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The map label for this gene is degU [H]

Identifier: 150397182

GI number: 150397182

Start: 2030877

End: 2031557

Strand: Reverse

Name: degU [H]

Synonym: Smed_1980

Alternate gene names: 150397182

Gene position: 2031557-2030877 (Counterclockwise)

Preceding gene: 150397183

Following gene: 150397180

Centisome position: 53.72

GC content: 61.09

Gene sequence:

>681_bases
ATGGACAGGGAAGATCAAACGCATTCCGGCTCATCCATCAGTCCTCGTATCGTGGTGATCGCCGATCACCAGACGGATCT
GGACGAACTGTCGCGCATAATCGGCGCCGAGCCCGAATGGCACTTGATTGCAGCCTGCCGAACCGCCGCGGATGCGATCG
ATACCCTATCCGCCAATCCAGTCGATCTCGTTCTCGTCGACCTAGACCTGACGGAGATGGATGACCTGGAGCTCGTTCGA
CGCTTCAGCCGGGAAATGCCCGGTCTATCCTGCGTCATCCTTGCCGCCGAGATGAACGACGAAGAGCTTGCCGAAGCGAT
GCGGAACGGCGTGGGCGGCGTCGTCCTGAAGGCGCGGGCACAGAGCTCTCTTGTCGACTGCATTCGGGCCGTCGTGGCGG
GACGCACCTATCTTGCCGGCCAAAGCATGAATTCGGTGGTAAGCCGCATTCGGGAACGGGATGCCGAACGCCGCGCGGTC
TTGCAAAAGTTGACACCGCGCGAGTTGGAGATCTCGCGTCTGGCGGCCTCGGGTCTGCGCAGCCGCGAAATCGCCGCGAG
GCTCGGAATAGCCCCGGGGACCGTGAAACTCCATCTCCACAGCGTGTACGGCAAGCTCAATTTAACCACCCGTGTGGAGC
TCGCCAATCTTGCTCAACGACTGCAGCTAGGACACGGCTGA

Upstream 100 bases:

>100_bases
AAGAATGGTGCAGCTTCGATTGTGGCGGCTTCAGCCAGTTGGACCCGCGCCGCACAAGTGGCACCATGGGACGGGTGCTC
CCGATCTATGGGATGGGGCA

Downstream 100 bases:

>100_bases
CGGCGGCAGTGTTGCCGGGCCGGCGCTCGGCCGGCATCCGGACGGAAAAGCCTCTATTCGTTCTCCACGACTTGCCCCGG
GAGCTGCCGGGAGCCCGGTG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDREDQTHSGSSISPRIVVIADHQTDLDELSRIIGAEPEWHLIAACRTAADAIDTLSANPVDLVLVDLDLTEMDDLELVR
RFSREMPGLSCVILAAEMNDEELAEAMRNGVGGVVLKARAQSSLVDCIRAVVAGRTYLAGQSMNSVVSRIRERDAERRAV
LQKLTPRELEISRLAASGLRSREIAARLGIAPGTVKLHLHSVYGKLNLTTRVELANLAQRLQLGHG

Sequences:

>Translated_226_residues
MDREDQTHSGSSISPRIVVIADHQTDLDELSRIIGAEPEWHLIAACRTAADAIDTLSANPVDLVLVDLDLTEMDDLELVR
RFSREMPGLSCVILAAEMNDEELAEAMRNGVGGVVLKARAQSSLVDCIRAVVAGRTYLAGQSMNSVVSRIRERDAERRAV
LQKLTPRELEISRLAASGLRSREIAARLGIAPGTVKLHLHSVYGKLNLTTRVELANLAQRLQLGHG
>Mature_226_residues
MDREDQTHSGSSISPRIVVIADHQTDLDELSRIIGAEPEWHLIAACRTAADAIDTLSANPVDLVLVDLDLTEMDDLELVR
RFSREMPGLSCVILAAEMNDEELAEAMRNGVGGVVLKARAQSSLVDCIRAVVAGRTYLAGQSMNSVVSRIRERDAERRAV
LQKLTPRELEISRLAASGLRSREIAARLGIAPGTVKLHLHSVYGKLNLTTRVELANLAQRLQLGHG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=172, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=26.3414634146341, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=24.1206030150754, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=25.8883248730964, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24676; Mature: 24676

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREDQTHSGSSISPRIVVIADHQTDLDELSRIIGAEPEWHLIAACRTAADAIDTLSANP
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
VDLVLVDLDLTEMDDLELVRRFSREMPGLSCVILAAEMNDEELAEAMRNGVGGVVLKARA
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHH
QSSLVDCIRAVVAGRTYLAGQSMNSVVSRIRERDAERRAVLQKLTPRELEISRLAASGLR
HHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCH
SREIAARLGIAPGTVKLHLHSVYGKLNLTTRVELANLAQRLQLGHG
HHHHHHHHCCCCCEEEEEEEEHHCEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDREDQTHSGSSISPRIVVIADHQTDLDELSRIIGAEPEWHLIAACRTAADAIDTLSANP
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
VDLVLVDLDLTEMDDLELVRRFSREMPGLSCVILAAEMNDEELAEAMRNGVGGVVLKARA
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHH
QSSLVDCIRAVVAGRTYLAGQSMNSVVSRIRERDAERRAVLQKLTPRELEISRLAASGLR
HHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCH
SREIAARLGIAPGTVKLHLHSVYGKLNLTTRVELANLAQRLQLGHG
HHHHHHHHCCCCCEEEEEEEEHHCEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]