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The map label for this gene is ykvY [H]

Identifier: 150397342

GI number: 150397342

Start: 2209241

End: 2210374

Strand: Direct

Name: ykvY [H]

Synonym: Smed_2141

Alternate gene names: 150397342

Gene position: 2209241-2210374 (Clockwise)

Preceding gene: 150397341

Following gene: 150397348

Centisome position: 58.42

GC content: 61.46

Gene sequence:

>1134_bases
ATGGCGAATTATCCGGCGATCACCAGTACGGAGCGCCAAACGCGCATATCCCGTTTGCGGGCCACTCTTTCGGAGCGGAA
CGTCGGCGGGCTCCTGCTGGGTTCTACGGAAAGTCTCCGCTACTATACAGGGCTGGAGTGGCACGCCAGCGAACGGTTCC
TCGGCGCTCTCATCACGGGTTCCGACCTGATCTATATCGCCCCCGCGTTCGAGCTGAGCCGGGTCGAGACCCTGTCACGC
GAACCAGGTGAAATCCGCGCATGGCAGGAGGAGGAAAGCAGTGCCGCCCTCGTCGCATCGCTTCTGCCTCCTGAGGCGAC
ACTCGCTGTCGATGATTCACTGCCGTTGTTTGCGTATAACGCTCTGGTGGGGGAAATTGCGGCCCGCAGGCTGATTGACG
GAGGTCCGCTTATCCGTGCCCAACGAAGGTTGAAATCTGCGGCCGAGATCGAGATCATCCAGTTCGCGATGAACCTGACC
CTGGAGGTGCATCGGCGCGCGCATAAGTTCATCAAACCTGGGATTTCAGCGTCGGAGGTCAGGCGCTACATCGACGATCA
GCATCGGCTGCTCGGCGCTCCAGGCGGCTCCAGTTTCTGTATCGTCTCCTTCGGAGATGCGACTGCGCTGCCCCATGGGG
CGGAGGGGGAACAGGTCTACAAGCCCGGCGACGTGGTGCTGGTCGACACCGGCTGCCGCATTGGCGGCTACCACTCGGAC
CTGACCCGGACCTATATGATCGATGACCCGACGCCCGAATTCGCTCGTATTTGGGCTATCGAGAGGGAAGCTCAGCTGGC
CGTGTTCGAAGCTGCTCACATCGGAGCCACATGCGGCAGCCTTGATTCGGCTGCCCGAGACGTTCTCGTTCGCAACGGGC
TCGGGCCGGACTACAAACTCCCGGGTCTTCCTCACCGCGCCGGGCACGGGATCGGCCTCGAAATTCACGAGGAGCCATAT
ATTGTCCGCAGTAATCACTTCGCCCTCTCCGAAGGTATGTGCTTCTCGGTCGAGCCTATGATCGTCGTTCCGGAAGCGTT
CGGCGTTCGCCTCGAGGACCACATCTACATGAGCAAAGACGGCCCCGTCTGGTTTACGGCGCCCGCCGAAGGCCCCACCG
AGCCGTTCGCTTGA

Upstream 100 bases:

>100_bases
CGCGAGGTTCGGCACTTCGTCAACGCCCCAATATCTTGTCGACAACCTGAATCCAAATCGCTTAGTAATGTCCCTCCACC
CTTGTTGAGCGGAGTCCAGG

Downstream 100 bases:

>100_bases
TCGCAACAATGCCCTTCCAGCGCGCTCAACAGGCCAGAGAGCGCTCGGTTTCCGGATCGAAGAGATGCATCTGGTTCATG
TTGATTGAGAACGGAAGTCT

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MANYPAITSTERQTRISRLRATLSERNVGGLLLGSTESLRYYTGLEWHASERFLGALITGSDLIYIAPAFELSRVETLSR
EPGEIRAWQEEESSAALVASLLPPEATLAVDDSLPLFAYNALVGEIAARRLIDGGPLIRAQRRLKSAAEIEIIQFAMNLT
LEVHRRAHKFIKPGISASEVRRYIDDQHRLLGAPGGSSFCIVSFGDATALPHGAEGEQVYKPGDVVLVDTGCRIGGYHSD
LTRTYMIDDPTPEFARIWAIEREAQLAVFEAAHIGATCGSLDSAARDVLVRNGLGPDYKLPGLPHRAGHGIGLEIHEEPY
IVRSNHFALSEGMCFSVEPMIVVPEAFGVRLEDHIYMSKDGPVWFTAPAEGPTEPFA

Sequences:

