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The map label for this gene is hcr [H]

Identifier: 150395709

GI number: 150395709

Start: 525471

End: 526565

Strand: Direct

Name: hcr [H]

Synonym: Smed_0484

Alternate gene names: 150395709

Gene position: 525471-526565 (Clockwise)

Preceding gene: 150395708

Following gene: 150395711

Centisome position: 13.89

GC content: 63.38

Gene sequence:

>1095_bases
ATGGAGATGCCTCGCGCCTTTCACCATTTCGACGAGCTCGACCCCTGGAGAGACCGGCAGCACATGCTGCAGTGCGTTTC
GGTGGCCACGGAGACGGCGGACGTCATGACCTTCACCTTCCGTTCCGACAAACCGGCCTGGTTCCGCTACCTGCCCGGGC
AATTCGTGACGCTCGAATTGCCCGTCGAAGAGGAGCCGGTGATGCGCACCTATACGCTGTCGTCCACGCCCTCGCGTCCG
CTTTCGATCGCGGTGACGGTAAAGGCCCAGCCGGGGAGCGTCGGTACCCGCTGGATGTTCGACAATCTGAAACCCGGCAT
GGTGCTGAAGGCGTTCGGGCCGTTGGGGGATTTCAGCTTCGTCCGTCATCCCGGTGAACGGTATCTCTTCATTTCGGCGG
GGTCGGGCATCACGCCGATGATATCGATGACACGCTGGATGGCCGACTGCGCGCCGGAATCGAATGTCACCTTCATCTCC
TGCGCCCGGCGCCCGGACGATCTCCTCTTCAAATACGAGCTGGAAGTTCTCGCGCGGCAGATGCCGCAGCTCAATCTCGG
CTTCCTCGTGGAAGGACACGAGGCGCGGCATGGCTGGCATGGACTGCGCGGCCGTCTCGACGCGACGAAGCTGCCGTTGC
TCGCTCCGGATTTCATGGAGAGAACCGTCTTCTGCTGCGGGCCGGAGCCGTTCATGGCCGGCGTACGGGACATGCTGGAG
ATGGCCGGCTTCCAAATGGAACGCTACCATCAGGAAAGCTTTCAGCCCGCAACTGCGCCTTCGGCCGGGGACCTCGCCAT
TCGGGAAGGACCGGCTGCGGACACCGAGGCCGGCGCGTCGCGGGTGACTTTCACCATGAGCGGCAAGGAGGCGCCAGCTC
TTCCCGGCCATACAGTTCTGCAAACAGCGCGCGCGAACGGAGTCAGGATCGGGGCCGCCTGCGAGGGCGGCATATGCGGA
ACCTGCCGGGTGATGAAGATCGCGGGCGACGTGGAAATGAACCATAATGGCGGCATTCTCGACGACGAGATCGAGGAGGG
TTACATTCTCGCCTGCTGCTCGCGGCCGATAGGCGACGTCCAGATCGAGGCCTGA

Upstream 100 bases:

>100_bases
AGCACGAGGGCGGCGTCATGCAGTTCGTCGAGTGGTATTCGAGTTTCATGCTGGACCGCCTTCAGGGCGGAGCCACGCAT
CTTTCGCGGGTCGCATGACC

Downstream 100 bases:

>100_bases
GTTACCGGCGCTCGGACTGGTAGGGAAGACGTGCCTCGGCAGCCCTGACGGCAATGGAACCCGTGACGGTCGTGTCGGCC
CTCGCTCCGGACCCGCTCTC

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MEMPRAFHHFDELDPWRDRQHMLQCVSVATETADVMTFTFRSDKPAWFRYLPGQFVTLELPVEEEPVMRTYTLSSTPSRP
LSIAVTVKAQPGSVGTRWMFDNLKPGMVLKAFGPLGDFSFVRHPGERYLFISAGSGITPMISMTRWMADCAPESNVTFIS
CARRPDDLLFKYELEVLARQMPQLNLGFLVEGHEARHGWHGLRGRLDATKLPLLAPDFMERTVFCCGPEPFMAGVRDMLE
MAGFQMERYHQESFQPATAPSAGDLAIREGPAADTEAGASRVTFTMSGKEAPALPGHTVLQTARANGVRIGAACEGGICG
TCRVMKIAGDVEMNHNGGILDDEIEEGYILACCSRPIGDVQIEA

Sequences:

>Translated_364_residues
MEMPRAFHHFDELDPWRDRQHMLQCVSVATETADVMTFTFRSDKPAWFRYLPGQFVTLELPVEEEPVMRTYTLSSTPSRP
LSIAVTVKAQPGSVGTRWMFDNLKPGMVLKAFGPLGDFSFVRHPGERYLFISAGSGITPMISMTRWMADCAPESNVTFIS
CARRPDDLLFKYELEVLARQMPQLNLGFLVEGHEARHGWHGLRGRLDATKLPLLAPDFMERTVFCCGPEPFMAGVRDMLE
MAGFQMERYHQESFQPATAPSAGDLAIREGPAADTEAGASRVTFTMSGKEAPALPGHTVLQTARANGVRIGAACEGGICG
TCRVMKIAGDVEMNHNGGILDDEIEEGYILACCSRPIGDVQIEA
>Mature_364_residues
MEMPRAFHHFDELDPWRDRQHMLQCVSVATETADVMTFTFRSDKPAWFRYLPGQFVTLELPVEEEPVMRTYTLSSTPSRP
LSIAVTVKAQPGSVGTRWMFDNLKPGMVLKAFGPLGDFSFVRHPGERYLFISAGSGITPMISMTRWMADCAPESNVTFIS
CARRPDDLLFKYELEVLARQMPQLNLGFLVEGHEARHGWHGLRGRLDATKLPLLAPDFMERTVFCCGPEPFMAGVRDMLE
MAGFQMERYHQESFQPATAPSAGDLAIREGPAADTEAGASRVTFTMSGKEAPALPGHTVLQTARANGVRIGAACEGGICG
TCRVMKIAGDVEMNHNGGILDDEIEEGYILACCSRPIGDVQIEA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=346, Percent_Identity=30.0578034682081, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787658, Length=356, Percent_Identity=29.2134831460674, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788104, Length=342, Percent_Identity=25.7309941520468, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788903, Length=249, Percent_Identity=25.7028112449799, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323552, Length=195, Percent_Identity=23.5897435897436, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40227; Mature: 40227

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMPRAFHHFDELDPWRDRQHMLQCVSVATETADVMTFTFRSDKPAWFRYLPGQFVTLEL
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHEEECCCEEEEEEC
PVEEEPVMRTYTLSSTPSRPLSIAVTVKAQPGSVGTRWMFDNLKPGMVLKAFGPLGDFSF
CCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEECCCCCCCHH
VRHPGERYLFISAGSGITPMISMTRWMADCAPESNVTFISCARRPDDLLFKYELEVLARQ
HCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHH
MPQLNLGFLVEGHEARHGWHGLRGRLDATKLPLLAPDFMERTVFCCGPEPFMAGVRDMLE
CCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCHHHHHHHHHHH
MAGFQMERYHQESFQPATAPSAGDLAIREGPAADTEAGASRVTFTMSGKEAPALPGHTVL
HHCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
QTARANGVRIGAACEGGICGTCRVMKIAGDVEMNHNGGILDDEIEEGYILACCSRPIGDV
HHHCCCCEEEECCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCCEEEEEECCCCCCE
QIEA
EEEC
>Mature Secondary Structure
MEMPRAFHHFDELDPWRDRQHMLQCVSVATETADVMTFTFRSDKPAWFRYLPGQFVTLEL
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHEEECCCEEEEEEC
PVEEEPVMRTYTLSSTPSRPLSIAVTVKAQPGSVGTRWMFDNLKPGMVLKAFGPLGDFSF
CCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEECCCCCCCHH
VRHPGERYLFISAGSGITPMISMTRWMADCAPESNVTFISCARRPDDLLFKYELEVLARQ
HCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHH
MPQLNLGFLVEGHEARHGWHGLRGRLDATKLPLLAPDFMERTVFCCGPEPFMAGVRDMLE
CCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCHHHHHHHHHHH
MAGFQMERYHQESFQPATAPSAGDLAIREGPAADTEAGASRVTFTMSGKEAPALPGHTVL
HHCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
QTARANGVRIGAACEGGICGTCRVMKIAGDVEMNHNGGILDDEIEEGYILACCSRPIGDV
HHHCCCCEEEECCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCCEEEEEECCCCCCE
QIEA
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]