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The map label for this gene is secD [H]

Identifier: 150395408

GI number: 150395408

Start: 199089

End: 201623

Strand: Direct

Name: secD [H]

Synonym: Smed_0181

Alternate gene names: 150395408

Gene position: 199089-201623 (Clockwise)

Preceding gene: 150395407

Following gene: 150395409

Centisome position: 5.26

GC content: 62.72

Gene sequence:

>2535_bases
ATGCATACATCCAGATGGGCGGTTCTCGCCTATGTCGCAATTATCATCTTCGGATGCCTTGCGGCGCTGCCGAGCGTGCT
GACGCCGGCCATGAGGGAGCAGGTCGCTTCCGTTCTCCCGTTCGAGCCGGTCACGCTCGGCCTCGACCTGAGGGGCGGCT
CGCACCTCGTCCTCGAAGTCGACGGGGCGGGGCTTCAGAAAGCCCGCCTCAACTCGCTTCTCGACGATACCCGCCGCGTC
TTGCGCGGTGAGCGCGTATCCGCCTCCTCGGCGCGTATCAGCGGCAATGGCGTCACCGTGAGCATTCCCGATGCTCAGGA
CCGGGACAAGGTTCTGCCGAAGCTGCAGGAATTGGCAACGCCCGTAAGCACGGTCGGTTTTGCCGCCAGTGCTCCTGAAG
TCGAAGTATCGACGACGGGCGATGTGATTACCTTGGGCATGACCGAGGCGGGTCTTGCCGACCGCATGACCAAGGCGGTC
GAGCAGAGCCTGGAAATCATTCGCAACCGTGTCGACCAGGTCGGCGTTGCCGAGCCGCTGATCCAGCGGATCGGTTCCAA
CCGCATACTGGTTCAGCTCCCCGGTCTCCAGGATCCGACACGCCTGCGTGAGCTTCTCGGCTCCACGGCACAGATGAGCT
TCCACATGCTCGACCAGAGCGTGGATGTGACCCAGCCGGCTCCGCGTGGGGTGGACATTCTGCCCGGCGCCGACGATGGC
AACCGCTACGCGGTCGAGACCCGCATTGCCATTTCCGGAGAGCGGCTCGAAGATGCCAAGGTCGGCTTCGACCAGCGCAC
CAATCAGCCGGTCGTGGATTTCACCTTCGACTCGCTCGGAGCCCGGCAGTTTGCCGACATCACCCGCGAAAATGTCGGGC
GGCCTTTCGCCATCGTGCTCGACGGCAAGGTGTTGACGGCGCCCGTCATCAATGAGCCGATCCTTGGTGGCCGCGGTCAG
ATCAGCGGCAGCTTTACCGTCGAGGAGGCAACGGTTCTTTCCGCACTCCTGCGCTCCGGTGCACTGCCCGCCCCGCTGAC
CATTATCGAAGAGCGCTCCGTCGGCCCCAATCTCGGCAGCGACTCGATTCGCATGGGCCTCTTTACCGGTCTCGCCGGTT
TCGGCCTCGTGGTCGTCCTCATGGTCGTCCTTTACGGGGCCTGGGGTATGATCGCCAATGTCGGCCTGGTTCTGCACACG
ATCATGACGATCGGCATCCTCGGCCTCATAGGCTCGACGCTGACCTTGCCCGGCATCGCCGGTATCATCCTCGGCATCGG
CATGGCCGTCGACGCCAACATCCTTATCAATGCCCGTATCCGGGAAGAGACCGAGGCGGGTGCCGGCGCGATGAAGGCGC
TCGATATCGGCTTCAACAAGGCCTATGCGACGATCATCGACTCCAACGTCACGACGCTTGCGGGCACGGTCCTTCTGTTC
TGGTTCGGCAGCGGCCCGGTCAAGGGGTTCGCCGTCACCATGATGCTCGGCATCGGTATCTCGATGTTCACATCCGTTAC
CGTCGTGCGTCTTCTGATGCGCGAGGTTGTCGTTCGCCGGAAGATGAAGAAGCTCGTGATACCGTCGCTCTTCGGTCCGG
TGCCGCGCCTGCCGAGCTTCTCCTTCATGAAAGGCCGTTTCCTGGCGATAGGCTTTTCGGCTTTCCTGTCGATCAGTTCG
GTGGTTCTGTTCTTCACACCCGGCCTGAATTACGGCATCGATTTCATCGGCGGCATTCAGGTGGAGGCGGTCTCCAAGGA
GAAGATCGACCTGGCGACGCTCCGGCGAAGCGTCGAGGAGCTCAATCTCGGCGAGGTGGCCCTGCAGGACTTCGGTGGCG
GGCAATCGGTGTTGATCCGCGTGCAGCGCCAGCCGGGCGGCGAGCAGGCGCAGAGCCTGGCCCTGAACAAGGTCAAGGAT
GCCGTGACGACCGCCATCCCCGGCGCCAGCATGGAGCGGACCGAGGTCGTAGGTCCCACGGTCAGCGGCGAACTGGCTCG
ATCGGGCTTCCTCGCCGTGGCACTCGCCATGGTTGCGATCCTGCTCTACATCTGGTTCCGCTTCGAATGGCACTTCGCCG
TCGGCGCTATCGCCGTGCTGTTGCTCGACATCACCAAAACCGTCGGATTCTTTGCTCTTACGGGCATCGACTTCAATCTG
ACCGCGATCGCCGCGCTGCTGACGATGATCGGCTATTCGGTCAACGACAAGGTGGTGGTCTATGACCGCATGCGCGAAAA
CCTGCGCAGGTACAAATCGATGGCGTTCTCGGATCTGATCGACTTGAGCATCAATCAGGTGATCGCGCGATGCATCTTCA
CCTCCGCAGCGACGGCGCTGTCGCTGGTTCCGATGGCCATCTGGGGCGGCGAGGCGGTGCAGAGCTTCGCCTGGCCGATG
ATCTTCGGCGTCATCGTCGCGACGACGTCGTCCATCTATATCGGCGGTCCGATCCTGCTGTTCCTGAGCCGTTGGTGGAA
AGAGCGGGAAGCCGCTCGTTCCGGCGGACAGCAGGCGGAAACGCCGACCGCCTGA

