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The map label for this gene is mcpE [H]

Identifier: 150395459

GI number: 150395459

Start: 256305

End: 257903

Strand: Direct

Name: mcpE [H]

Synonym: Smed_0232

Alternate gene names: 150395459

Gene position: 256305-257903 (Clockwise)

Preceding gene: 150395457

Following gene: 150395460

Centisome position: 6.78

GC content: 64.98

Gene sequence:

>1599_bases
GTGAAACAGGAAGCGTCAGAACAGGCGAGAAGGGGTCAGGCGGCCAGTCTGCTGGAACGCTTGCGCTTTGCCGGTCTCGA
CGAAGATGCCTGCGCGCTGCTTCGCGATCACCGGCAGGCTCTTTCGCCACGCATCGAGCTTGCGCTGCGTGCACTCTCGC
ACCGCCTGCAGACCCATCCCGACGCGGCGCGTCATTTCGACAGCGACCGACAGGTCGACCGTCTTCACGATCTGCAATCA
TCGCACTGGAATGTGCTCACGGACGCCCGTTTCGACGGCCTTTATGCCGAGCGAGTGAAGGTGCTTGCCGACACCGAGAG
CCGCATGGGTCTCGACCCGCGCTGGCAGATTGCAAGCCACGCCGTCGTGCTCGAGCACCTGATCATGGGCGCGATCGAGG
ACGCCTGGCCGAAATCGATCATCTCCCTCGGCAAAGCTCGCAAGAAGGAACTGCGCGACCTGGTCGCTGCGCTCGTGCGC
ACCGCATTCGTCGATACCGAAATTGCGGTCTCCCTCCGCTTCAACGCGTTGCGCCAGCAGCACCAGCGGCAGCTTTCCCA
GAGCCGGCGGGACGGCGAAGCCGAGCTGCAGGCGCTCTTCGCGGATTTCCTGAATGCTCTCGCGGAGGGCGACCTAACCG
CGCGGCTTCCCGAGGATGCGCCGGAAACCTACATGCCCATCGTCGCGGGCCTCAACACGGCACTGGGCGAGATCAGGAAT
GCGCTGCTCGCGGCGGATGAACGCGCCGCGGCGGCCGAGGCCATCGTCTCGGATCTGCGCGGCAGCGCCGCCGATTTATC
GAGCAAAGCCGGGGCAGAGGTGAAAACGCTCGATCAGCATCTCGCGACCCTCGTCAGCGCGACCGAGCGTATTCGCTCCG
GTTCGATCCGTATCGGCGCCACCGAGGCCAAGGCAAGCGAGACCCGCATTGCGGTGGAGCGCAGCGGCGAGATCGCCGGC
CAGGCGATCTCTGCCATGGCGGACATCGAAGCGTCTGCCGAAAAAATCGGGCAGATCATCGGCGTCATCGACGAGATCGC
CTTCCAGACCAACCTCCTGGCTCTCAATGCGGGCATCGAAGCGGCCCGGGCAGGCGAAAGCGGTCGCGGTTTCGCGGTTG
TCGCACAGGAGGTGCGTGCGCTCGCGCAACGGTCCGGCGAAGCCGCGCGCGAGATCAAGCAGCTCGTGACAGGAACGAAA
GGCCAGGTCGCGGCCGGCGTCGAGACCGTCGGACGGACCCAGCACGCCATCAGCAGCATCGCCGAACAGGTCATTTCCAT
AAACGAGGCCGTCACCGGCATCGCACGTGAGGCGGAATATCAGGTGAGGGATCTTTCCTCCGCAGCCTCGGAAATCGGCG
CGGTCGCCGAGGCGATGAACCGAAGCACCGCACTCGCGGAGGTGGCACTGGCGTCCTCCGGCGACCTTCACGACGTCATT
ATGGAACTGGGCGAGACCGTCCGTCGCTTCCATCTCGAGCGTGAGGCGAGATCGGGCGCGCGCTTCTTACCGTCAAGAGT
AGAGGCGACCGACGACCAAAACGAAATGCCGTTCGGCGAGGCCGCGTCCGAACGGCACTTCGCCGGATGGCGACGTTAG

Upstream 100 bases:

>100_bases
GAGCGCGCTGTTCTCATCGCTTGCGTGTGACCGGCCGCCGGCTGCGATCCTCTTCCCGGGACGATTTCTATCAGGCGCGC
GTCAATAGCCGGGGACCAGC

Downstream 100 bases:

>100_bases
TGCACGCACTTGAAGCGAGGGAAAAATGGCCAGCAGAAACACCGCAGGAAAAACACTGAAGCTCGCTCCGGTATTGGACC
TGAACGAGGCAACGGTGCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MKQEASEQARRGQAASLLERLRFAGLDEDACALLRDHRQALSPRIELALRALSHRLQTHPDAARHFDSDRQVDRLHDLQS
SHWNVLTDARFDGLYAERVKVLADTESRMGLDPRWQIASHAVVLEHLIMGAIEDAWPKSIISLGKARKKELRDLVAALVR
TAFVDTEIAVSLRFNALRQQHQRQLSQSRRDGEAELQALFADFLNALAEGDLTARLPEDAPETYMPIVAGLNTALGEIRN
ALLAADERAAAAEAIVSDLRGSAADLSSKAGAEVKTLDQHLATLVSATERIRSGSIRIGATEAKASETRIAVERSGEIAG
QAISAMADIEASAEKIGQIIGVIDEIAFQTNLLALNAGIEAARAGESGRGFAVVAQEVRALAQRSGEAAREIKQLVTGTK
GQVAAGVETVGRTQHAISSIAEQVISINEAVTGIAREAEYQVRDLSSAASEIGAVAEAMNRSTALAEVALASSGDLHDVI
MELGETVRRFHLEREARSGARFLPSRVEATDDQNEMPFGEAASERHFAGWRR

