Click here to switch to the map view.

The map label for this gene is glxA [H]

Identifier: 150397373

GI number: 150397373

Start: 2242627

End: 2243616

Strand: Reverse

Name: glxA [H]

Synonym: Smed_2172

Alternate gene names: 150397373

Gene position: 2243616-2242627 (Counterclockwise)

Preceding gene: 150397383

Following gene: 150397367

Centisome position: 59.33

GC content: 62.83

Gene sequence:

>990_bases
ATGGGAGGAAGTTTCGGCGTGGACAGCAGCACTTCGCAAGCGCAGCATCTCGATCTGCTGATATTGCCGGAGACCAATCT
CATTCTTGTCGCTTCGGTGGTCGAGCCCTTACGCGCCGCCAATCGGATAGCCGGGCGCCCGCTTTACAGCTGGGCCCTGT
TCAGCCCTGACGGAAATGCGATCGAGACGAAAAGCGGCATTCCCATTCCGGTGGCCGGGGCCTTCCGTCCGCAGCGCGAG
ACTGCGCCGCTCTTCGTGCTTTCCAGCTACCACTGGCAGCGCAGCGCCACCGTGCAGCTCAAGATGTTCCTGTCGCAGAC
GGCGCGGCACAGGGAGACGATGGCGGGAATCGAATCCGGCTCCTGGCTCCTTGCGGAGGCGAGCCTCCTCGACAATTTCT
CGGCCACCACCCATTGGGAGGACTTCGAGGACTTCTCGGCCGCCTATCCGCAGGTCACGATGGTGCGCGACCGGTTCGTC
ATCGACCGCAAGCGCATTACCACCGGCGGCTCGCTGCCGACGCTGGATCTGATGCTGGAACTGATCCGCCGCGCGCACGG
CTACTCGCTGGCACTCGAAGTATCCCGCCTCTTCATTTACGAGCAGGAGCGCACGCGCGGGGACCTCCTGCAGGTGCCGG
CCATCGGCAATATGCGCATTCTGGATGCGCGGGTCGGTGCAGCGGTAAAGCTTATGGAGGAGACGGTAGAGGCACCGCTG
ACACTCGCCCGGCTGGCGCGCCGGGCAGGCATCAGTGCCCGGCATCTGCAGGATCTCTTCAAGGAGACGATGGGTGTCGC
TCCGCACGAGCACTATCTGGCGCTCCGGCTCAACGCGGCGCGTCGCAAGGTGATCGAGACGCGGATGGCGTTCGCCGATA
TCGCGGCGATTTCCGGCTTCAATTCCTCGTCTTCATTTTCCCGCAGCTATAGGGCTCATTATCGAGAAAGCCCAAGTGAG
ACACGCCGGCGGCTCAAGTTGAAGAACTGA

Upstream 100 bases:

>100_bases
GAGCGGCATTGATGTCCTCCCTTTCGTTGCCTGCATTACGAGCCAGAAAGCGCCGGACTGCTTTTCAGAAACAGAAGCAA
TCTATACAGTATCGGAAAGG

Downstream 100 bases:

>100_bases
TTCAAGAGCTTCAGGCTGCAGTTCAGAAAGAATGGTTTCACGAATCGAATCAAAGACCTGCCGCCGTTCCGTCGAGAAGT
GATTCAGTGCGCGGGCGCGA

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGGSFGVDSSTSQAQHLDLLILPETNLILVASVVEPLRAANRIAGRPLYSWALFSPDGNAIETKSGIPIPVAGAFRPQRE
TAPLFVLSSYHWQRSATVQLKMFLSQTARHRETMAGIESGSWLLAEASLLDNFSATTHWEDFEDFSAAYPQVTMVRDRFV
IDRKRITTGGSLPTLDLMLELIRRAHGYSLALEVSRLFIYEQERTRGDLLQVPAIGNMRILDARVGAAVKLMEETVEAPL
TLARLARRAGISARHLQDLFKETMGVAPHEHYLALRLNAARRKVIETRMAFADIAAISGFNSSSSFSRSYRAHYRESPSE
TRRRLKLKN

