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The map label for this gene is prmA [H]

Identifier: 150397255

GI number: 150397255

Start: 2105039

End: 2105932

Strand: Direct

Name: prmA [H]

Synonym: Smed_2054

Alternate gene names: 150397255

Gene position: 2105039-2105932 (Clockwise)

Preceding gene: 150397254

Following gene: 150397256

Centisome position: 55.66

GC content: 61.52

Gene sequence:

>894_bases
ATGCCGAAGGAAAGCACCGTGAGCGAGATACGCCTTTTCGTCACCACCACCGAGAAGCAGGCGACAGCCGTACTCGACGT
CATGAGCGCGATCTTCGAAGACGACGATTACGCGATAGCTACCATGGAGATCGACGAGAAGCGTGATGTCTGGGAAGCTT
CGGTCTATATGATGGCCGACGAAGAAGAGAGCGTGAGATCGCGCCTCGCTCAGGCACTCGAAGCCGATTTTGCGAATCTT
CCGATCGAGCGCGAAGTGCTGCCGGATGTGGACTGGATTGCCAAATCGCTCGAGGGCCTCGCCCCTGTGCGCGCAGGTCG
CTTCGTCATCCACGGTTCGCACGACCGTGACAGGGTTAAACCCGGCGAGATCGCCATCGAGATCGATGCCGGGCAGGCCT
TCGGCACCGGCCATCACGGCACCACGGCCGGCTGCCTTGAAATGCTTGCCTCTGTCGCCCGGTCTCGGCCTGTCAGCAAC
GCTCTCGACCTGGGAACGGGAAGCGGTGTGCTGGCGATCGCCGCCTGGAAGCTTCTTCACGTGCCGGTGCTTGCAACCGA
CATCGATCCTGTCGCGACTTTCGTCGCCTCCGAAAACGCCCGTCGAAACGGTGTCGTCACCGGCTTGACCTTCGCCACCG
CGCCCGGCTTTCACTCGAATACCTTCAGCGCCAGCGGCCCCTTCGACCTCATCATCGCCAACATCCTGGCGCGGCCGCTG
ATGAAGATGGCACCGCAACTTGCCGCAAATCTCGCCCCCGGAGGCTCGGTCATTCTCTCCGGCATCCTCGCCGAGCAGCG
CTGGAAGGTGATCGCGGCCTATAATGGCCAGAACCTCAAGCATGCGCGCACCATTTGGCGCAACGGCTGGGTAACCATCC
ATCTGACCCGATAA

Upstream 100 bases:

>100_bases
CGCTTTGCGTTTGTCCTCCATTCATGATAGCGGCGAAACCGACCACAGCGCAGGCATCCGATCGGACGTGCTGAAGACGC
TATGGCCCTTGAATGGCTGT

Downstream 100 bases:

>100_bases
GAGACTCTGCTTCGGTCCTTATTCCTCGACATCGGGATGAGGACCGTAAGAGTTCCAGCTGAGAAGAGAGCCTGAAACCG
AAAAGGCCGCCCAGTCCATC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPKESTVSEIRLFVTTTEKQATAVLDVMSAIFEDDDYAIATMEIDEKRDVWEASVYMMADEEESVRSRLAQALEADFANL
PIEREVLPDVDWIAKSLEGLAPVRAGRFVIHGSHDRDRVKPGEIAIEIDAGQAFGTGHHGTTAGCLEMLASVARSRPVSN
ALDLGTGSGVLAIAAWKLLHVPVLATDIDPVATFVASENARRNGVVTGLTFATAPGFHSNTFSASGPFDLIIANILARPL
MKMAPQLAANLAPGGSVILSGILAEQRWKVIAAYNGQNLKHARTIWRNGWVTIHLTR

Sequences:

>Translated_297_residues
MPKESTVSEIRLFVTTTEKQATAVLDVMSAIFEDDDYAIATMEIDEKRDVWEASVYMMADEEESVRSRLAQALEADFANL
PIEREVLPDVDWIAKSLEGLAPVRAGRFVIHGSHDRDRVKPGEIAIEIDAGQAFGTGHHGTTAGCLEMLASVARSRPVSN
ALDLGTGSGVLAIAAWKLLHVPVLATDIDPVATFVASENARRNGVVTGLTFATAPGFHSNTFSASGPFDLIIANILARPL
MKMAPQLAANLAPGGSVILSGILAEQRWKVIAAYNGQNLKHARTIWRNGWVTIHLTR
>Mature_296_residues
PKESTVSEIRLFVTTTEKQATAVLDVMSAIFEDDDYAIATMEIDEKRDVWEASVYMMADEEESVRSRLAQALEADFANLP
IEREVLPDVDWIAKSLEGLAPVRAGRFVIHGSHDRDRVKPGEIAIEIDAGQAFGTGHHGTTAGCLEMLASVARSRPVSNA
LDLGTGSGVLAIAAWKLLHVPVLATDIDPVATFVASENARRNGVVTGLTFATAPGFHSNTFSASGPFDLIIANILARPLM
KMAPQLAANLAPGGSVILSGILAEQRWKVIAAYNGQNLKHARTIWRNGWVTIHLTR

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=164, Percent_Identity=36.5853658536585, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32079; Mature: 31948

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKESTVSEIRLFVTTTEKQATAVLDVMSAIFEDDDYAIATMEIDEKRDVWEASVYMMAD
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEC
EEESVRSRLAQALEADFANLPIEREVLPDVDWIAKSLEGLAPVRAGRFVIHGSHDRDRVK
CHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
PGEIAIEIDAGQAFGTGHHGTTAGCLEMLASVARSRPVSNALDLGTGSGVLAIAAWKLLH
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHH
VPVLATDIDPVATFVASENARRNGVVTGLTFATAPGFHSNTFSASGPFDLIIANILARPL
CCCEEECCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
MKMAPQLAANLAPGGSVILSGILAEQRWKVIAAYNGQNLKHARTIWRNGWVTIHLTR
HHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEC
>Mature Secondary Structure 
PKESTVSEIRLFVTTTEKQATAVLDVMSAIFEDDDYAIATMEIDEKRDVWEASVYMMAD
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEEEC
EEESVRSRLAQALEADFANLPIEREVLPDVDWIAKSLEGLAPVRAGRFVIHGSHDRDRVK
CHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
PGEIAIEIDAGQAFGTGHHGTTAGCLEMLASVARSRPVSNALDLGTGSGVLAIAAWKLLH
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHH
VPVLATDIDPVATFVASENARRNGVVTGLTFATAPGFHSNTFSASGPFDLIIANILARPL
CCCEEECCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
MKMAPQLAANLAPGGSVILSGILAEQRWKVIAAYNGQNLKHARTIWRNGWVTIHLTR
HHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]