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The map label for this gene is csxA [H]

Identifier: 150396927

GI number: 150396927

Start: 1803252

End: 1805726

Strand: Reverse

Name: csxA [H]

Synonym: Smed_1724

Alternate gene names: 150396927

Gene position: 1805726-1803252 (Counterclockwise)

Preceding gene: 150396928

Following gene: 150396926

Centisome position: 47.75

GC content: 61.9

Gene sequence:

>2475_bases
ATGTCTTCCGACACCCCGAACCGCGATGCACTCCGTATCGATCTTTCCGGCGATTGGCTGCTCGCCTCCGCCGACAACAG
CCATGCGCTGACGATCGCGCTGCCGGGCGACGTGCATAGCGCGCTGCAGCGAGCCGGCATCATCGCCGATCCATACCATG
GCCGCAACGAGGCCGAGATCCAATGGGTCGCCCGGAAAGAGTGGGTGCTCGAGCGGACCGTCGTCATCGGTGCGGACGAT
CTGAACGGGGGATGGTATCTCGACTTCGAGAGCATCGATACCGTCGCTTCGGTCTTCGTCAACGAACAGCTTGTGCTGAC
GGCGGAGAACTGCTTTCGCCGTTACCGCCCCGATGTCTCGGATGCGATTGTCGCGGGCGAAAACCGTATTCGCATCATAC
TCCATTCGGCAATTGCCGAGGGTGAACGGCGGCAGGCGGCGCAACCTTTCTACGTGCCCTATCACGACGGCAATTCGCCG
ATTGCCAACGGGAATATGCTGCGCAAGCCGCAATGTCACTTTGGCTGGGACTGGAACATCGCGATCGCGCCGCTCGGTGT
CTACGGCTCTCTCGCGCTTTGCCGGTTGGAGACGGCGCGCATCGAGCATCTCACGACGCGTCAGCTCTGGCTGGAGGACG
GCTCGGTCGATCTGCAGGTGACGGTCCAGCTTTTTGCCCGGGATCCCGGAATAGTGCCGGTCTATTTCACGCTCGACGGA
GTGCGCGAGCGATTGGATTGCGCGGTCGGCCCCGGGGAAACGCGCGTTACCCATGTCTTCACGATAGAGGAGCCGAGGCG
CTGGTGGCCGGCGGGCAGCGGTGACCAAGCGTTTTCGACGCTTAAGGTGGAGGTGCCGGGCGAGACCGTTACGCGTCAAA
TCGGCTTCCGCACCATAAAACTCGTCACCGACAGTGACGAGGCAGGAAGCCGTTTTGCTTTCAGAGTCAACGGCCGAGAG
GTATTCTGCCGCGGTGCAAACTGGATACCGGCGGATGCGCTGAGGTCGCGCGTCACCCCGGAGGCGGTGGAAGACCTCCT
CCGCTCGGCAGTCGACGCGAACATGAACATGATCCGCGTCTGGGGCGGTGGCTTCTACGAGCCCGACTGGTTCTATGATC
TCTGCGACCGGCTCGGTCTGCTCGTCTGGCAGGATTTCATGTTTGCCTGCAATCTGTACCCGTCGACGCCGGATTTTCTC
GAGAATGTTGCGGACGAAGTGGATTATCAGGTCAGGCGGCTTTCGACCCATCCGTCCATAGCGCTCTGGTGCGGCGACAA
CGAACTGGTCGGTGCGCTCACCTGGTTCGAGGAGAGCCGAAAGGACCGGGATCGCTATCTCGTCTCCTACGACCGCCTGA
ACCGGACGGTCGAGACCGCCATGAGGCGGGCCTGCCCGGAAGCGATCTGGTGGCCGTCGAGCCCTTCCGCCGGTTACCTC
GATTTCGGAGACGCCTGGCACGCCGACGGCGCCGGCGACATGCACTACTGGTCCGTCTGGCACGAGAACAAGTCCTTTGA
CAATTACCGCACGGTCCGGCCACGCTTCTGCTCCGAATTCGGCTTTCAATCCTACACGTCGATGCCGGTGATCCGGCAAT
TCGCCGGGGAACGGGACCTCAATATCGCTTCGCCGGTCATGGAGGCACATCAGAAGAATGCCGGCGGCAATGAGCGGATC
GCCGGTACGATGTTCCGCTATTTCCGTTTCCCAAAGGATTTTCCGAGCTTCGTCTATCTGAGCCAGATCCAGCAGGGGCT
CGCGATCCGGACCGCAGTCGATTACTGGCGGTCGCTGAAGCCCCATTGCATGGGCACGCTTTACTGGCAGCTCAACGACA
CCTGGCCGGTCACCTCCTGGTCGAGCCTGGACTTTGGCGGACAGTGGAAGGCAATGCACTATATGGCGCGCCGCTTCTTC
CAGCCGGTTGCCGTAGCAGCGATTCCGTCCGCGGAAGGCAGTGAGGTCGCCATATCGATGGTAAACGACACGGCCGAGCC
GGTCACGGTGGAGCTTCAGGCGTTCCTCGTTTCGCTCGACGGCGAACGGCAACCGCTGCTCGCCGTCGCGGGGACCTGCT
CGCCCGATCGTGCTGCGACGCTCGTGGCCATTGCCGCAAAGGACATCCCGTCCGACATGCTTCTCTTCTGGTCTTTCGAA
GCTTCGAACGGATCGACCAGCGAGGGGCATTATGTCAACGGCACCTATAAAGCGCTCGATCTCGCGCCCTCCGGTCTGAC
AGTCGAGGCAGTACCTCGGCCGGATGGTTCCTTCGATGTCTCGGTGAAGGCGGCCGGGCTTGCCCTGCACGTCATGATAG
AGGCCGATATCGAGGGGCGCTATTCGGATAATGCTTTCGACCTGACCGCCGGCGAGACGAAATCGATCCGTTTCAGGCCG
AGGGTGCCGGTCGATGCCGGCGCGAGCCCGCGCTTCAGCGCCTACGATCTCGAAACCTGCCAGGGAAAAGGGTGA

