGTGCAGCGATTCTCATCTGCGCCCTTGTGAGCGCTTCGGCCGAGGA
GGCCGCCAAGCCGCAGCAAAAGCAGGCGCCGCCATCCATCGTCGTGACCGAAGCGAGGGAACGGTCGATCACCGACCGCG
TCATCGCCACCGGATCGATCGAGGCGGTGGACGAGATTTATGTCTCTCCCCTGGTCGAAGGTCTTGCCATCCGGTCGCTC
GATGTCGACGTCGGCGATCGCGTGGAAGAAGGCAGCACGATGGCCTCGCTCAACCAGGACGCGCTGCTCCTGCAGAGAAG
CCAGCTCGAGGCCAACCTTGCAAAGGCCGAGGCGTCGCTCGCGCAACTGCACGCCCAGCTCGCCGAGGTGACGGCCAATT
CGGAGGAGGCGACGCGTGTCGCCAACCGTGCCGTGCAGCTGTCGGAAAATGGTACCGTTTCGACGGCCGAAGCCGACCGC
TTGAAAGCGCTTGCCGCGGCCGGGCGAGCACGCGTCCGCTCGGCGGAGCAGTCGGTGAGCGTCGCAACGGCAGACATCAA
GGTGGTAAAGACGCAAATCGACGACGTCGACCTGCGCCTCGCCCGCACCGCAGTGAAGGCGCCGGTCAGCGGCATTGTCT
CGCGGAAGAACGCGAAGGTCGGTGCGATCGCCAGCGGCAGCGGCGAGCCGTTGTTCGCGATCATCCGCGACGGAGAAATC
GAGATGACGGCCGACATTGCCGAGTCCGATGTCATCAAGCTTGCCGTGGGGCAGCCCGCGACGGTCAAGCTTGCCGGCAG
CACCACCACGATCGACGGGAAGATTCGGCTGATCGCGCCGACCGTCGACCCGCAGACCCGGCTCGGCACCGTTCATATCA
GCCTGAACGATCCGTCGAAGGCACGCGCCGGCATGTACGCAAGCGCCGTCATCGTGGCGGAGCAGAAGCAGACTGTGGTT
TTGCCGCAAACAGCCGTTACATCGGAAGACGGCAAATCGATTGTCCGCAAGGTCGAAGATGGCATCGTGCGTCTGGTACC
CGTGGAAACGGGTATCCAGGACGGACAGTTCATCGAGATTCTCTCCGGCATCAAGCCCGGTGAGCAGGCGGTGGCGAAGG
CCGGTGCCTATGTGCGCGATGGCGACCGCATCAATCCGGTCGAATCCGCTGAGCCGGCAACCAACTGA

Upstream 100 bases:

>100_bases
TACGCGCGGCGCTGTAGGTGAAATAGCATGATTGCGGCCGGATATCTGCCCTGCTGGGCGTGATCGGGCGTGTTTGCTTC
AGTTTCGGGAAAACAGGCGT

Downstream 100 bases:

>100_bases
CGGGAACATGAGACCATGAATTTCTCCGCCTGGTCTATCCGCAATCCGGTCGCGCCGATCCTGGCGTTCTTCGTGCTCGT
CGTTCTGGGATGGCAGTCGT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAQKILPLVGACAAILICALVSASAEEAAKPQQKQAPPSIVVTEARERSITDRVIATGSIEAVDEIYVSPLVEGLAIRSL
DVDVGDRVEEGSTMASLNQDALLLQRSQLEANLAKAEASLAQLHAQLAEVTANSEEATRVANRAVQLSENGTVSTAEADR
LKALAAAGRARVRSAEQSVSVATADIKVVKTQIDDVDLRLARTAVKAPVSGIVSRKNAKVGAIASGSGEPLFAIIRDGEI
EMTADIAESDVIKLAVGQPATVKLAGSTTTIDGKIRLIAPTVDPQTRLGTVHISLNDPSKARAGMYASAVIVAEQKQTVV
LPQTAVTSEDGKSIVRKVEDGIVRLVPVETGIQDGQFIEILSGIKPGEQAVAKAGAYVRDGDRINPVESAEPATN

Sequences:

