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The map label for this gene is murG [H]

Identifier: 150397283

GI number: 150397283

Start: 2138828

End: 2139952

Strand: Reverse

Name: murG [H]

Synonym: Smed_2082

Alternate gene names: 150397283

Gene position: 2139952-2138828 (Counterclockwise)

Preceding gene: 150397284

Following gene: 150397282

Centisome position: 56.58

GC content: 64.27

Gene sequence:

>1125_bases
ATGGATAAAGGCATAATTCTACTTGCCGCCGGCGGGACCGGCGGACACCTCTTTCCAGCCGAGGCGCTTGCCCACGAGTT
GAAGGCGTCCGGCTATTCCGTGCATCTGGTGACGGACAGCCGCGCCGAGCGCTTCGCGGGCAGGTTCCCGGCAGACGAAA
TACATGTCGTAGCGTCGGCGACGATCGGGTCGAAGAATCCTGTAAAGCTCGCACGATCGGCGTGGAAGCTCTGGACGGGT
TTGAGAGCAGCCCGGCGGCTGATTTCCAGGCTCAAGCCGATGGCCGTCGTCGGTTTCGGCGGCTATCCGACTGTGCCGCC
GCTGCTCGCGGCAACCGGCATGGGCGTCCCGACGATCATCCACGAACAGAATGCGGTCATGGGGCGCGCCAATAAGATGC
TCGCATCGCGCGTTGCGGCCATTGCCGGCGGCTTTCTTCCGGAGGGTACGGGAGCCTTCGCTGCAAAGACCGTTGCAACG
GGGAATCCTGTGCGACCTGCGGTGCTGGAAGCCGCGAGGGTGCCCTACGCGCCGGCCGGTGGTGACGCGCCTTTTCATCT
CGTGGTGTTCGGGGGCAGCCAGGGGGCGCAATTTTTCTCGAAGGCAGTGCCGCAAGCTGTCTGCCGGCTCGACGACGCTT
TGCGCCGGCGGCTGAAGGTGACGCAGCAGGCGCGTCCCGAGGACAGGGAAGGTGTCATCGCGTCTTACGAGAAGCTCGAC
ATTCCGGCCGAAGTATCCCCTTTCTTCACCGACATGGCGGGGCGGATCGCCTCCGCGCAGCTCGTTATCTGCCGTTCCGG
TGCTTCCACCGTTTCGGAAGTCTCGGTCATCGGCCGGCCGGCAATCCTGGTCCCATATCCCTATGCGCTCGACCACGACC
AGGCGGCAAATGCGGCTGCGCTGGCCGCGAAAGGCGGCGCGCGCGTGATCGCCCAGGTGGAGCTCAGCGCCGAGCGGCTT
GCAAACATTCTAACAGATGCAATGAGCAACCCGGATACCCTGGCGCAGATGGCGGCTGGTGCCCGCCAGACCGGCAAGGC
GGGTGCCGCGCGCTTGCTTGCGTTACTGGTAGAGGCTATTGCCAGCGGCTCGACAGTCGCGAAGTTCAAGGAAACACGTT
CATGA

Upstream 100 bases:

>100_bases
TGGCACTGACGCGCCATAGGCCGGAGAAGCGTGCCGTCGAGCGCAGCCTCTTTCGATCGGGCGTCGGGGTGCCCGCCGAA
TGAGACATGGATAGTGAGAC

Downstream 100 bases:

>100_bases
AGATGCCGAAGACGATCGGGCTCGTACATTTCATTGGTATCGGCGGCATCGGCATGAGCGGTATTGCCGAGGTGCTGCAC
AATCTCGGCCATCGCGTCCA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDKGIILLAAGGTGGHLFPAEALAHELKASGYSVHLVTDSRAERFAGRFPADEIHVVASATIGSKNPVKLARSAWKLWTG
LRAARRLISRLKPMAVVGFGGYPTVPPLLAATGMGVPTIIHEQNAVMGRANKMLASRVAAIAGGFLPEGTGAFAAKTVAT
GNPVRPAVLEAARVPYAPAGGDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRRRLKVTQQARPEDREGVIASYEKLD
IPAEVSPFFTDMAGRIASAQLVICRSGASTVSEVSVIGRPAILVPYPYALDHDQAANAAALAAKGGARVIAQVELSAERL
ANILTDAMSNPDTLAQMAAGARQTGKAGAARLLALLVEAIASGSTVAKFKETRS