Upstream 100 bases:

>100_bases
TTTGAGAGTTCGGCAGGTCTTTCGCGCCCGCCTCAGCCATTGATGAAAACCCGGCCCGGATGCTGCCCATGGCGCGTTCT
GGCGTTTATGGAATTCCCAC

Downstream 100 bases:

>100_bases
TCAGGATCAGAGCGCTTCAACGTTCTGTTGAATCCGTGAAACGCATCTCGTGCCAGGGGCAGCCTCCGATGGGGCTGCCC
CTTTTTCGTCGGAAAGTCCT

Product: bifunctional preprotein translocase subunit SecD/SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MHTSRWAVLAYVAIIIFGCLAALPSVLTPAMREQVASVLPFEPVTLGLDLRGGSHLVLEVDGAGLQKARLNSLLDDTRRV
LRGERVSASSARISGNGVTVSIPDAQDRDKVLPKLQELATPVSTVGFAASAPEVEVSTTGDVITLGMTEAGLADRMTKAV
EQSLEIIRNRVDQVGVAEPLIQRIGSNRILVQLPGLQDPTRLRELLGSTAQMSFHMLDQSVDVTQPAPRGVDILPGADDG
NRYAVETRIAISGERLEDAKVGFDQRTNQPVVDFTFDSLGARQFADITRENVGRPFAIVLDGKVLTAPVINEPILGGRGQ
ISGSFTVEEATVLSALLRSGALPAPLTIIEERSVGPNLGSDSIRMGLFTGLAGFGLVVVLMVVLYGAWGMIANVGLVLHT
IMTIGILGLIGSTLTLPGIAGIILGIGMAVDANILINARIREETEAGAGAMKALDIGFNKAYATIIDSNVTTLAGTVLLF
WFGSGPVKGFAVTMMLGIGISMFTSVTVVRLLMREVVVRRKMKKLVIPSLFGPVPRLPSFSFMKGRFLAIGFSAFLSISS
VVLFFTPGLNYGIDFIGGIQVEAVSKEKIDLATLRRSVEELNLGEVALQDFGGGQSVLIRVQRQPGGEQAQSLALNKVKD
AVTTAIPGASMERTEVVGPTVSGELARSGFLAVALAMVAILLYIWFRFEWHFAVGAIAVLLLDITKTVGFFALTGIDFNL
TAIAALLTMIGYSVNDKVVVYDRMRENLRRYKSMAFSDLIDLSINQVIARCIFTSAATALSLVPMAIWGGEAVQSFAWPM
IFGVIVATTSSIYIGGPILLFLSRWWKEREAARSGGQQAETPTA

Sequences:

