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The map label for this gene is rpiA [H]

Identifier: 150396782

GI number: 150396782

Start: 1670631

End: 1671326

Strand: Reverse

Name: rpiA [H]

Synonym: Smed_1573

Alternate gene names: 150396782

Gene position: 1671326-1670631 (Counterclockwise)

Preceding gene: 150396784

Following gene: 150396781

Centisome position: 44.19

GC content: 61.35

Gene sequence:

>696_bases
ATGGACGCCCGCCAAATGAAGATCAAGGCTGCCGAAGCGGCGCTTGAACATGTCGAAAACGGTATGCGGCTCGGAATCGG
CACTGGCTCGACTGCAGAAGAGTTTGTCAGGGTCCTGGCGGAGAAGGTGGCCTCCGGCTTTCAGATCTCCGGCGTCCCGA
CGTCCGAGCGGACGGCGCGCCTCTGCCTCGAGCTCGGTGTGCCTCTCAAGTCGCTCGACGAACTGCCGGAACTGGACCTG
ACCATCGACGGAGCCGACGAAGTCGACGGAAAACTGCGCCTGATCAAGGGCGGCGGTGGTGCGTTGCTGAGGGAGAAGAT
TGTCGCGAGCGCTTCGGCGCGGATGATCGTCATCGCCGACGAAACAAAGGTCGTGGACGTCCTTGGCGCCTTCAAGCTGC
CGATAGAGGTCAATCCTTTCGGCCAGCTCGCCACGCGGCTCGCAATCGAGAAGGTTGCTTCGCGTCTGGGTTTGACGGGG
GACATCGTCGTGCGCGCATCGGGCGACGGACCCTTCATGACCGATGGCGGACACCTGATTCTCGATGCATCTTTTGGCCG
TATTCCTGATGCAGATGCGCTCGCGGTAGAGCTGAATGCCATCCCGGGGGTCGTTGAGCACGGGCTTTTCATAGAAATGG
CGTCGATGGCGATCATTGCCGGTCCTGAGGGAGCGCGCACGCTTAAGGCGTCTTGA

Upstream 100 bases:

>100_bases
TTGTTTGCCGCAGCGGGCGTGTAAGTGTCTCAGCGGAATGGGAAGGTGACGGCTGAGGCCGGCGCCCCGCCCGACGTGGT
CGAGAAGGAGCGAATGGCGC

Downstream 100 bases:

>100_bases
GCCGCTCCGGTTGAGCGGCACGGGGCGAATCGAGAGACAGACTTTGCACAGGTCAGCCTGGAGGCGGCTATCGGCCGGGC
GACATGTGCCAACACAGGAG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTARLCLELGVPLKSLDELPELDL
TIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIADETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTG
DIVVRASGDGPFMTDGGHLILDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS

Sequences:

>Translated_231_residues
MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTARLCLELGVPLKSLDELPELDL
TIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIADETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTG
DIVVRASGDGPFMTDGGHLILDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS
>Mature_231_residues
MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTARLCLELGVPLKSLDELPELDL
TIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIADETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTG
DIVVRASGDGPFMTDGGHLILDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=232, Percent_Identity=40.5172413793103, Blast_Score=146, Evalue=1e-35,
Organism=Escherichia coli, GI1789280, Length=230, Percent_Identity=38.695652173913, Blast_Score=138, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=233, Percent_Identity=39.9141630901288, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=37.2727272727273, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364072, Length=210, Percent_Identity=39.0476190476191, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24121; Mature: 24121

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTAR
CCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHH
LCLELGVPLKSLDELPELDLTIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIAD
HHHHHCCCHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEC
ETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTGDIVVRASGDGPFMTDGGHLI
CCEEEEEHHCEECCEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCEEE
LDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS
EECCCCCCCCCCEEEEEECCCCCHHHCCHHEEEEEEEEEECCCCCEEECCC
>Mature Secondary Structure
MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTAR
CCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHH
LCLELGVPLKSLDELPELDLTIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIAD
HHHHHCCCHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEC
ETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTGDIVVRASGDGPFMTDGGHLI
CCEEEEEHHCEECCEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCEEE
LDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS
EECCCCCCCCCCEEEEEECCCCCHHHCCHHEEEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]