Sequences:

>Translated_374_residues
MDKGIILLAAGGTGGHLFPAEALAHELKASGYSVHLVTDSRAERFAGRFPADEIHVVASATIGSKNPVKLARSAWKLWTG
LRAARRLISRLKPMAVVGFGGYPTVPPLLAATGMGVPTIIHEQNAVMGRANKMLASRVAAIAGGFLPEGTGAFAAKTVAT
GNPVRPAVLEAARVPYAPAGGDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRRRLKVTQQARPEDREGVIASYEKLD
IPAEVSPFFTDMAGRIASAQLVICRSGASTVSEVSVIGRPAILVPYPYALDHDQAANAAALAAKGGARVIAQVELSAERL
ANILTDAMSNPDTLAQMAAGARQTGKAGAARLLALLVEAIASGSTVAKFKETRS
>Mature_374_residues
MDKGIILLAAGGTGGHLFPAEALAHELKASGYSVHLVTDSRAERFAGRFPADEIHVVASATIGSKNPVKLARSAWKLWTG
LRAARRLISRLKPMAVVGFGGYPTVPPLLAATGMGVPTIIHEQNAVMGRANKMLASRVAAIAGGFLPEGTGAFAAKTVAT
GNPVRPAVLEAARVPYAPAGGDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRRRLKVTQQARPEDREGVIASYEKLD
IPAEVSPFFTDMAGRIASAQLVICRSGASTVSEVSVIGRPAILVPYPYALDHDQAANAAALAAKGGARVIAQVELSAERL
ANILTDAMSNPDTLAQMAAGARQTGKAGAARLLALLVEAIASGSTVAKFKETRS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=341, Percent_Identity=36.0703812316716, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38828; Mature: 38828

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKGIILLAAGGTGGHLFPAEALAHELKASGYSVHLVTDSRAERFAGRFPADEIHVVASA
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCEEEEEEE
TIGSKNPVKLARSAWKLWTGLRAARRLISRLKPMAVVGFGGYPTVPPLLAATGMGVPTII
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCEEE
HEQNAVMGRANKMLASRVAAIAGGFLPEGTGAFAAKTVATGNPVRPAVLEAARVPYAPAG
ECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHCCCCCCC
GDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRRRLKVTQQARPEDREGVIASYEKLD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
IPAEVSPFFTDMAGRIASAQLVICRSGASTVSEVSVIGRPAILVPYPYALDHDQAANAAA
CCCCCCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCHHH
LAAKGGARVIAQVELSAERLANILTDAMSNPDTLAQMAAGARQTGKAGAARLLALLVEAI
HHCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCHHHHHHHHHHHHHHH
ASGSTVAKFKETRS
HCCCHHHHHHHCCC
>Mature Secondary Structure
MDKGIILLAAGGTGGHLFPAEALAHELKASGYSVHLVTDSRAERFAGRFPADEIHVVASA
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCEEEEEEE
TIGSKNPVKLARSAWKLWTGLRAARRLISRLKPMAVVGFGGYPTVPPLLAATGMGVPTII
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCEEE
HEQNAVMGRANKMLASRVAAIAGGFLPEGTGAFAAKTVATGNPVRPAVLEAARVPYAPAG
ECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHCCCCCCC
GDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRRRLKVTQQARPEDREGVIASYEKLD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
IPAEVSPFFTDMAGRIASAQLVICRSGASTVSEVSVIGRPAILVPYPYALDHDQAANAAA
CCCCCCHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCHHH
LAAKGGARVIAQVELSAERLANILTDAMSNPDTLAQMAAGARQTGKAGAARLLALLVEAI
HHCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHCCHHHHHHHHHHHHHHH
ASGSTVAKFKETRS
HCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]