>Translated_844_residues
MHTSRWAVLAYVAIIIFGCLAALPSVLTPAMREQVASVLPFEPVTLGLDLRGGSHLVLEVDGAGLQKARLNSLLDDTRRV
LRGERVSASSARISGNGVTVSIPDAQDRDKVLPKLQELATPVSTVGFAASAPEVEVSTTGDVITLGMTEAGLADRMTKAV
EQSLEIIRNRVDQVGVAEPLIQRIGSNRILVQLPGLQDPTRLRELLGSTAQMSFHMLDQSVDVTQPAPRGVDILPGADDG
NRYAVETRIAISGERLEDAKVGFDQRTNQPVVDFTFDSLGARQFADITRENVGRPFAIVLDGKVLTAPVINEPILGGRGQ
ISGSFTVEEATVLSALLRSGALPAPLTIIEERSVGPNLGSDSIRMGLFTGLAGFGLVVVLMVVLYGAWGMIANVGLVLHT
IMTIGILGLIGSTLTLPGIAGIILGIGMAVDANILINARIREETEAGAGAMKALDIGFNKAYATIIDSNVTTLAGTVLLF
WFGSGPVKGFAVTMMLGIGISMFTSVTVVRLLMREVVVRRKMKKLVIPSLFGPVPRLPSFSFMKGRFLAIGFSAFLSISS
VVLFFTPGLNYGIDFIGGIQVEAVSKEKIDLATLRRSVEELNLGEVALQDFGGGQSVLIRVQRQPGGEQAQSLALNKVKD
AVTTAIPGASMERTEVVGPTVSGELARSGFLAVALAMVAILLYIWFRFEWHFAVGAIAVLLLDITKTVGFFALTGIDFNL
TAIAALLTMIGYSVNDKVVVYDRMRENLRRYKSMAFSDLIDLSINQVIARCIFTSAATALSLVPMAIWGGEAVQSFAWPM
IFGVIVATTSSIYIGGPILLFLSRWWKEREAARSGGQQAETPTA
>Mature_844_residues
MHTSRWAVLAYVAIIIFGCLAALPSVLTPAMREQVASVLPFEPVTLGLDLRGGSHLVLEVDGAGLQKARLNSLLDDTRRV
LRGERVSASSARISGNGVTVSIPDAQDRDKVLPKLQELATPVSTVGFAASAPEVEVSTTGDVITLGMTEAGLADRMTKAV
EQSLEIIRNRVDQVGVAEPLIQRIGSNRILVQLPGLQDPTRLRELLGSTAQMSFHMLDQSVDVTQPAPRGVDILPGADDG
NRYAVETRIAISGERLEDAKVGFDQRTNQPVVDFTFDSLGARQFADITRENVGRPFAIVLDGKVLTAPVINEPILGGRGQ
ISGSFTVEEATVLSALLRSGALPAPLTIIEERSVGPNLGSDSIRMGLFTGLAGFGLVVVLMVVLYGAWGMIANVGLVLHT
IMTIGILGLIGSTLTLPGIAGIILGIGMAVDANILINARIREETEAGAGAMKALDIGFNKAYATIIDSNVTTLAGTVLLF
WFGSGPVKGFAVTMMLGIGISMFTSVTVVRLLMREVVVRRKMKKLVIPSLFGPVPRLPSFSFMKGRFLAIGFSAFLSISS
VVLFFTPGLNYGIDFIGGIQVEAVSKEKIDLATLRRSVEELNLGEVALQDFGGGQSVLIRVQRQPGGEQAQSLALNKVKD
AVTTAIPGASMERTEVVGPTVSGELARSGFLAVALAMVAILLYIWFRFEWHFAVGAIAVLLLDITKTVGFFALTGIDFNL
TAIAALLTMIGYSVNDKVVVYDRMRENLRRYKSMAFSDLIDLSINQVIARCIFTSAATALSLVPMAIWGGEAVQSFAWPM
IFGVIVATTSSIYIGGPILLFLSRWWKEREAARSGGQQAETPTA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=532, Percent_Identity=35.9022556390977, Blast_Score=312, Evalue=6e-86,
Organism=Escherichia coli, GI1786610, Length=283, Percent_Identity=32.5088339222615, Blast_Score=183, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 90189; Mature: 90189

