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The map label for this gene is 150397397

Identifier: 150397397

GI number: 150397397

Start: 2273420

End: 2274967

Strand: Reverse

Name: 150397397

Synonym: Smed_2196

Alternate gene names: NA

Gene position: 2274967-2273420 (Counterclockwise)

Preceding gene: 150397398

Following gene: 150397386

Centisome position: 60.15

GC content: 64.47

Gene sequence:

>1548_bases
ATGATGGCTGAGGAATGCGCAGTTGCTGCTTCGAGACGGTCCGGCGGACGGGCGGCGCGCGTTGCGCTCCGCTCGGCTCC
GCTCGCCGAAAATATCCGTCCCGTCCGGCCGGGTCTTTCCGGCGGGCAGTACAAGCCGCTGACGGAGGCAAACGTCAAAC
GAATTCACGAGGCAGCGCTCGATGCGCTGGAGCAGATCGGCCTTGCCAATGCGCCGCAATCCGGCGTCGAGATCATGACC
GGAGCCGGGGCGATCCTCGGCGAGGACGGGCGGCTCCGCTTTCCGCGTGCATTGGTCGAGGACATGCTGGCCCTCGCCGC
GCGCGACATAACGCTTTTCGCGCGTGATCCGAAACAGGACCTCGAACTCAGCGGTACGCGTGTCTATTACGGTACGGCGG
GCGCGGCGGTCCACGTCGTCGACGTCGAAAAGCGCGAATACCGCGAGTCCACCGCCAAGGACCTCCTGAACGCGGCGCAG
CTCGTCCACCGCCTGGACAATGTCCACTTCTTCCAGCGCGCCATGGTCTGCCGGGACGTTTCCGACAATTTCCTGATGGA
TATCAATACGCTCTACGCCTGCTGCGCCGGAACGACGAAGCATGTCGGCACGAGCTTCTCCGATCCGTCGCATGTCGAGG
GCTGCTTCGATCTCATTCACATGATAGCCGGCGGCGAGGAGCAGTGGCGGGCGCGGCCTTTCGTCTCGAACTCGAACTGC
TTCGTGGTGCCTCCGATGAAGTTCGCGGAGGAAAGCTGCATCACCATGGAGAAGTGCATCCGCGGCGGCATGCCGATCCT
TCTGCTTTCTGCGGGCCAGGCGGGGGCGACTGCCCCGGCCCCGCTTGCAACCGCCATCGTACAGGCGGTGGCCGAGTGCC
TTGCGGGCGTCGTCTACGTCAACGCTCTTTCGCCCGGTCATCCGGCTGTCTTCGGTACGTGGCCGTTCGTCTCCGATCTG
AGAACGGGTGCGATGTCGGGCGGTTCCGGCGAGCAGGCGTTGCTATCGGCGGGTTGTGCGCAGATGCACCAGTTCTACCG
TCTCCCGGGCGGCGCTGCTGCCGGCATTGCGGATGCGAAGCTTCCCGATATGCAGGCGGGCTGGGAACAGGCGATCTCCA
ATGTCATGGCGGGGCTTTCCGGCCTGAACATGGTCTATGAGTCCGTCGGCATGCACGCCTCGCTCCTGGGCTTTTGCCTG
GAGTCGCTGGTGCTGGGTGACGACATGCTGGGCCAGGTGCAGCGCTGCATCCGCGGCATCGATGTCACGGAGGATACAGT
CTCGCTCGAAACCATGCGCTCGGTCTGCCTCGACGGCCCCGGCCACTATCTTGGCCATCCGCAGACACTTGGCCTGATGC
AGACGGAATATATCTATCCGGCGGTTGCCGACCGCACGAGCCCCAAGGAATGGGTCGAGATCGGCCGGCCGGATCTCGTC
GCGCGCGCGATCGAAAGGAAGAACCGCATTCTTGCCGAGGCCGCCCCGTCGCTGATCGCGCCGGAGGTCGATCGGTCGAT
CCGGGAGCGGTTCGGGATATATTGCTGA

