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The map label for this gene is yebQ [C]

Identifier: 150396473

GI number: 150396473

Start: 1345464

End: 1346942

Strand: Direct

Name: yebQ [C]

Synonym: Smed_1255

Alternate gene names: 150396473

Gene position: 1345464-1346942 (Clockwise)

Preceding gene: 150396470

Following gene: 150396477

Centisome position: 35.58

GC content: 62.61

Gene sequence:

>1479_bases
ATGAGTTTAGCCGAAGAGAAATCGTCAATGGCCGATCCGGCGCAGCAGACTGTTACCAACGCGGAGGATGGGCGCTGGAG
CGAGCTGCTGCAGCCGCGTCACTTGGCGGCGACGGTGACACTGTGCCTTGGCGTAGCGCTTTTTGCCTTCAACGAGTTCT
TCGTGTCGACGGCGCTGCCCACAGCCGTTGTCGAGTTCGGGGGAGCCTCCCTCTTGTCCTGGGCGTTCACGCTGTATCTC
GTTTTCGCCATCGTCGGTGGCGCGCTGGCGGCGAATCAGAAAGCTCGATTCGGCGCACGCAACACACTGGTTGCGGCGGC
ACTCGTCTTCGCTACGGGCACGATCATCGCTACGATGGCGAGCAGCATGCCTCAGGTTCTTGCCGGGAGGGTTCTCCAGG
GGCTGGGCGAGGGCGTCATTGCAGCTCTATGCTACGCGCTGATACCGGAGCTTTTCCCGCAACGGCTGGTGCCCAAGATC
TTCGGAGCGGAAGCGATCGTGTGGGCTGGTGCCGCCTTCGGCGGCCCGCTCATATCCGGTTTGCTGACGGAATACTGGTC
GTGGCGCGCGGCCTTCTTCGTCAACATACCTGCGGCCGCAATCTTCGTTGTGCTCGTCGTCGCGATCGTGCGCCAGCCGG
CGCAAAGCCCGGGAGGGTCTGCCGGATCGATTCCCCTGCTGCGTCTGGTGACTTTCGGCGTCGGGATCTTGCTAGTCTCG
CTTTCAAGCACGGCGACCAACGATTATGCGATGGCGGGTTTGCTGGCGGCAGCGATCGCTGTGTTCGTCAGCACGGTCCG
ACTCGACCGCCGATCGCGGCAGTCTATTCTTCCTTTCGGAGCCTTTTCGCCCACCCACTCGCTCGGGGCCGGGCTCTGGG
TCATCCTTCTGATGCCGCTGGCGCAAGCCTCGGGCTCCGTTTACCTCGTCTACGCCCTGCAACAGCTATGGGGATTCGGC
CCGACTGCGGCTGGCTTCTCGAACGCCTTGATGGCCATATCCTGGAGCCTGACGGCGATACTCATCGCGAGCCTCCGCTC
TCATGAGATGCGCGTGCAGATCGTCTGGACCGGTCCGTTGATGCTATGCCTCGGCCTCGTTGGCTTGGCGCTGGCCGTCG
GAACCGGCGAATACAAGCTCGTCTTCATCAGCCAGGCTGCAATCGGAGCAGGTTTCGGCCTTTGCTGGGGGACGCTGAGC
CAGCTGCTGATGAACGTCTCGACCATAGAGGAACGCGACAAGACCTCCGCGCTGCTTCCGACGCTGCAATCGGCCGGTTA
CGCGATCGGCGCGGCGGTCTTCGGAGCCGTGGCCAATGCCGGAGGTTTCGATGAGGGCGCCAGCAATCGGGTGATATCGG
CGGCATTACTGGGTGTCTTTGCAGTTGGCGCAACTCTTGCGGCAGCATCGGTCTTCTTCGGGATCACGACCCTGCGGCTG
GCCCGATGCGAGGGCAAGGTTCACCAAAATATGCCGTAG

Upstream 100 bases:

>100_bases
CGTACTTGTAAAGGTGAAATTCGGCGGGGAAACCTCTTTACCTCAACCGTGATTGAGGTCGTATCAGTGCTGGTCCACGG
AAATCGATAGGGACCGAATC

Downstream 100 bases:

>100_bases
CGGCAAGGGAGCGGTTGCGGCCGAGAAGGGCATCCTGTTCGACGCCGCGGCCTTGGGATGGCGTGAGTGCCGCAAGCATC
ACGCCCGCCTCCGACCTTAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSLAEEKSSMADPAQQTVTNAEDGRWSELLQPRHLAATVTLCLGVALFAFNEFFVSTALPTAVVEFGGASLLSWAFTLYL
VFAIVGGALAANQKARFGARNTLVAAALVFATGTIIATMASSMPQVLAGRVLQGLGEGVIAALCYALIPELFPQRLVPKI
FGAEAIVWAGAAFGGPLISGLLTEYWSWRAAFFVNIPAAAIFVVLVVAIVRQPAQSPGGSAGSIPLLRLVTFGVGILLVS
LSSTATNDYAMAGLLAAAIAVFVSTVRLDRRSRQSILPFGAFSPTHSLGAGLWVILLMPLAQASGSVYLVYALQQLWGFG
PTAAGFSNALMAISWSLTAILIASLRSHEMRVQIVWTGPLMLCLGLVGLALAVGTGEYKLVFISQAAIGAGFGLCWGTLS
QLLMNVSTIEERDKTSALLPTLQSAGYAIGAAVFGAVANAGGFDEGASNRVISAALLGVFAVGATLAAASVFFGITTLRL
ARCEGKVHQNMP

