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The map label for this gene is panC [H]

Identifier: 150397261

GI number: 150397261

Start: 2111017

End: 2111892

Strand: Reverse

Name: panC [H]

Synonym: Smed_2060

Alternate gene names: 150397261

Gene position: 2111892-2111017 (Counterclockwise)

Preceding gene: 150397269

Following gene: 150397260

Centisome position: 55.84

GC content: 62.44

Gene sequence:

>876_bases
ATGAGAACTATCACCACCATTGCAGAACTGCGTGACGCCCTTGCCGAACACCGGCGGGCGGGCAGGTCCGTCGGTCTGGT
CCCCACGATGGGTTATCTTCATGTCGGACACATGGAGCTCGTTCGCCGCGCCCGCGGCGAGAATGACGTGGTGGTGGCGA
GCATTTTCGTCAATCCGCTTCAGTTCGGCGCAAACGAGGATCTCGGCGAATATCCGCGTGACCTTGCCCGCGATCAGGAG
CTGCTGACGGATGGCGGGGTCGACATCCTGTTTGCCCCCGGCGTTTCCGACATGTATCCGAGGCCGATGGAAACGGTGGT
CGACGTGCCGAAGCTTGGCTCCGAACTCGAAGGCGCAGTCAGGCCCGGCCATTTCGCAGGCGTTGCCACTGTCGTGACAA
AGCTCTTCAACATCGTCCAGCCGGACCGCGCCTATTTCGGTGAGAAGGATTTCCAGCAACTCCAGATCATACGCCGCATG
GTCGAGGATCTGGCGCAGCCGGTCAAGGTGGTCGGCGTACCGACGGTGCGCGAGGAGGACGGGCTCGCCTGTTCGTCGCG
CAACGTATATCTGACGACGGAAGAACGTCGCGCAGCCGCGATCGTGCCGAGGGCACTGGACGAGGCCGAGCGGCTGATCG
CAAGCGGCGTCACCGAGCCGGCCGAGATCGAGAAGCGTGTCCTGGAATTTCTCGCCGGTGAGCCGCTGGCGCGGCCTGAA
GTGGTGGCGCTGCGCGACCCGGAAACGCTTGAACCCTTCGGCGAAATCTCAGGAAAGCCGGTCCTCATTTTGCTTTTCGT
CCGCTTCGGCACGACGAAGCTGCTCGACAACCGCGTCATAGCCCCGAAATCCGCCCGTTTTGCAAAGGTAGCGTGA

Upstream 100 bases:

>100_bases
GATTTTGCCCTTAGATCGGTAAGGAGTTAAGGAATCATGCAGGAGCCATATCAGCGTGGCGTGCCGTTTTTCTCGCCCCG
GCGGATTGGAGGATCCGGAA

Downstream 100 bases:

>100_bases
GAATGAGCGTCCACACCACGAAACGGCGGCTCAGCCCCGCCAGCATCGAATCCCTGAAAGGCGACCGACCGATCGTAAGC
CTGACGGCCTATACGACGCC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRTITTIAELRDALAEHRRAGRSVGLVPTMGYLHVGHMELVRRARGENDVVVASIFVNPLQFGANEDLGEYPRDLARDQE
LLTDGGVDILFAPGVSDMYPRPMETVVDVPKLGSELEGAVRPGHFAGVATVVTKLFNIVQPDRAYFGEKDFQQLQIIRRM
VEDLAQPVKVVGVPTVREEDGLACSSRNVYLTTEERRAAAIVPRALDEAERLIASGVTEPAEIEKRVLEFLAGEPLARPE
VVALRDPETLEPFGEISGKPVLILLFVRFGTTKLLDNRVIAPKSARFAKVA

Sequences:

>Translated_291_residues
MRTITTIAELRDALAEHRRAGRSVGLVPTMGYLHVGHMELVRRARGENDVVVASIFVNPLQFGANEDLGEYPRDLARDQE
LLTDGGVDILFAPGVSDMYPRPMETVVDVPKLGSELEGAVRPGHFAGVATVVTKLFNIVQPDRAYFGEKDFQQLQIIRRM
VEDLAQPVKVVGVPTVREEDGLACSSRNVYLTTEERRAAAIVPRALDEAERLIASGVTEPAEIEKRVLEFLAGEPLARPE
VVALRDPETLEPFGEISGKPVLILLFVRFGTTKLLDNRVIAPKSARFAKVA
>Mature_291_residues
MRTITTIAELRDALAEHRRAGRSVGLVPTMGYLHVGHMELVRRARGENDVVVASIFVNPLQFGANEDLGEYPRDLARDQE
LLTDGGVDILFAPGVSDMYPRPMETVVDVPKLGSELEGAVRPGHFAGVATVVTKLFNIVQPDRAYFGEKDFQQLQIIRRM
VEDLAQPVKVVGVPTVREEDGLACSSRNVYLTTEERRAAAIVPRALDEAERLIASGVTEPAEIEKRVLEFLAGEPLARPE
VVALRDPETLEPFGEISGKPVLILLFVRFGTTKLLDNRVIAPKSARFAKVA

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=286, Percent_Identity=47.2027972027972, Blast_Score=237, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6322046, Length=306, Percent_Identity=37.9084967320261, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32017; Mature: 32017

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTITTIAELRDALAEHRRAGRSVGLVPTMGYLHVGHMELVRRARGENDVVVASIFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
QFGANEDLGEYPRDLARDQELLTDGGVDILFAPGVSDMYPRPMETVVDVPKLGSELEGAV
HCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHCHHHCCHHHHCCC
RPGHFAGVATVVTKLFNIVQPDRAYFGEKDFQQLQIIRRMVEDLAQPVKVVGVPTVREED
CCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
GLACSSRNVYLTTEERRAAAIVPRALDEAERLIASGVTEPAEIEKRVLEFLAGEPLARPE
CCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
VVALRDPETLEPFGEISGKPVLILLFVRFGTTKLLDNRVIAPKSARFAKVA
EEEECCCCHHCHHHHCCCCCEEEEEEEHHCCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTITTIAELRDALAEHRRAGRSVGLVPTMGYLHVGHMELVRRARGENDVVVASIFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
QFGANEDLGEYPRDLARDQELLTDGGVDILFAPGVSDMYPRPMETVVDVPKLGSELEGAV
HCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHCHHHCCHHHHCCC
RPGHFAGVATVVTKLFNIVQPDRAYFGEKDFQQLQIIRRMVEDLAQPVKVVGVPTVREED
CCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
GLACSSRNVYLTTEERRAAAIVPRALDEAERLIASGVTEPAEIEKRVLEFLAGEPLARPE
CCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
VVALRDPETLEPFGEISGKPVLILLFVRFGTTKLLDNRVIAPKSARFAKVA
EEEECCCCHHCHHHHCCCCCEEEEEEEHHCCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]