Upstream 100 bases:

>100_bases
TTGACGGGGAGATGGGAACATACGGCGCCCTCTGAAACCATCCGGGGAGAGGGCAGGCGAGGGGCGATTGCCACACGACG
ACAGCGCCATTGGGAGATGA

Downstream 100 bases:

>100_bases
GACGATCGTCCATGCGGTTGGCGGCAGCGAACGGCTCCTGCATCTGCGAGATGGAATGTTTCGGCGGCAAATTCAGGCGA
GACCGCTTGAACAAATTTAC

Product: trimethylamine methyltransferase

Products: NA

Alternate protein names: TMA methyltransferase [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MMAEECAVAASRRSGGRAARVALRSAPLAENIRPVRPGLSGGQYKPLTEANVKRIHEAALDALEQIGLANAPQSGVEIMT
GAGAILGEDGRLRFPRALVEDMLALAARDITLFARDPKQDLELSGTRVYYGTAGAAVHVVDVEKREYRESTAKDLLNAAQ
LVHRLDNVHFFQRAMVCRDVSDNFLMDINTLYACCAGTTKHVGTSFSDPSHVEGCFDLIHMIAGGEEQWRARPFVSNSNC
FVVPPMKFAEESCITMEKCIRGGMPILLLSAGQAGATAPAPLATAIVQAVAECLAGVVYVNALSPGHPAVFGTWPFVSDL
RTGAMSGGSGEQALLSAGCAQMHQFYRLPGGAAAGIADAKLPDMQAGWEQAISNVMAGLSGLNMVYESVGMHASLLGFCL
ESLVLGDDMLGQVQRCIRGIDVTEDTVSLETMRSVCLDGPGHYLGHPQTLGLMQTEYIYPAVADRTSPKEWVEIGRPDLV
ARAIERKNRILAEAAPSLIAPEVDRSIRERFGIYC

Sequences:

>Translated_515_residues
MMAEECAVAASRRSGGRAARVALRSAPLAENIRPVRPGLSGGQYKPLTEANVKRIHEAALDALEQIGLANAPQSGVEIMT
GAGAILGEDGRLRFPRALVEDMLALAARDITLFARDPKQDLELSGTRVYYGTAGAAVHVVDVEKREYRESTAKDLLNAAQ
LVHRLDNVHFFQRAMVCRDVSDNFLMDINTLYACCAGTTKHVGTSFSDPSHVEGCFDLIHMIAGGEEQWRARPFVSNSNC
FVVPPMKFAEESCITMEKCIRGGMPILLLSAGQAGATAPAPLATAIVQAVAECLAGVVYVNALSPGHPAVFGTWPFVSDL
RTGAMSGGSGEQALLSAGCAQMHQFYRLPGGAAAGIADAKLPDMQAGWEQAISNVMAGLSGLNMVYESVGMHASLLGFCL
ESLVLGDDMLGQVQRCIRGIDVTEDTVSLETMRSVCLDGPGHYLGHPQTLGLMQTEYIYPAVADRTSPKEWVEIGRPDLV
ARAIERKNRILAEAAPSLIAPEVDRSIRERFGIYC
>Mature_515_residues
MMAEECAVAASRRSGGRAARVALRSAPLAENIRPVRPGLSGGQYKPLTEANVKRIHEAALDALEQIGLANAPQSGVEIMT
GAGAILGEDGRLRFPRALVEDMLALAARDITLFARDPKQDLELSGTRVYYGTAGAAVHVVDVEKREYRESTAKDLLNAAQ
LVHRLDNVHFFQRAMVCRDVSDNFLMDINTLYACCAGTTKHVGTSFSDPSHVEGCFDLIHMIAGGEEQWRARPFVSNSNC
FVVPPMKFAEESCITMEKCIRGGMPILLLSAGQAGATAPAPLATAIVQAVAECLAGVVYVNALSPGHPAVFGTWPFVSDL
RTGAMSGGSGEQALLSAGCAQMHQFYRLPGGAAAGIADAKLPDMQAGWEQAISNVMAGLSGLNMVYESVGMHASLLGFCL
ESLVLGDDMLGQVQRCIRGIDVTEDTVSLETMRSVCLDGPGHYLGHPQTLGLMQTEYIYPAVADRTSPKEWVEIGRPDLV
ARAIERKNRILAEAAPSLIAPEVDRSIRERFGIYC