Upstream 100 bases:

>100_bases
CCGCCTCTGACGAGCCGCAAAGCGGAGCCGGGGCAGCATGCCCCGGTCCGCGTGATCGAAACGGCGGCGGTACAGGCCGC
CGCACGAATGGACTGTGGAA

Downstream 100 bases:

>100_bases
AGGCACACTCCCACTCCCAGGCGACCGTTCCAACCACCAGGAGAGTTCGATGAAAGATGTCAGCTTCCAGCTTTACAGCG
CCCGAAATTTCCCGCCCTTT

Product: beta-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 824; Mature: 823

Protein sequence:

>824_residues
MSSDTPNRDALRIDLSGDWLLASADNSHALTIALPGDVHSALQRAGIIADPYHGRNEAEIQWVARKEWVLERTVVIGADD
LNGGWYLDFESIDTVASVFVNEQLVLTAENCFRRYRPDVSDAIVAGENRIRIILHSAIAEGERRQAAQPFYVPYHDGNSP
IANGNMLRKPQCHFGWDWNIAIAPLGVYGSLALCRLETARIEHLTTRQLWLEDGSVDLQVTVQLFARDPGIVPVYFTLDG
VRERLDCAVGPGETRVTHVFTIEEPRRWWPAGSGDQAFSTLKVEVPGETVTRQIGFRTIKLVTDSDEAGSRFAFRVNGRE
VFCRGANWIPADALRSRVTPEAVEDLLRSAVDANMNMIRVWGGGFYEPDWFYDLCDRLGLLVWQDFMFACNLYPSTPDFL
ENVADEVDYQVRRLSTHPSIALWCGDNELVGALTWFEESRKDRDRYLVSYDRLNRTVETAMRRACPEAIWWPSSPSAGYL
DFGDAWHADGAGDMHYWSVWHENKSFDNYRTVRPRFCSEFGFQSYTSMPVIRQFAGERDLNIASPVMEAHQKNAGGNERI
AGTMFRYFRFPKDFPSFVYLSQIQQGLAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVTSWSSLDFGGQWKAMHYMARRFF
QPVAVAAIPSAEGSEVAISMVNDTAEPVTVELQAFLVSLDGERQPLLAVAGTCSPDRAATLVAIAAKDIPSDMLLFWSFE
ASNGSTSEGHYVNGTYKALDLAPSGLTVEAVPRPDGSFDVSVKAAGLALHVMIEADIEGRYSDNAFDLTAGETKSIRFRP
RVPVDAGASPRFSAYDLETCQGKG

Sequences:

>Translated_824_residues
MSSDTPNRDALRIDLSGDWLLASADNSHALTIALPGDVHSALQRAGIIADPYHGRNEAEIQWVARKEWVLERTVVIGADD
LNGGWYLDFESIDTVASVFVNEQLVLTAENCFRRYRPDVSDAIVAGENRIRIILHSAIAEGERRQAAQPFYVPYHDGNSP
IANGNMLRKPQCHFGWDWNIAIAPLGVYGSLALCRLETARIEHLTTRQLWLEDGSVDLQVTVQLFARDPGIVPVYFTLDG
VRERLDCAVGPGETRVTHVFTIEEPRRWWPAGSGDQAFSTLKVEVPGETVTRQIGFRTIKLVTDSDEAGSRFAFRVNGRE
VFCRGANWIPADALRSRVTPEAVEDLLRSAVDANMNMIRVWGGGFYEPDWFYDLCDRLGLLVWQDFMFACNLYPSTPDFL
ENVADEVDYQVRRLSTHPSIALWCGDNELVGALTWFEESRKDRDRYLVSYDRLNRTVETAMRRACPEAIWWPSSPSAGYL
DFGDAWHADGAGDMHYWSVWHENKSFDNYRTVRPRFCSEFGFQSYTSMPVIRQFAGERDLNIASPVMEAHQKNAGGNERI
AGTMFRYFRFPKDFPSFVYLSQIQQGLAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVTSWSSLDFGGQWKAMHYMARRFF
QPVAVAAIPSAEGSEVAISMVNDTAEPVTVELQAFLVSLDGERQPLLAVAGTCSPDRAATLVAIAAKDIPSDMLLFWSFE
ASNGSTSEGHYVNGTYKALDLAPSGLTVEAVPRPDGSFDVSVKAAGLALHVMIEADIEGRYSDNAFDLTAGETKSIRFRP
RVPVDAGASPRFSAYDLETCQGKG
>Mature_823_residues
SSDTPNRDALRIDLSGDWLLASADNSHALTIALPGDVHSALQRAGIIADPYHGRNEAEIQWVARKEWVLERTVVIGADDL
NGGWYLDFESIDTVASVFVNEQLVLTAENCFRRYRPDVSDAIVAGENRIRIILHSAIAEGERRQAAQPFYVPYHDGNSPI
ANGNMLRKPQCHFGWDWNIAIAPLGVYGSLALCRLETARIEHLTTRQLWLEDGSVDLQVTVQLFARDPGIVPVYFTLDGV
RERLDCAVGPGETRVTHVFTIEEPRRWWPAGSGDQAFSTLKVEVPGETVTRQIGFRTIKLVTDSDEAGSRFAFRVNGREV
FCRGANWIPADALRSRVTPEAVEDLLRSAVDANMNMIRVWGGGFYEPDWFYDLCDRLGLLVWQDFMFACNLYPSTPDFLE
NVADEVDYQVRRLSTHPSIALWCGDNELVGALTWFEESRKDRDRYLVSYDRLNRTVETAMRRACPEAIWWPSSPSAGYLD
FGDAWHADGAGDMHYWSVWHENKSFDNYRTVRPRFCSEFGFQSYTSMPVIRQFAGERDLNIASPVMEAHQKNAGGNERIA
GTMFRYFRFPKDFPSFVYLSQIQQGLAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVTSWSSLDFGGQWKAMHYMARRFFQ
PVAVAAIPSAEGSEVAISMVNDTAEPVTVELQAFLVSLDGERQPLLAVAGTCSPDRAATLVAIAAKDIPSDMLLFWSFEA
SNGSTSEGHYVNGTYKALDLAPSGLTVEAVPRPDGSFDVSVKAAGLALHVMIEADIEGRYSDNAFDLTAGETKSIRFRPR
VPVDAGASPRFSAYDLETCQGKG

Specific function: Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has no beta-mannosidase activity [H]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Secreted, extracellular space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI84798622, Length=864, Percent_Identity=29.3981481481481, Blast_Score=371, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550784, Length=880, Percent_Identity=28.4090909090909, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24643838, Length=730, Percent_Identity=33.013698630137, Blast_Score=301, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24643840, Length=627, Percent_Identity=33.652312599681, Blast_Score=275, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.165 [H]

Molecular weight: Translated: 92276; Mature: 92145

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDTPNRDALRIDLSGDWLLASADNSHALTIALPGDVHSALQRAGIIADPYHGRNEAEI
CCCCCCCCCEEEEEECCCEEEEECCCCCEEEEEECCHHHHHHHHCCCEECCCCCCCCCEE
QWVARKEWVLERTVVIGADDLNGGWYLDFESIDTVASVFVNEQLVLTAENCFRRYRPDVS
EEEEHHHEEEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCHH
DAIVAGENRIRIILHSAIAEGERRQAAQPFYVPYHDGNSPIANGNMLRKPQCHFGWDWNI
HEEEECCCEEEEEEEEHHCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
AIAPLGVYGSLALCRLETARIEHLTTRQLWLEDGSVDLQVTVQLFARDPGIVPVYFTLDG
EEEECCHHCCEEEEEEHHHHHHHHHEEEEEEECCCEEEEEEEEEEECCCCCEEEEEEEHH
VRERLDCAVGPGETRVTHVFTIEEPRRWWPAGSGDQAFSTLKVEVPGETVTRQIGFRTIK
HHHHHHCCCCCCCCEEEEEEEECCCHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCEEEE
LVTDSDEAGSRFAFRVNGREVFCRGANWIPADALRSRVTPEAVEDLLRSAVDANMNMIRV
EEECCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEEE
WGGGFYEPDWFYDLCDRLGLLVWQDFMFACNLYPSTPDFLENVADEVDYQVRRLSTHPSI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHEECCCCCE
ALWCGDNELVGALTWFEESRKDRDRYLVSYDRLNRTVETAMRRACPEAIWWPSSPSAGYL
EEEECCCCEEEEEHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCEE
DFGDAWHADGAGDMHYWSVWHENKSFDNYRTVRPRFCSEFGFQSYTSMPVIRQFAGERDL
ECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCCC
NIASPVMEAHQKNAGGNERIAGTMFRYFRFPKDFPSFVYLSQIQQGLAIRTAVDYWRSLK
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
PHCMGTLYWQLNDTWPVTSWSSLDFGGQWKAMHYMARRFFQPVAVAAIPSAEGSEVAISM
CCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEE
VNDTAEPVTVELQAFLVSLDGERQPLLAVAGTCSPDRAATLVAIAAKDIPSDMLLFWSFE
ECCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHEEEEEEEECCCCCCEEEEEEEE
ASNGSTSEGHYVNGTYKALDLAPSGLTVEAVPRPDGSFDVSVKAAGLALHVMIEADIEGR
CCCCCCCCCEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCEEEEEEEEECCCCC
YSDNAFDLTAGETKSIRFRPRVPVDAGASPRFSAYDLETCQGKG
CCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SSDTPNRDALRIDLSGDWLLASADNSHALTIALPGDVHSALQRAGIIADPYHGRNEAEI
CCCCCCCCEEEEEECCCEEEEECCCCCEEEEEECCHHHHHHHHCCCEECCCCCCCCCEE
QWVARKEWVLERTVVIGADDLNGGWYLDFESIDTVASVFVNEQLVLTAENCFRRYRPDVS
EEEEHHHEEEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCHH
DAIVAGENRIRIILHSAIAEGERRQAAQPFYVPYHDGNSPIANGNMLRKPQCHFGWDWNI
HEEEECCCEEEEEEEEHHCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
AIAPLGVYGSLALCRLETARIEHLTTRQLWLEDGSVDLQVTVQLFARDPGIVPVYFTLDG
EEEECCHHCCEEEEEEHHHHHHHHHEEEEEEECCCEEEEEEEEEEECCCCCEEEEEEEHH
VRERLDCAVGPGETRVTHVFTIEEPRRWWPAGSGDQAFSTLKVEVPGETVTRQIGFRTIK
HHHHHHCCCCCCCCEEEEEEEECCCHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCEEEE
LVTDSDEAGSRFAFRVNGREVFCRGANWIPADALRSRVTPEAVEDLLRSAVDANMNMIRV
EEECCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEEE
WGGGFYEPDWFYDLCDRLGLLVWQDFMFACNLYPSTPDFLENVADEVDYQVRRLSTHPSI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHEECCCCCE
ALWCGDNELVGALTWFEESRKDRDRYLVSYDRLNRTVETAMRRACPEAIWWPSSPSAGYL
EEEECCCCEEEEEHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCEE
DFGDAWHADGAGDMHYWSVWHENKSFDNYRTVRPRFCSEFGFQSYTSMPVIRQFAGERDL
ECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCCC
NIASPVMEAHQKNAGGNERIAGTMFRYFRFPKDFPSFVYLSQIQQGLAIRTAVDYWRSLK
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
PHCMGTLYWQLNDTWPVTSWSSLDFGGQWKAMHYMARRFFQPVAVAAIPSAEGSEVAISM
CCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEE
VNDTAEPVTVELQAFLVSLDGERQPLLAVAGTCSPDRAATLVAIAAKDIPSDMLLFWSFE
ECCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHEEEEEEEECCCCCCEEEEEEEE
ASNGSTSEGHYVNGTYKALDLAPSGLTVEAVPRPDGSFDVSVKAAGLALHVMIEADIEGR
CCCCCCCCCEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCEEEEEEEEECCCCC
YSDNAFDLTAGETKSIRFRPRVPVDAGASPRFSAYDLETCQGKG
CCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]