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSRWAVLAYVAIIIFGCLAALPSVLTPAMREQVASVLPFEPVTLGLDLRGGSHLVLEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
DGAGLQKARLNSLLDDTRRVLRGERVSASSARISGNGVTVSIPDAQDRDKVLPKLQELAT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHC
PVSTVGFAASAPEVEVSTTGDVITLGMTEAGLADRMTKAVEQSLEIIRNRVDQVGVAEPL
CHHHHCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IQRIGSNRILVQLPGLQDPTRLRELLGSTAQMSFHMLDQSVDVTQPAPRGVDILPGADDG
HHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCC
NRYAVETRIAISGERLEDAKVGFDQRTNQPVVDFTFDSLGARQFADITRENVGRPFAIVL
CEEEEEEEEEECCCCCCHHHCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHCCCCEEEEE
DGKVLTAPVINEPILGGRGQISGSFTVEEATVLSALLRSGALPAPLTIIEERSVGPNLGS
CCCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
DSIRMGLFTGLAGFGLVVVLMVVLYGAWGMIANVGLVLHTIMTIGILGLIGSTLTLPGIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIILGIGMAVDANILINARIREETEAGAGAMKALDIGFNKAYATIIDSNVTTLAGTVLLF
HHHHHHHHHCCCEEEEEEEECHHHHCCCCHHHHEECCCCCEEEEEECCCHHHHHHHHHHE
WFGSGPVKGFAVTMMLGIGISMFTSVTVVRLLMREVVVRRKMKKLVIPSLFGPVPRLPSF
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SFMKGRFLAIGFSAFLSISSVVLFFTPGLNYGIDFIGGIQVEAVSKEKIDLATLRRSVEE
HHHCCCHHEEHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LNLGEVALQDFGGGQSVLIRVQRQPGGEQAQSLALNKVKDAVTTAIPGASMERTEVVGPT
CCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCC
VSGELARSGFLAVALAMVAILLYIWFRFEWHFAVGAIAVLLLDITKTVGFFALTGIDFNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCH
TAIAALLTMIGYSVNDKVVVYDRMRENLRRYKSMAFSDLIDLSINQVIARCIFTSAATAL
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVPMAIWGGEAVQSFAWPMIFGVIVATTSSIYIGGPILLFLSRWWKEREAARSGGQQAE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
TPTA
CCCC
>Mature Secondary Structure
MHTSRWAVLAYVAIIIFGCLAALPSVLTPAMREQVASVLPFEPVTLGLDLRGGSHLVLEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
DGAGLQKARLNSLLDDTRRVLRGERVSASSARISGNGVTVSIPDAQDRDKVLPKLQELAT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHC
PVSTVGFAASAPEVEVSTTGDVITLGMTEAGLADRMTKAVEQSLEIIRNRVDQVGVAEPL
CHHHHCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IQRIGSNRILVQLPGLQDPTRLRELLGSTAQMSFHMLDQSVDVTQPAPRGVDILPGADDG
HHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCC
NRYAVETRIAISGERLEDAKVGFDQRTNQPVVDFTFDSLGARQFADITRENVGRPFAIVL
CEEEEEEEEEECCCCCCHHHCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHCCCCEEEEE
DGKVLTAPVINEPILGGRGQISGSFTVEEATVLSALLRSGALPAPLTIIEERSVGPNLGS
CCCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
DSIRMGLFTGLAGFGLVVVLMVVLYGAWGMIANVGLVLHTIMTIGILGLIGSTLTLPGIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIILGIGMAVDANILINARIREETEAGAGAMKALDIGFNKAYATIIDSNVTTLAGTVLLF
HHHHHHHHHCCCEEEEEEEECHHHHCCCCHHHHEECCCCCEEEEEECCCHHHHHHHHHHE
WFGSGPVKGFAVTMMLGIGISMFTSVTVVRLLMREVVVRRKMKKLVIPSLFGPVPRLPSF
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SFMKGRFLAIGFSAFLSISSVVLFFTPGLNYGIDFIGGIQVEAVSKEKIDLATLRRSVEE
HHHCCCHHEEHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LNLGEVALQDFGGGQSVLIRVQRQPGGEQAQSLALNKVKDAVTTAIPGASMERTEVVGPT
CCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCC
VSGELARSGFLAVALAMVAILLYIWFRFEWHFAVGAIAVLLLDITKTVGFFALTGIDFNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCH
TAIAALLTMIGYSVNDKVVVYDRMRENLRRYKSMAFSDLIDLSINQVIARCIFTSAATAL
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVPMAIWGGEAVQSFAWPMIFGVIVATTSSIYIGGPILLFLSRWWKEREAARSGGQQAE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCC
TPTA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9826342 [H]