Specific function: Catalyzes probably the transfer of a methyl group from trimethylamine to the corrinoid cofactor of mttC [H]

COG id: COG5598

COG function: function code H; Trimethylamine:corrinoid methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010426 [H]

Pfam domain/function: PF06253 MTTB [H]

EC number: NA

Molecular weight: Translated: 55204; Mature: 55204

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAEECAVAASRRSGGRAARVALRSAPLAENIRPVRPGLSGGQYKPLTEANVKRIHEAAL
CCCHHHHHHHHHCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DALEQIGLANAPQSGVEIMTGAGAILGEDGRLRFPRALVEDMLALAARDITLFARDPKQD
HHHHHCCCCCCCCCCCEEEECCCCEECCCCCEECCHHHHHHHHHHHHHCEEEEECCCHHC
LELSGTRVYYGTAGAAVHVVDVEKREYRESTAKDLLNAAQLVHRLDNVHFFQRAMVCRDV
CCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDNFLMDINTLYACCAGTTKHVGTSFSDPSHVEGCFDLIHMIAGGEEQWRARPFVSNSNC
CCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCE
FVVPPMKFAEESCITMEKCIRGGMPILLLSAGQAGATAPAPLATAIVQAVAECLAGVVYV
EEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NALSPGHPAVFGTWPFVSDLRTGAMSGGSGEQALLSAGCAQMHQFYRLPGGAAAGIADAK
CCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPDMQAGWEQAISNVMAGLSGLNMVYESVGMHASLLGFCLESLVLGDDMLGQVQRCIRGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
DVTEDTVSLETMRSVCLDGPGHYLGHPQTLGLMQTEYIYPAVADRTSPKEWVEIGRPDLV
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHCHHHHCCCCHHHHHHCCCHHHH
ARAIERKNRILAEAAPSLIAPEVDRSIRERFGIYC
HHHHHHHHHHHHHHCCCHHCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMAEECAVAASRRSGGRAARVALRSAPLAENIRPVRPGLSGGQYKPLTEANVKRIHEAAL
CCCHHHHHHHHHCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DALEQIGLANAPQSGVEIMTGAGAILGEDGRLRFPRALVEDMLALAARDITLFARDPKQD
HHHHHCCCCCCCCCCCEEEECCCCEECCCCCEECCHHHHHHHHHHHHHCEEEEECCCHHC
LELSGTRVYYGTAGAAVHVVDVEKREYRESTAKDLLNAAQLVHRLDNVHFFQRAMVCRDV
CCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDNFLMDINTLYACCAGTTKHVGTSFSDPSHVEGCFDLIHMIAGGEEQWRARPFVSNSNC
CCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCE
FVVPPMKFAEESCITMEKCIRGGMPILLLSAGQAGATAPAPLATAIVQAVAECLAGVVYV
EEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NALSPGHPAVFGTWPFVSDLRTGAMSGGSGEQALLSAGCAQMHQFYRLPGGAAAGIADAK
CCCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPDMQAGWEQAISNVMAGLSGLNMVYESVGMHASLLGFCLESLVLGDDMLGQVQRCIRGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
DVTEDTVSLETMRSVCLDGPGHYLGHPQTLGLMQTEYIYPAVADRTSPKEWVEIGRPDLV
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHCHHHHCCCCHHHHHHCCCHHHH
ARAIERKNRILAEAAPSLIAPEVDRSIRERFGIYC
HHHHHHHHHHHHHHCCCHHCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA