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The map label for this gene is cheB1 [H]

Identifier: 150395465

GI number: 150395465

Start: 262280

End: 263329

Strand: Direct

Name: cheB1 [H]

Synonym: Smed_0238

Alternate gene names: 150395465

Gene position: 262280-263329 (Clockwise)

Preceding gene: 150395464

Following gene: 150395466

Centisome position: 6.94

GC content: 64.57

Gene sequence:

>1050_bases
ATGAGCGTTCCCGCACGTGTTCTCGTCGTCGACGACTCGGCCACCATGCGCGGCCTTATCTCGGCCGTGCTCAACGCCGA
CCCGGATATTACGGTCGTCGGCCAGGCTGCCGACGCGCTGGAGGCGCGCCAGGCGATCAAGCGGCTCGATCCCGATGTCG
TGACCCTCGATATCGAGATGCCGAACATGAATGGTCTCGAATTCCTCGACAAGATCATGCGACTGAGGCCGATGCCGGTG
CTCATGGTTTCGACGCTTACCCAGAGGGGTGCCGAAGCAACGATCGCCGCGCTCGAGATCGGCGCCTTCGACTGCGTCGG
CAAGCCCCGGCCGGGGGATCCGCATCCGTTCGGCGATCTCGCCGATAAGGTCAAGGCGGCCGCCCGTTCGCAGCGCAAGG
CCATGATCACCAGCAACAGGACGGCTGCGCCGGCCGTGGCGACGGCTTCCGACTACCGGGCAGGGCGCAAGATCATCGCG
ATCGGCGCCTCGACTGGTGGGGTCGAGGCCCTGATCACGGTGCTGCAGAAGTTCCCGGCGAATTGCCCGCCGACGGTGAT
AACCCAGCACATGCCGCACACCTTCACCAAGAGTTTCGCCGAACGGCTGAACCGTCTTTGCGCCCCGACCGTACAGGAGG
CGACGGATGGCGCCCGGCTCGAAATCGGCAGGGTCTACCTGGCTCCGGGCGGCGAACGGCATCTTCAGGTCGCCAACGCG
TCCGCACCGTGCTGCCGTCTCGTCGATCACCCGCCGGTCAACGGACATCGTCCCTCGGTCGACGTTCTGTTCGATTCGGT
CGCCGAACTGGCCGGGCGGAACGCCATCGGGGTGATCTTGACCGGAATGGGCCGCGACGGTGCCGCCGGACTTCTGAAAT
TGCGGCATGCCGGAGCACGCACCTTCGGCCAGAACGAAAAGACCTCAGTCGTCTACGGCATGCCGCGCGTCGCCTATGAA
TTGGGTGCTGTCGAAACGCAGCTCCCCCTCGGATCGATCGGGGAGGAGATATTGAAGACGGCGGCAGCCCGAAAAGAAGG
AATGGAATAA

Upstream 100 bases:

>100_bases
GCGTATCGGGTGACGCCAAAAGTCTATTCGACAATATCGGCATCACGACCTACCGCCATACCGGCAGGTTCCACACAGGC
CGGTTCCACGGAGATACGGC

Downstream 100 bases:

>100_bases
TGTCCCTCGCCGAAAAGATAAAAGTTCTGATCGTCGACGATCAGGTCACGAGCCGGCTGCTGTTGGGCGATGCGCTCCAG
CAACTGGGCTTCAAGCAGAT

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSVPARVLVVDDSATMRGLISAVLNADPDITVVGQAADALEARQAIKRLDPDVVTLDIEMPNMNGLEFLDKIMRLRPMPV
LMVSTLTQRGAEATIAALEIGAFDCVGKPRPGDPHPFGDLADKVKAAARSQRKAMITSNRTAAPAVATASDYRAGRKIIA
IGASTGGVEALITVLQKFPANCPPTVITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEIGRVYLAPGGERHLQVANA
SAPCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHAGARTFGQNEKTSVVYGMPRVAYE
LGAVETQLPLGSIGEEILKTAAARKEGME

Sequences:

>Translated_349_residues
MSVPARVLVVDDSATMRGLISAVLNADPDITVVGQAADALEARQAIKRLDPDVVTLDIEMPNMNGLEFLDKIMRLRPMPV
LMVSTLTQRGAEATIAALEIGAFDCVGKPRPGDPHPFGDLADKVKAAARSQRKAMITSNRTAAPAVATASDYRAGRKIIA
IGASTGGVEALITVLQKFPANCPPTVITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEIGRVYLAPGGERHLQVANA
SAPCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHAGARTFGQNEKTSVVYGMPRVAYE
LGAVETQLPLGSIGEEILKTAAARKEGME
>Mature_348_residues
SVPARVLVVDDSATMRGLISAVLNADPDITVVGQAADALEARQAIKRLDPDVVTLDIEMPNMNGLEFLDKIMRLRPMPVL
MVSTLTQRGAEATIAALEIGAFDCVGKPRPGDPHPFGDLADKVKAAARSQRKAMITSNRTAAPAVATASDYRAGRKIIAI
GASTGGVEALITVLQKFPANCPPTVITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEIGRVYLAPGGERHLQVANAS
APCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHAGARTFGQNEKTSVVYGMPRVAYEL
GAVETQLPLGSIGEEILKTAAARKEGME

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=340, Percent_Identity=49.7058823529412, Blast_Score=322, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 36949; Mature: 36818

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPARVLVVDDSATMRGLISAVLNADPDITVVGQAADALEARQAIKRLDPDVVTLDIEM
CCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEC
PNMNGLEFLDKIMRLRPMPVLMVSTLTQRGAEATIAALEIGAFDCVGKPRPGDPHPFGDL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHH
ADKVKAAARSQRKAMITSNRTAAPAVATASDYRAGRKIIAIGASTGGVEALITVLQKFPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHCCC
NCPPTVITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEIGRVYLAPGGERHLQVANA
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEEEECCCCCCEEEEECC
SAPCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHAGAR
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCH
TFGQNEKTSVVYGMPRVAYELGAVETQLPLGSIGEEILKTAAARKEGME
HCCCCCCCEEEECCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVPARVLVVDDSATMRGLISAVLNADPDITVVGQAADALEARQAIKRLDPDVVTLDIEM
CCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEC
PNMNGLEFLDKIMRLRPMPVLMVSTLTQRGAEATIAALEIGAFDCVGKPRPGDPHPFGDL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHH
ADKVKAAARSQRKAMITSNRTAAPAVATASDYRAGRKIIAIGASTGGVEALITVLQKFPA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHCCC
NCPPTVITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEIGRVYLAPGGERHLQVANA
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEEEECCCCCCEEEEECC
SAPCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHAGAR
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCH
TFGQNEKTSVVYGMPRVAYELGAVETQLPLGSIGEEILKTAAARKEGME
HCCCCCCCEEEECCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]