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The map label for this gene is perR [H]

Identifier: 150396609

GI number: 150396609

Start: 1470631

End: 1471521

Strand: Direct

Name: perR [H]

Synonym: Smed_1395

Alternate gene names: 150396609

Gene position: 1470631-1471521 (Clockwise)

Preceding gene: 150396604

Following gene: 150396611

Centisome position: 38.89

GC content: 60.04

Gene sequence:

>891_bases
ATGAATAAAACTCAAACCAGGAACATGCGTCTTCCCCCGCTTGGTGCATTGCCGGCTTTCGCCGCTGCTGCGAAGGCTGG
AAGTCTGACTTCGGCGGCAGCCGAGATGCATGTGACTCCGGGAGCTGTAAGCCGCCAGGTCAAGTCGCTCGAACATGCGT
TGGGCGTGATGCTGTTTCGCCGCCGGCACAATGCTATAGAATTGACTGAGGCCGGGCGTCACTTCCTGGTCCACGTCAAC
AGTGCTCTTTCAACGCTCGAAACAGGGGCCCGGGCGATATTGCCTGATCGCTCTCGACTGGTGATCCAGGCACCGATTAC
GCTGGCGCGACGCTGGCTTATTCCGCGTCTGGGTTCCTATCTACATGAAAATCCGGCCGTCGACATTTCCATTCACTCGC
TGGCGCTTGGTTCCGGAGAAACGGCCGATGTGACGGTGACCTATCGGCGTGGTACGCAGATCGAAACATTCGCGCGAGGA
TCGCTGGTCGACAGGACCATTGCTGTTTCCTCGCCGCAACTGTTCTCCAGCCTCAGCGCAGGTCGCGAGCCGGGGCAGGT
TCTTGATCTGCCTCTGCTTCTGGACACGGCAGACGGCTGGTCCTGGCATCGCTGGTGCGAATGCGCCGGCTTTGCATTCG
AGCCGCGCGGCGGGACCCTAGTTTTCGATACGGATGAGGCCGCTATCGACGCTTGCATCTCTGGCCTGGGCGTCGGCCAG
GCCAATCCCTCATTCGTCGAGCGGGAGCTTCGCAGCGGGCAGCTTCTCGCTCTGTCTCCAACGTTGGCGCCGATCGTCGG
CGCTTATGAGATCGCAAAAGCACAGAGCGCTCGCCTGCCGCAAGGCTTTTTCGAATGGTTGTCGCGGTGGGATTTGCCGA
CACTTGCATGA

Upstream 100 bases:

>100_bases
TCGAAACAAGGACTCATGTGGACGCTATATTCCCCGAAATGAATTTGACTTATGAAGTCGATAGACATTTCCATTGCAAG
CGAAAGGTTTTCACGCCAGC

Downstream 100 bases:

>100_bases
CCGTGATCCGGCGCCCGTACAAAAAAAGGGCGCCCGGATCGATGACTCGGACGCCCTTTTCATTGAGGGAGTTGACGGTT
ACTGCTGCTTGGCAGCTTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Peroxide resistance protein perR [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNKTQTRNMRLPPLGALPAFAAAAKAGSLTSAAAEMHVTPGAVSRQVKSLEHALGVMLFRRRHNAIELTEAGRHFLVHVN
SALSTLETGARAILPDRSRLVIQAPITLARRWLIPRLGSYLHENPAVDISIHSLALGSGETADVTVTYRRGTQIETFARG
SLVDRTIAVSSPQLFSSLSAGREPGQVLDLPLLLDTADGWSWHRWCECAGFAFEPRGGTLVFDTDEAAIDACISGLGVGQ
ANPSFVERELRSGQLLALSPTLAPIVGAYEIAKAQSARLPQGFFEWLSRWDLPTLA

Sequences:

>Translated_296_residues
MNKTQTRNMRLPPLGALPAFAAAAKAGSLTSAAAEMHVTPGAVSRQVKSLEHALGVMLFRRRHNAIELTEAGRHFLVHVN
SALSTLETGARAILPDRSRLVIQAPITLARRWLIPRLGSYLHENPAVDISIHSLALGSGETADVTVTYRRGTQIETFARG
SLVDRTIAVSSPQLFSSLSAGREPGQVLDLPLLLDTADGWSWHRWCECAGFAFEPRGGTLVFDTDEAAIDACISGLGVGQ
ANPSFVERELRSGQLLALSPTLAPIVGAYEIAKAQSARLPQGFFEWLSRWDLPTLA
>Mature_296_residues
MNKTQTRNMRLPPLGALPAFAAAAKAGSLTSAAAEMHVTPGAVSRQVKSLEHALGVMLFRRRHNAIELTEAGRHFLVHVN
SALSTLETGARAILPDRSRLVIQAPITLARRWLIPRLGSYLHENPAVDISIHSLALGSGETADVTVTYRRGTQIETFARG
SLVDRTIAVSSPQLFSSLSAGREPGQVLDLPLLLDTADGWSWHRWCECAGFAFEPRGGTLVFDTDEAAIDACISGLGVGQ
ANPSFVERELRSGQLLALSPTLAPIVGAYEIAKAQSARLPQGFFEWLSRWDLPTLA

Specific function: Apparent regulatory gene involved in peroxide resistance in stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786448, Length=251, Percent_Identity=31.4741035856574, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789173, Length=286, Percent_Identity=29.7202797202797, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788706, Length=262, Percent_Identity=24.4274809160305, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=26.2798634812287, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787589, Length=280, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31937; Mature: 31937

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTQTRNMRLPPLGALPAFAAAAKAGSLTSAAAEMHVTPGAVSRQVKSLEHALGVMLFR
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
RRHNAIELTEAGRHFLVHVNSALSTLETGARAILPDRSRLVIQAPITLARRWLIPRLGSY
HCCCEEEEECCCCEEEEEEHHHHHHHHCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHH
LHENPAVDISIHSLALGSGETADVTVTYRRGTQIETFARGSLVDRTIAVSSPQLFSSLSA
HHCCCCEEEEEEEEEECCCCCEEEEEEEECCCEEEHHHCCCHHHHEEECCCHHHHHHHHC
GREPGQVLDLPLLLDTADGWSWHRWCECAGFAFEPRGGTLVFDTDEAAIDACISGLGVGQ
CCCCCCEEEEEEEEECCCCCCHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHCCCCC
ANPSFVERELRSGQLLALSPTLAPIVGAYEIAKAQSARLPQGFFEWLSRWDLPTLA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKTQTRNMRLPPLGALPAFAAAAKAGSLTSAAAEMHVTPGAVSRQVKSLEHALGVMLFR
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
RRHNAIELTEAGRHFLVHVNSALSTLETGARAILPDRSRLVIQAPITLARRWLIPRLGSY
HCCCEEEEECCCCEEEEEEHHHHHHHHCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHH
LHENPAVDISIHSLALGSGETADVTVTYRRGTQIETFARGSLVDRTIAVSSPQLFSSLSA
HHCCCCEEEEEEEEEECCCCCEEEEEEEECCCEEEHHHCCCHHHHEEECCCHHHHHHHHC
GREPGQVLDLPLLLDTADGWSWHRWCECAGFAFEPRGGTLVFDTDEAAIDACISGLGVGQ
CCCCCCEEEEEEEEECCCCCCHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHCCCCC
ANPSFVERELRSGQLLALSPTLAPIVGAYEIAKAQSARLPQGFFEWLSRWDLPTLA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]