Sequences:

>Translated_329_residues
MGGSFGVDSSTSQAQHLDLLILPETNLILVASVVEPLRAANRIAGRPLYSWALFSPDGNAIETKSGIPIPVAGAFRPQRE
TAPLFVLSSYHWQRSATVQLKMFLSQTARHRETMAGIESGSWLLAEASLLDNFSATTHWEDFEDFSAAYPQVTMVRDRFV
IDRKRITTGGSLPTLDLMLELIRRAHGYSLALEVSRLFIYEQERTRGDLLQVPAIGNMRILDARVGAAVKLMEETVEAPL
TLARLARRAGISARHLQDLFKETMGVAPHEHYLALRLNAARRKVIETRMAFADIAAISGFNSSSSFSRSYRAHYRESPSE
TRRRLKLKN
>Mature_328_residues
GGSFGVDSSTSQAQHLDLLILPETNLILVASVVEPLRAANRIAGRPLYSWALFSPDGNAIETKSGIPIPVAGAFRPQRET
APLFVLSSYHWQRSATVQLKMFLSQTARHRETMAGIESGSWLLAEASLLDNFSATTHWEDFEDFSAAYPQVTMVRDRFVI
DRKRITTGGSLPTLDLMLELIRRAHGYSLALEVSRLFIYEQERTRGDLLQVPAIGNMRILDARVGAAVKLMEETVEAPLT
LARLARRAGISARHLQDLFKETMGVAPHEHYLALRLNAARRKVIETRMAFADIAAISGFNSSSSFSRSYRAHYRESPSET
RRRLKLKN

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36769; Mature: 36637

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGSFGVDSSTSQAQHLDLLILPETNLILVASVVEPLRAANRIAGRPLYSWALFSPDGNA
CCCCCCCCCCCCCHHHEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
IETKSGIPIPVAGAFRPQRETAPLFVLSSYHWQRSATVQLKMFLSQTARHRETMAGIESG
EECCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SWLLAEASLLDNFSATTHWEDFEDFSAAYPQVTMVRDRFVIDRKRITTGGSLPTLDLMLE
CEEEEEHHHHHCCCCCCCCCCHHHHHHCCCEEEEEHHHHHEEHHEECCCCCCCHHHHHHH
LIRRAHGYSLALEVSRLFIYEQERTRGDLLQVPAIGNMRILDARVGAAVKLMEETVEAPL
HHHHHCCCEEEEEEEHHEEEECCCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHH
TLARLARRAGISARHLQDLFKETMGVAPHEHYLALRLNAARRKVIETRMAFADIAAISGF
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCC
NSSSSFSRSYRAHYRESPSETRRRLKLKN
CCCCHHHHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure 
GGSFGVDSSTSQAQHLDLLILPETNLILVASVVEPLRAANRIAGRPLYSWALFSPDGNA
CCCCCCCCCCCCHHHEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
IETKSGIPIPVAGAFRPQRETAPLFVLSSYHWQRSATVQLKMFLSQTARHRETMAGIESG
EECCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SWLLAEASLLDNFSATTHWEDFEDFSAAYPQVTMVRDRFVIDRKRITTGGSLPTLDLMLE
CEEEEEHHHHHCCCCCCCCCCHHHHHHCCCEEEEEHHHHHEEHHEECCCCCCCHHHHHHH
LIRRAHGYSLALEVSRLFIYEQERTRGDLLQVPAIGNMRILDARVGAAVKLMEETVEAPL
HHHHHCCCEEEEEEEHHEEEECCCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHH
TLARLARRAGISARHLQDLFKETMGVAPHEHYLALRLNAARRKVIETRMAFADIAAISGF
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCC
NSSSSFSRSYRAHYRESPSETRRRLKLKN
CCCCHHHHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]