Sequences:

>Translated_532_residues
MKQEASEQARRGQAASLLERLRFAGLDEDACALLRDHRQALSPRIELALRALSHRLQTHPDAARHFDSDRQVDRLHDLQS
SHWNVLTDARFDGLYAERVKVLADTESRMGLDPRWQIASHAVVLEHLIMGAIEDAWPKSIISLGKARKKELRDLVAALVR
TAFVDTEIAVSLRFNALRQQHQRQLSQSRRDGEAELQALFADFLNALAEGDLTARLPEDAPETYMPIVAGLNTALGEIRN
ALLAADERAAAAEAIVSDLRGSAADLSSKAGAEVKTLDQHLATLVSATERIRSGSIRIGATEAKASETRIAVERSGEIAG
QAISAMADIEASAEKIGQIIGVIDEIAFQTNLLALNAGIEAARAGESGRGFAVVAQEVRALAQRSGEAAREIKQLVTGTK
GQVAAGVETVGRTQHAISSIAEQVISINEAVTGIAREAEYQVRDLSSAASEIGAVAEAMNRSTALAEVALASSGDLHDVI
MELGETVRRFHLEREARSGARFLPSRVEATDDQNEMPFGEAASERHFAGWRR
>Mature_532_residues
MKQEASEQARRGQAASLLERLRFAGLDEDACALLRDHRQALSPRIELALRALSHRLQTHPDAARHFDSDRQVDRLHDLQS
SHWNVLTDARFDGLYAERVKVLADTESRMGLDPRWQIASHAVVLEHLIMGAIEDAWPKSIISLGKARKKELRDLVAALVR
TAFVDTEIAVSLRFNALRQQHQRQLSQSRRDGEAELQALFADFLNALAEGDLTARLPEDAPETYMPIVAGLNTALGEIRN
ALLAADERAAAAEAIVSDLRGSAADLSSKAGAEVKTLDQHLATLVSATERIRSGSIRIGATEAKASETRIAVERSGEIAG
QAISAMADIEASAEKIGQIIGVIDEIAFQTNLLALNAGIEAARAGESGRGFAVVAQEVRALAQRSGEAAREIKQLVTGTK
GQVAAGVETVGRTQHAISSIAEQVISINEAVTGIAREAEYQVRDLSSAASEIGAVAEAMNRSTALAEVALASSGDLHDVI
MELGETVRRFHLEREARSGARFLPSRVEATDDQNEMPFGEAASERHFAGWRR

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=232, Percent_Identity=39.2241379310345, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787690, Length=242, Percent_Identity=33.4710743801653, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788194, Length=300, Percent_Identity=32.3333333333333, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1788195, Length=215, Percent_Identity=38.1395348837209, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789453, Length=174, Percent_Identity=37.3563218390805, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57546; Mature: 57546

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQEASEQARRGQAASLLERLRFAGLDEDACALLRDHRQALSPRIELALRALSHRLQTHP
CCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
DAARHFDSDRQVDRLHDLQSSHWNVLTDARFDGLYAERVKVLADTESRMGLDPRWQIASH
HHHHHCCCCHHHHHHHHHHHCCCCEEECCHHCCHHHHHHHHHHCCHHHCCCCCCHHHHHH
AVVLEHLIMGAIEDAWPKSIISLGKARKKELRDLVAALVRTAFVDTEIAVSLRFNALRQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQRQLSQSRRDGEAELQALFADFLNALAEGDLTARLPEDAPETYMPIVAGLNTALGEIRN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLAADERAAAAEAIVSDLRGSAADLSSKAGAEVKTLDQHLATLVSATERIRSGSIRIGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEC
TEAKASETRIAVERSGEIAGQAISAMADIEASAEKIGQIIGVIDEIAFQTNLLALNAGIE
CCCCCCHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCH
AARAGESGRGFAVVAQEVRALAQRSGEAAREIKQLVTGTKGQVAAGVETVGRTQHAISSI
HHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEQVISINEAVTGIAREAEYQVRDLSSAASEIGAVAEAMNRSTALAEVALASSGDLHDVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MELGETVRRFHLEREARSGARFLPSRVEATDDQNEMPFGEAASERHFAGWRR
HHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQEASEQARRGQAASLLERLRFAGLDEDACALLRDHRQALSPRIELALRALSHRLQTHP
CCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
DAARHFDSDRQVDRLHDLQSSHWNVLTDARFDGLYAERVKVLADTESRMGLDPRWQIASH
HHHHHCCCCHHHHHHHHHHHCCCCEEECCHHCCHHHHHHHHHHCCHHHCCCCCCHHHHHH
AVVLEHLIMGAIEDAWPKSIISLGKARKKELRDLVAALVRTAFVDTEIAVSLRFNALRQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQRQLSQSRRDGEAELQALFADFLNALAEGDLTARLPEDAPETYMPIVAGLNTALGEIRN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLAADERAAAAEAIVSDLRGSAADLSSKAGAEVKTLDQHLATLVSATERIRSGSIRIGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEC
TEAKASETRIAVERSGEIAGQAISAMADIEASAEKIGQIIGVIDEIAFQTNLLALNAGIE
CCCCCCHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCH
AARAGESGRGFAVVAQEVRALAQRSGEAAREIKQLVTGTKGQVAAGVETVGRTQHAISSI
HHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEQVISINEAVTGIAREAEYQVRDLSSAASEIGAVAEAMNRSTALAEVALASSGDLHDVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MELGETVRRFHLEREARSGARFLPSRVEATDDQNEMPFGEAASERHFAGWRR
HHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]