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The map label for this gene is purQ [H]

Identifier: 150396712

GI number: 150396712

Start: 1582340

End: 1583011

Strand: Direct

Name: purQ [H]

Synonym: Smed_1500

Alternate gene names: 150396712

Gene position: 1582340-1583011 (Clockwise)

Preceding gene: 150396711

Following gene: 150396713

Centisome position: 41.84

GC content: 62.65

Gene sequence:

>672_bases
ATGAAATCCGCCGTCGTTCAGCTTCCAGGTCTCAATCGCGACCGCGACATGATCGCTGCCCTGACCAAGATCTCCGGCAG
CGCGCCAGTCACCGTCTGGCAGACCGAGACCGAGATCCCGGACGTTGATCTGATCGTCATCCCCGGCGGCTTTTCCTATG
GCGATTATCTGCGCTGCGGCGCGATCGCGGCACGCATGCCCGTGATGCAGGCGATCAAGGCCCGGGCGGAACAAGGTGTC
CGCGTCCTCGGCGTCTGCAACGGCTTCCAGATCCTGGTCGAAGCAGGCCTCCTGCCCGGCGCGCTGATGCGCAACGCCTC
GCTGAAATTCGTCTGCCGAGAGGTGAAGCTGGAAGTCGTCAACTCGGACACGGCGTTTACCCGCGCCTACGCCAAAGGCC
AGGTGATCCGCAGCCCCGTTGCCCACCACGATGGCAACTATTTCGCCGATGCGGAAACGTTGAAGGCGGTAGAAGGCAAT
GGCCAGGTCGTGTTTCGCTATGCCGAAGGAACCAATCCCAACGGCTCCGTCAACGACATTGCAGGCATCATAAACGCGAA
GGGCAACGTGCTCGGAATGATGCCGCATCCGGAGAACCTGATCGAGTCAGCGCATGGCGGCGCCGACGGCCGGGGACTGT
TCGCCTCCGCGCTCGACGTCATCGCTGCCTGA

Upstream 100 bases:

>100_bases
ACAGCATTTCCCTCGCCTGACGGCGGGGGCGCCATTGCACTGCGTTGAAACGGCCCCGGAAGTCCTTATATGCCGGGGGC
AAAGGCAAGATAGGTACGTC

Downstream 100 bases:

>100_bases
TCTTCATTCACCGCGATTCCAGACGGAACCCGCACGCACATTTCCTGAAATTGCTTGGCCTTGTCTGAAATTGCTCCAGT
TGCTGCTGCAAGGCGGCATT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKSAVVQLPGLNRDRDMIAALTKISGSAPVTVWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIKARAEQGV
RVLGVCNGFQILVEAGLLPGALMRNASLKFVCREVKLEVVNSDTAFTRAYAKGQVIRSPVAHHDGNYFADAETLKAVEGN
GQVVFRYAEGTNPNGSVNDIAGIINAKGNVLGMMPHPENLIESAHGGADGRGLFASALDVIAA

Sequences:

>Translated_223_residues
MKSAVVQLPGLNRDRDMIAALTKISGSAPVTVWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIKARAEQGV
RVLGVCNGFQILVEAGLLPGALMRNASLKFVCREVKLEVVNSDTAFTRAYAKGQVIRSPVAHHDGNYFADAETLKAVEGN
GQVVFRYAEGTNPNGSVNDIAGIINAKGNVLGMMPHPENLIESAHGGADGRGLFASALDVIAA
>Mature_223_residues
MKSAVVQLPGLNRDRDMIAALTKISGSAPVTVWQTETEIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIKARAEQGV
RVLGVCNGFQILVEAGLLPGALMRNASLKFVCREVKLEVVNSDTAFTRAYAKGQVIRSPVAHHDGNYFADAETLKAVEGN
GQVVFRYAEGTNPNGSVNDIAGIINAKGNVLGMMPHPENLIESAHGGADGRGLFASALDVIAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=230, Percent_Identity=30.8695652173913, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582111, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24582109, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17137292, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23548; Mature: 23548

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVVQLPGLNRDRDMIAALTKISGSAPVTVWQTETEIPDVDLIVIPGGFSYGDYLRCG
CCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
AIAARMPVMQAIKARAEQGVRVLGVCNGFQILVEAGLLPGALMRNASLKFVCREVKLEVV
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHEEHHHCCCCHHHHHCCCHHEEEEEEEEEEE
NSDTAFTRAYAKGQVIRSPVAHHDGNYFADAETLKAVEGNGQVVFRYAEGTNPNGSVNDI
CCCCHHHHHHHCCCHHHCCHHHCCCCEEECHHHHEEECCCCEEEEEEECCCCCCCCHHHH
AGIINAKGNVLGMMPHPENLIESAHGGADGRGLFASALDVIAA
HHEEECCCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKSAVVQLPGLNRDRDMIAALTKISGSAPVTVWQTETEIPDVDLIVIPGGFSYGDYLRCG
CCCCEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHH
AIAARMPVMQAIKARAEQGVRVLGVCNGFQILVEAGLLPGALMRNASLKFVCREVKLEVV
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHEEHHHCCCCHHHHHCCCHHEEEEEEEEEEE
NSDTAFTRAYAKGQVIRSPVAHHDGNYFADAETLKAVEGNGQVVFRYAEGTNPNGSVNDI
CCCCHHHHHHHCCCHHHCCHHHCCCCEEECHHHHEEECCCCEEEEEEECCCCCCCCHHHH
AGIINAKGNVLGMMPHPENLIESAHGGADGRGLFASALDVIAA
HHEEECCCCEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]