Sequences:

>Translated_492_residues
MSLAEEKSSMADPAQQTVTNAEDGRWSELLQPRHLAATVTLCLGVALFAFNEFFVSTALPTAVVEFGGASLLSWAFTLYL
VFAIVGGALAANQKARFGARNTLVAAALVFATGTIIATMASSMPQVLAGRVLQGLGEGVIAALCYALIPELFPQRLVPKI
FGAEAIVWAGAAFGGPLISGLLTEYWSWRAAFFVNIPAAAIFVVLVVAIVRQPAQSPGGSAGSIPLLRLVTFGVGILLVS
LSSTATNDYAMAGLLAAAIAVFVSTVRLDRRSRQSILPFGAFSPTHSLGAGLWVILLMPLAQASGSVYLVYALQQLWGFG
PTAAGFSNALMAISWSLTAILIASLRSHEMRVQIVWTGPLMLCLGLVGLALAVGTGEYKLVFISQAAIGAGFGLCWGTLS
QLLMNVSTIEERDKTSALLPTLQSAGYAIGAAVFGAVANAGGFDEGASNRVISAALLGVFAVGATLAAASVFFGITTLRL
ARCEGKVHQNMP
>Mature_491_residues
SLAEEKSSMADPAQQTVTNAEDGRWSELLQPRHLAATVTLCLGVALFAFNEFFVSTALPTAVVEFGGASLLSWAFTLYLV
FAIVGGALAANQKARFGARNTLVAAALVFATGTIIATMASSMPQVLAGRVLQGLGEGVIAALCYALIPELFPQRLVPKIF
GAEAIVWAGAAFGGPLISGLLTEYWSWRAAFFVNIPAAAIFVVLVVAIVRQPAQSPGGSAGSIPLLRLVTFGVGILLVSL
SSTATNDYAMAGLLAAAIAVFVSTVRLDRRSRQSILPFGAFSPTHSLGAGLWVILLMPLAQASGSVYLVYALQQLWGFGP
TAAGFSNALMAISWSLTAILIASLRSHEMRVQIVWTGPLMLCLGLVGLALAVGTGEYKLVFISQAAIGAGFGLCWGTLSQ
LLMNVSTIEERDKTSALLPTLQSAGYAIGAAVFGAVANAGGFDEGASNRVISAALLGVFAVGATLAAASVFFGITTLRLA
RCEGKVHQNMP

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=428, Percent_Identity=24.0654205607477, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=173, Percent_Identity=28.3236994219653, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51106; Mature: 50975

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAEEKSSMADPAQQTVTNAEDGRWSELLQPRHLAATVTLCLGVALFAFNEFFVSTALP
CCCCHHHHHCCCHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVVEFGGASLLSWAFTLYLVFAIVGGALAANQKARFGARNTLVAAALVFATGTIIATMA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSMPQVLAGRVLQGLGEGVIAALCYALIPELFPQRLVPKIFGAEAIVWAGAAFGGPLISG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LLTEYWSWRAAFFVNIPAAAIFVVLVVAIVRQPAQSPGGSAGSIPLLRLVTFGVGILLVS
HHHHHHCCHHHEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSSTATNDYAMAGLLAAAIAVFVSTVRLDRRSRQSILPFGAFSPTHSLGAGLWVILLMPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AQASGSVYLVYALQQLWGFGPTAAGFSNALMAISWSLTAILIASLRSHEMRVQIVWTGPL
HHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHH
MLCLGLVGLALAVGTGEYKLVFISQAAIGAGFGLCWGTLSQLLMNVSTIEERDKTSALLP
HHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLQSAGYAIGAAVFGAVANAGGFDEGASNRVISAALLGVFAVGATLAAASVFFGITTLRL
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARCEGKVHQNMP
HHHHCCCCCCCC
>Mature Secondary Structure 
SLAEEKSSMADPAQQTVTNAEDGRWSELLQPRHLAATVTLCLGVALFAFNEFFVSTALP
CCCHHHHHCCCHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVVEFGGASLLSWAFTLYLVFAIVGGALAANQKARFGARNTLVAAALVFATGTIIATMA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSMPQVLAGRVLQGLGEGVIAALCYALIPELFPQRLVPKIFGAEAIVWAGAAFGGPLISG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
LLTEYWSWRAAFFVNIPAAAIFVVLVVAIVRQPAQSPGGSAGSIPLLRLVTFGVGILLVS
HHHHHHCCHHHEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSSTATNDYAMAGLLAAAIAVFVSTVRLDRRSRQSILPFGAFSPTHSLGAGLWVILLMPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AQASGSVYLVYALQQLWGFGPTAAGFSNALMAISWSLTAILIASLRSHEMRVQIVWTGPL
HHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHH
MLCLGLVGLALAVGTGEYKLVFISQAAIGAGFGLCWGTLSQLLMNVSTIEERDKTSALLP
HHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLQSAGYAIGAAVFGAVANAGGFDEGASNRVISAALLGVFAVGATLAAASVFFGITTLRL
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARCEGKVHQNMP
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]