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The map label for this gene is cobU [H]

Identifier: 150396964

GI number: 150396964

Start: 1843207

End: 1843734

Strand: Reverse

Name: cobU [H]

Synonym: Smed_1761

Alternate gene names: 150396964

Gene position: 1843734-1843207 (Counterclockwise)

Preceding gene: 150396966

Following gene: 150396963

Centisome position: 48.75

GC content: 62.12

Gene sequence:

>528_bases
ATGGCCACTTCCTCCGTCGGCCCCACCCTCGTGTTGGGCGGCGCTCGCTCCGGCAAATCCAGTTTCGCAGAAAAGCGCGT
CGAGACCTTCGGGTTGCCGATGCATTACCTTGCGACGGGCCGGGCTTTTGACCAGGAGATGCGGGAACGCATCGTCCTTC
ATCAGGCTGCACGGCAGGGCAAGGGCTGGACCACCCATGAGGAACCGCTCGAGCTCGTGGGACTGCTTCGCCGAATCAAT
GATCCCGGGCGTGCTGTCCTCATCGACTGCCTGACCCTGTGGGTGACCAACCTGATGATGGAGGAGCGCGACATGGACGC
TGAATTCGCAGCGCTCGCCGCCTTCCTGCCCGAGGCACGCTCGCGCCTCGTGTTCGTTTCAAATGAGGTCGGTCTCGGAA
TTGTCCCGGACAATCGGATGGCGCGCGACTTTCGCGATCACTCCGGCCGGCTCCACCAGATCGTGGCGGAGAAATCCGCA
GAAGTTTACTTTGTCGCGGCCGGACTGCCGCTGAAAATGAAGGGTTGA

Upstream 100 bases:

>100_bases
GCCAGCACGGAGGTTGTCGTGGCTCATAGATTTCTGATCGAACGCGCTTATTGCGCGCGCTTTTGCTTTTGCCTCCGTAC
CCAGAGTTGAGGCGAGCAGC

Downstream 100 bases:

>100_bases
TCCATGACACTCGCGAAGTCTCAGCAGGGCAAGATTCCCGCTACCGTCATCACCGGGTTTCTCGGTGCCGGCAAGACGAC
GATGATCCGCAATCTGCTGC

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MATSSVGPTLVLGGARSGKSSFAEKRVETFGLPMHYLATGRAFDQEMRERIVLHQAARQGKGWTTHEEPLELVGLLRRIN
DPGRAVLIDCLTLWVTNLMMEERDMDAEFAALAAFLPEARSRLVFVSNEVGLGIVPDNRMARDFRDHSGRLHQIVAEKSA
EVYFVAAGLPLKMKG

Sequences:

>Translated_175_residues
MATSSVGPTLVLGGARSGKSSFAEKRVETFGLPMHYLATGRAFDQEMRERIVLHQAARQGKGWTTHEEPLELVGLLRRIN
DPGRAVLIDCLTLWVTNLMMEERDMDAEFAALAAFLPEARSRLVFVSNEVGLGIVPDNRMARDFRDHSGRLHQIVAEKSA
EVYFVAAGLPLKMKG
>Mature_174_residues
ATSSVGPTLVLGGARSGKSSFAEKRVETFGLPMHYLATGRAFDQEMRERIVLHQAARQGKGWTTHEEPLELVGLLRRIND
PGRAVLIDCLTLWVTNLMMEERDMDAEFAALAAFLPEARSRLVFVSNEVGLGIVPDNRMARDFRDHSGRLHQIVAEKSAE
VYFVAAGLPLKMKG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=37.9120879120879, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19394; Mature: 19262

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSSVGPTLVLGGARSGKSSFAEKRVETFGLPMHYLATGRAFDQEMRERIVLHQAARQG
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
KGWTTHEEPLELVGLLRRINDPGRAVLIDCLTLWVTNLMMEERDMDAEFAALAAFLPEAR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SRLVFVSNEVGLGIVPDNRMARDFRDHSGRLHQIVAEKSAEVYFVAAGLPLKMKG
CCEEEEECCCCEEECCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
ATSSVGPTLVLGGARSGKSSFAEKRVETFGLPMHYLATGRAFDQEMRERIVLHQAARQG
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
KGWTTHEEPLELVGLLRRINDPGRAVLIDCLTLWVTNLMMEERDMDAEFAALAAFLPEAR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SRLVFVSNEVGLGIVPDNRMARDFRDHSGRLHQIVAEKSAEVYFVAAGLPLKMKG
CCEEEEECCCCEEECCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]