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The map label for this gene is ycjZ [C]

Identifier: 150397550

GI number: 150397550

Start: 2424961

End: 2425857

Strand: Direct

Name: ycjZ [C]

Synonym: Smed_2350

Alternate gene names: 150397550

Gene position: 2424961-2425857 (Clockwise)

Preceding gene: 150397547

Following gene: 150397560

Centisome position: 64.12

GC content: 60.54

Gene sequence:

>897_bases
ATGTCGCGCGACGAGTTCAGTGAGATGCGAGCATTCCTCGAAGTCGCTCGGGAACGGAGTTTTACGCGAGCGGCCGCCAA
GTTGGGCGTCACCCGATCGGCCCTCAGTCATACGGTCAGGGCGCTGGAGGAACGGCTTGGCATCCGTCTCCTCTCCCGCA
CCACCCGCGACGTCGCACCCACGGCGGCCGGCGAGCGCCTTGTGGAGTGCATCGAACCTCATTTCGAGAGCATTGCCGCC
GAAATCAGCGCGATCAGTGCCCTTCGGGACAAGCCCGCGGGCCACATCCGCATCGTGTGCCCCGATGACGCCATCGGCAT
GGTATTTCGCCCCAGATTGCCAGCGTTTCTGCGCGACTACCCGGACATCAAGGTGGAACTCATTGCCGACAACGGTTTTA
CGAATATCGTCGAGCGCCAGTTTGATGCCGGCGTTCGGCTTGGCGAGGCAATCGCGCGCGACATGGTGGCAGTTAGGATC
GGTCCCGATGTCCGCTATGCCGTGGTCGGCTCACCCGATTATTTCGGGCGTCATTCCACGCCGAGCAGCCCGCAGGAACT
GACCAACCACAAGTGCATCAACCTGCGGCTGCCAACGTTGGGCGCGATATATGCCTGGGAGTTCAACAAAGACGCACACG
AATTCAGCGTCCGGGTGGATGGCCAACTGACCCTGAACAATATCGAGCCGGCGCTCGATGCGGCCCTCGATGGCATAGGG
TTGGCTTATGCCCCGAAAGATCTTGTCCAGCCATACCTTGAGAGTGGTCAACTTCAGGAGGTCCTCGCGGACTGGTGCCC
GACCTTCCAGGGCTATCATCTCTATTATCCCAGCCGGCGAAATCCCTCGCCTGCGTTCTCCGCTTTCGTCGAAGCCTTCC
GATACCGATCTAAGTAG

Upstream 100 bases:

>100_bases
GCCATGTTGTGCCTCCAATTCACTTCGGGACTAGATAGCCAGACTGGCCTTGGCAGACTAGAAGCTATAATCTGCATGTT
GTAGTGAATGGGATTCACCA

Downstream 100 bases:

>100_bases
CTTGCCCGGAATTGAAGGGGGCAGTTCGGTAACCAGCCCCGAACGCAAGACAGCCAGTGCCGAGGGAAGGGCACTGGCTG
AGCTTAGGCAACTCACTGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSRDEFSEMRAFLEVARERSFTRAAAKLGVTRSALSHTVRALEERLGIRLLSRTTRDVAPTAAGERLVECIEPHFESIAA
EISAISALRDKPAGHIRIVCPDDAIGMVFRPRLPAFLRDYPDIKVELIADNGFTNIVERQFDAGVRLGEAIARDMVAVRI
GPDVRYAVVGSPDYFGRHSTPSSPQELTNHKCINLRLPTLGAIYAWEFNKDAHEFSVRVDGQLTLNNIEPALDAALDGIG
LAYAPKDLVQPYLESGQLQEVLADWCPTFQGYHLYYPSRRNPSPAFSAFVEAFRYRSK

Sequences:

>Translated_298_residues
MSRDEFSEMRAFLEVARERSFTRAAAKLGVTRSALSHTVRALEERLGIRLLSRTTRDVAPTAAGERLVECIEPHFESIAA
EISAISALRDKPAGHIRIVCPDDAIGMVFRPRLPAFLRDYPDIKVELIADNGFTNIVERQFDAGVRLGEAIARDMVAVRI
GPDVRYAVVGSPDYFGRHSTPSSPQELTNHKCINLRLPTLGAIYAWEFNKDAHEFSVRVDGQLTLNNIEPALDAALDGIG
LAYAPKDLVQPYLESGQLQEVLADWCPTFQGYHLYYPSRRNPSPAFSAFVEAFRYRSK
>Mature_297_residues
SRDEFSEMRAFLEVARERSFTRAAAKLGVTRSALSHTVRALEERLGIRLLSRTTRDVAPTAAGERLVECIEPHFESIAAE
ISAISALRDKPAGHIRIVCPDDAIGMVFRPRLPAFLRDYPDIKVELIADNGFTNIVERQFDAGVRLGEAIARDMVAVRIG
PDVRYAVVGSPDYFGRHSTPSSPQELTNHKCINLRLPTLGAIYAWEFNKDAHEFSVRVDGQLTLNNIEPALDAALDGIGL
AYAPKDLVQPYLESGQLQEVLADWCPTFQGYHLYYPSRRNPSPAFSAFVEAFRYRSK

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=46.9594594594595, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=38.4083044982699, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=28.7671232876712, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=274, Percent_Identity=28.1021897810219, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=30.3754266211604, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=27.3037542662116, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=26.3333333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=25.085910652921, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=23.7113402061856, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790011, Length=278, Percent_Identity=25.8992805755396, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=122, Percent_Identity=31.1475409836066, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786713, Length=265, Percent_Identity=26.0377358490566, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI145693105, Length=151, Percent_Identity=27.1523178807947, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=145, Percent_Identity=31.7241379310345, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=267, Percent_Identity=27.7153558052434, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=137, Percent_Identity=32.1167883211679, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33279; Mature: 33148

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDEFSEMRAFLEVARERSFTRAAAKLGVTRSALSHTVRALEERLGIRLLSRTTRDVAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TAAGERLVECIEPHFESIAAEISAISALRDKPAGHIRIVCPDDAIGMVFRPRLPAFLRDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCCHHHCCC
PDIKVELIADNGFTNIVERQFDAGVRLGEAIARDMVAVRIGPDVRYAVVGSPDYFGRHST
CCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCEEEEEECCCCCCCCCCC
PSSPQELTNHKCINLRLPTLGAIYAWEFNKDAHEFSVRVDGQLTLNNIEPALDAALDGIG
CCCHHHHCCCCEEEEECCCCCEEEEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHCCC
LAYAPKDLVQPYLESGQLQEVLADWCPTFQGYHLYYPSRRNPSPAFSAFVEAFRYRSK
CCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRDEFSEMRAFLEVARERSFTRAAAKLGVTRSALSHTVRALEERLGIRLLSRTTRDVAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TAAGERLVECIEPHFESIAAEISAISALRDKPAGHIRIVCPDDAIGMVFRPRLPAFLRDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCCHHHCCC
PDIKVELIADNGFTNIVERQFDAGVRLGEAIARDMVAVRIGPDVRYAVVGSPDYFGRHST
CCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCEEEEEECCCCCCCCCCC
PSSPQELTNHKCINLRLPTLGAIYAWEFNKDAHEFSVRVDGQLTLNNIEPALDAALDGIG
CCCHHHHCCCCEEEEECCCCCEEEEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHCCC
LAYAPKDLVQPYLESGQLQEVLADWCPTFQGYHLYYPSRRNPSPAFSAFVEAFRYRSK
CCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]