>Translated_377_residues
MANYPAITSTERQTRISRLRATLSERNVGGLLLGSTESLRYYTGLEWHASERFLGALITGSDLIYIAPAFELSRVETLSR
EPGEIRAWQEEESSAALVASLLPPEATLAVDDSLPLFAYNALVGEIAARRLIDGGPLIRAQRRLKSAAEIEIIQFAMNLT
LEVHRRAHKFIKPGISASEVRRYIDDQHRLLGAPGGSSFCIVSFGDATALPHGAEGEQVYKPGDVVLVDTGCRIGGYHSD
LTRTYMIDDPTPEFARIWAIEREAQLAVFEAAHIGATCGSLDSAARDVLVRNGLGPDYKLPGLPHRAGHGIGLEIHEEPY
IVRSNHFALSEGMCFSVEPMIVVPEAFGVRLEDHIYMSKDGPVWFTAPAEGPTEPFA
>Mature_376_residues
ANYPAITSTERQTRISRLRATLSERNVGGLLLGSTESLRYYTGLEWHASERFLGALITGSDLIYIAPAFELSRVETLSRE
PGEIRAWQEEESSAALVASLLPPEATLAVDDSLPLFAYNALVGEIAARRLIDGGPLIRAQRRLKSAAEIEIIQFAMNLTL
EVHRRAHKFIKPGISASEVRRYIDDQHRLLGAPGGSSFCIVSFGDATALPHGAEGEQVYKPGDVVLVDTGCRIGGYHSDL
TRTYMIDDPTPEFARIWAIEREAQLAVFEAAHIGATCGSLDSAARDVLVRNGLGPDYKLPGLPHRAGHGIGLEIHEEPYI
VRSNHFALSEGMCFSVEPMIVVPEAFGVRLEDHIYMSKDGPVWFTAPAEGPTEPFA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=254, Percent_Identity=26.3779527559055, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1788728, Length=225, Percent_Identity=32.8888888888889, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789275, Length=260, Percent_Identity=27.3076923076923, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786364, Length=211, Percent_Identity=26.0663507109005, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 41234; Mature: 41103

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYPAITSTERQTRISRLRATLSERNVGGLLLGSTESLRYYTGLEWHASERFLGALITG
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCEEECCCCEEEEEEEC
SDLIYIAPAFELSRVETLSREPGEIRAWQEEESSAALVASLLPPEATLAVDDSLPLFAYN
CCEEEEECCCHHHHHHHHCCCCCCEECCCCCCCCCEEHHHHCCCCEEEEECCCCCHHHHH
ALVGEIAARRLIDGGPLIRAQRRLKSAAEIEIIQFAMNLTLEVHRRAHKFIKPGISASEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
RRYIDDQHRLLGAPGGSSFCIVSFGDATALPHGAEGEQVYKPGDVVLVDTGCRIGGYHSD
HHHHCCHHEEEECCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCC
LTRTYMIDDPTPEFARIWAIEREAQLAVFEAAHIGATCGSLDSAARDVLVRNGLGPDYKL
CEEEEEECCCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGLPHRAGHGIGLEIHEEPYIVRSNHFALSEGMCFSVEPMIVVPEAFGVRLEDHIYMSKD
CCCCCCCCCCCCEEECCCCEEEECCCEEECCCCEEECCCEEEECHHHCCEEEEEEEECCC
GPVWFTAPAEGPTEPFA
CCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANYPAITSTERQTRISRLRATLSERNVGGLLLGSTESLRYYTGLEWHASERFLGALITG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCEEECCCCEEEEEEEC
SDLIYIAPAFELSRVETLSREPGEIRAWQEEESSAALVASLLPPEATLAVDDSLPLFAYN
CCEEEEECCCHHHHHHHHCCCCCCEECCCCCCCCCEEHHHHCCCCEEEEECCCCCHHHHH
ALVGEIAARRLIDGGPLIRAQRRLKSAAEIEIIQFAMNLTLEVHRRAHKFIKPGISASEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
RRYIDDQHRLLGAPGGSSFCIVSFGDATALPHGAEGEQVYKPGDVVLVDTGCRIGGYHSD
HHHHCCHHEEEECCCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCC
LTRTYMIDDPTPEFARIWAIEREAQLAVFEAAHIGATCGSLDSAARDVLVRNGLGPDYKL
CEEEEEECCCCCCCEEEEEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGLPHRAGHGIGLEIHEEPYIVRSNHFALSEGMCFSVEPMIVVPEAFGVRLEDHIYMSKD
CCCCCCCCCCCCEEECCCCEEEECCCEEECCCCEEECCCEEEECHHHCCEEEEEEEECCC
GPVWFTAPAEGPTEPFA
CCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]