Click here to switch to the map view.

The map label for this gene is vanR [H]

Identifier: 150396769

GI number: 150396769

Start: 1653276

End: 1654016

Strand: Direct

Name: vanR [H]

Synonym: Smed_1559

Alternate gene names: 150396769

Gene position: 1653276-1654016 (Clockwise)

Preceding gene: 150396768

Following gene: 150396770

Centisome position: 43.72

GC content: 59.78

Gene sequence:

>741_bases
ATGACTAATCAACAAGCTGTCCTCAATTTGCTGGATATTGTGGAGTATGGAGGTTGCGCAGACCCCGAGCGCTTCTTCGC
CCTGATGCGACGAACCTTCAACATCGCGCACCTCTTATACCTGGAAGCGGAGTCTCTTCCGGATGGTCTGAGAATCTGCC
GTCTGCATCACACGTTTGGCGCCTATGCCGCCGAAGTCTACGCCGTACGAGGCCTCCACAGGATCGATCCGATCCTCAAG
CTTGCGCTTGGCGGTGTCAGACCGGTCGAATGGGCGACGGCACGGCGACGCTTTCCGGAGTGCGAGCCACTTTTCGTGGC
GGCCGAGGAAATAGGACTTTCCACTGAGGGTGTCGCCTTGCCGCTGCCTTCGCCCGCCGGCCGCATGGCCCTCCTCGCGA
TCAGCGCCAACATGTCGCCGGTCGAGTGGTCCGCCTACCGCCGTTGCCATCTGCGGGATTTCCAACTGGCTGCGAACCTG
TTCCATGCATCTATGCTCGAACATTCGGCAATGGCTGGGGCGATGGAAGACGAGCGCGATCTCCGCCTGACCGGGCGGGA
GACCGAGGTCCTGACCTGGTCGGCGGCTGGCAAGAGCTATTGGGAGATTGCGACTATACTCGGCATATCCGAGCGAACCG
TGCGCTTCTTCATGACCAATGCCCGCCGCAAACTGAATGTGGTGTCCAATACTCAAGCTGTAGCCCATGCTGTTCGACAC
GCGCTGATTCCCACCGTCTGA

Upstream 100 bases:

>100_bases
GTAAATAAGCAAATAACACACCGAATACGAAATATAGCACTAGACAAAACCGGCCGCCTTAAACCATGTTTATTATAGGG
GCAAGTTTCGGTGTTACGGC

Downstream 100 bases:

>100_bases
GGGGTTGCCGGTCCGGCACAAGCCCGGCACCAGCAGATTCCCCAAAAATCTATTGGGAAAAAATGTAGAAATAAACTGTC
ACTATAGACAGTTACATGTG

Product: regulatory protein LuxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTNQQAVLNLLDIVEYGGCADPERFFALMRRTFNIAHLLYLEAESLPDGLRICRLHHTFGAYAAEVYAVRGLHRIDPILK
LALGGVRPVEWATARRRFPECEPLFVAAEEIGLSTEGVALPLPSPAGRMALLAISANMSPVEWSAYRRCHLRDFQLAANL
FHASMLEHSAMAGAMEDERDLRLTGRETEVLTWSAAGKSYWEIATILGISERTVRFFMTNARRKLNVVSNTQAVAHAVRH
ALIPTV

Sequences:

>Translated_246_residues
MTNQQAVLNLLDIVEYGGCADPERFFALMRRTFNIAHLLYLEAESLPDGLRICRLHHTFGAYAAEVYAVRGLHRIDPILK
LALGGVRPVEWATARRRFPECEPLFVAAEEIGLSTEGVALPLPSPAGRMALLAISANMSPVEWSAYRRCHLRDFQLAANL
FHASMLEHSAMAGAMEDERDLRLTGRETEVLTWSAAGKSYWEIATILGISERTVRFFMTNARRKLNVVSNTQAVAHAVRH
ALIPTV
>Mature_245_residues
TNQQAVLNLLDIVEYGGCADPERFFALMRRTFNIAHLLYLEAESLPDGLRICRLHHTFGAYAAEVYAVRGLHRIDPILKL
ALGGVRPVEWATARRRFPECEPLFVAAEEIGLSTEGVALPLPSPAGRMALLAISANMSPVEWSAYRRCHLRDFQLAANLF
HASMLEHSAMAGAMEDERDLRLTGRETEVLTWSAAGKSYWEIATILGISERTVRFFMTNARRKLNVVSNTQAVAHAVRHA
LIPTV

Specific function: Probable transcriptional activator. Binds to autoinducer molecule ODHL [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788224, Length=185, Percent_Identity=30.2702702702703, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 27440; Mature: 27309

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQQAVLNLLDIVEYGGCADPERFFALMRRTFNIAHLLYLEAESLPDGLRICRLHHTFG
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHH
AYAAEVYAVRGLHRIDPILKLALGGVRPVEWATARRRFPECEPLFVAAEEIGLSTEGVAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEHHHHCCCCCCEEE
PLPSPAGRMALLAISANMSPVEWSAYRRCHLRDFQLAANLFHASMLEHSAMAGAMEDERD
ECCCCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LRLTGRETEVLTWSAAGKSYWEIATILGISERTVRFFMTNARRKLNVVSNTQAVAHAVRH
EEEECCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
ALIPTV
HHCCCC
>Mature Secondary Structure 
TNQQAVLNLLDIVEYGGCADPERFFALMRRTFNIAHLLYLEAESLPDGLRICRLHHTFG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHH
AYAAEVYAVRGLHRIDPILKLALGGVRPVEWATARRRFPECEPLFVAAEEIGLSTEGVAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEHHHHCCCCCCEEE
PLPSPAGRMALLAISANMSPVEWSAYRRCHLRDFQLAANLFHASMLEHSAMAGAMEDERD
ECCCCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LRLTGRETEVLTWSAAGKSYWEIATILGISERTVRFFMTNARRKLNVVSNTQAVAHAVRH
EEEECCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
ALIPTV
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9139920 [H]