>Translated_395_residues
MAQKILPLVGACAAILICALVSASAEEAAKPQQKQAPPSIVVTEARERSITDRVIATGSIEAVDEIYVSPLVEGLAIRSL
DVDVGDRVEEGSTMASLNQDALLLQRSQLEANLAKAEASLAQLHAQLAEVTANSEEATRVANRAVQLSENGTVSTAEADR
LKALAAAGRARVRSAEQSVSVATADIKVVKTQIDDVDLRLARTAVKAPVSGIVSRKNAKVGAIASGSGEPLFAIIRDGEI
EMTADIAESDVIKLAVGQPATVKLAGSTTTIDGKIRLIAPTVDPQTRLGTVHISLNDPSKARAGMYASAVIVAEQKQTVV
LPQTAVTSEDGKSIVRKVEDGIVRLVPVETGIQDGQFIEILSGIKPGEQAVAKAGAYVRDGDRINPVESAEPATN
>Mature_394_residues
AQKILPLVGACAAILICALVSASAEEAAKPQQKQAPPSIVVTEARERSITDRVIATGSIEAVDEIYVSPLVEGLAIRSLD
VDVGDRVEEGSTMASLNQDALLLQRSQLEANLAKAEASLAQLHAQLAEVTANSEEATRVANRAVQLSENGTVSTAEADRL
KALAAAGRARVRSAEQSVSVATADIKVVKTQIDDVDLRLARTAVKAPVSGIVSRKNAKVGAIASGSGEPLFAIIRDGEIE
MTADIAESDVIKLAVGQPATVKLAGSTTTIDGKIRLIAPTVDPQTRLGTVHISLNDPSKARAGMYASAVIVAEQKQTVVL
PQTAVTSEDGKSIVRKVEDGIVRLVPVETGIQDGQFIEILSGIKPGEQAVAKAGAYVRDGDRINPVESAEPATN

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41179; Mature: 41048

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKILPLVGACAAILICALVSASAEEAAKPQQKQAPPSIVVTEARERSITDRVIATGSI
CCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCEEEECCHHCCCHHHEEECCCH
EAVDEIYVSPLVEGLAIRSLDVDVGDRVEEGSTMASLNQDALLLQRSQLEANLAKAEASL
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AQLHAQLAEVTANSEEATRVANRAVQLSENGTVSTAEADRLKALAAAGRARVRSAEQSVS
HHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHE
VATADIKVVKTQIDDVDLRLARTAVKAPVSGIVSRKNAKVGAIASGSGEPLFAIIRDGEI
EEEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCE
EMTADIAESDVIKLAVGQPATVKLAGSTTTIDGKIRLIAPTVDPQTRLGTVHISLNDPSK
EEEECCCCCCEEEEEECCCEEEEEECCEEEECCEEEEEEECCCCCCEEEEEEEEECCCCH
ARAGMYASAVIVAEQKQTVVLPQTAVTSEDGKSIVRKVEDGIVRLVPVETGIQDGQFIEI
HHCCCEEEEEEEECCCCEEEECCHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
LSGIKPGEQAVAKAGAYVRDGDRINPVESAEPATN
HHCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQKILPLVGACAAILICALVSASAEEAAKPQQKQAPPSIVVTEARERSITDRVIATGSI
CCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCEEEECCHHCCCHHHEEECCCH
EAVDEIYVSPLVEGLAIRSLDVDVGDRVEEGSTMASLNQDALLLQRSQLEANLAKAEASL
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AQLHAQLAEVTANSEEATRVANRAVQLSENGTVSTAEADRLKALAAAGRARVRSAEQSVS
HHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHE
VATADIKVVKTQIDDVDLRLARTAVKAPVSGIVSRKNAKVGAIASGSGEPLFAIIRDGEI
EEEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCE
EMTADIAESDVIKLAVGQPATVKLAGSTTTIDGKIRLIAPTVDPQTRLGTVHISLNDPSK
EEEECCCCCCEEEEEECCCEEEEEECCEEEECCEEEEEEECCCCCCEEEEEEEEECCCCH
ARAGMYASAVIVAEQKQTVVLPQTAVTSEDGKSIVRKVEDGIVRLVPVETGIQDGQFIEI
HHCCCEEEEEEEECCCCEEEECCHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
LSGIKPGEQAVAKAGAYVRDGDRINPVESAEPATN
HHCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]