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The map label for this gene is frk [H]

Identifier: 150395336

GI number: 150395336

Start: 118915

End: 119847

Strand: Direct

Name: frk [H]

Synonym: Smed_0108

Alternate gene names: 150395336

Gene position: 118915-119847 (Clockwise)

Preceding gene: 150395335

Following gene: 150395339

Centisome position: 3.14

GC content: 63.02

Gene sequence:

>933_bases
ATGGTCATGATCGTTTGCTGCGGAGAGGCCCTGATCGACATGCTGCCGCGGGAGACGACGGCGGGCGAGAGCGCCTTTGC
GCCCTATGCGGGCGGCGCGATCTTCAACACGGCCATCGCGCTTGGCCGGCTCGGCGTCCCCACCGGCTTTTTCACCGGCC
TTTCGGACGATATGTTCGGCGACATCCTGCGCGCGACGCTCAAGGCCGCGAATGTCGATTTCGCTCCCTGCGCGACGCTG
CCGCTGCACACGACGCTCGCCTTCGTGAAACTCGTCAACGGGCACGCAAGCTATGCCTTTTTCGATGAGAACACGGCGGG
GCGGATGATAACGACCGAGCACCTTCCGGCGCTCGGCGATTTCTGCGAGGCGCTGCATTTCGGTGCGATCAGCCTCATTC
CCGAGCCATGCGGCTCCACTTACGAGGCGCTGATGGCGCGGGAACACGAAAAGCGCGTAATCTCCTTCGATCCCAATATC
CGGCCCGGCTTCATCAAGGACCGAAACGCGCATGTCGCCCGCATGAACCGCATGGCGGCCATGTCGGATATCGTCAAGTT
CTCCGACGAAGATCTCGCCTGGTTCGGAATGGAGGGCGACCATGACGCACTCGCAGCCGAATGGCTCAAGCGTGGCCCGA
AGCTGGTGCTGATCACCCGGGGCGCCGATGGTGCCGTGGGTTACACGAACGACCATAAGGTCGAAGTCGAAAGCGAGCGC
GTCGAGGTCGTCGACACGGTCGGCGCGGGTGACACTTTCGATGCCGGCGTTCTGGCCTCGCTGAAGTTCGGTAACCTGCT
GACCAAGGAAAATATAGCAGGCTTGAGGGACGAGGACATTTACCGGGCTGTGGCGCTCGGAGCGAAAGCTGCGGCGGTCA
CCGTCTCGCGCGCGGGCGCCAACCCGCCGTGGCGACACGAACTCGGACTTTAA

Upstream 100 bases:

>100_bases
CGCTTGCCTGGTCTGCGAAGAATGGCGGCGTCGGCGCACTCGCGGACCGGTAACGGGGTGCGCGCAATTTTTCGATTCGT
TTGAAAATGTCTGGGGAGGA

Downstream 100 bases:

>100_bases
TTCCGCGCGCGCCGCCGACGCGAGGCTGCTGGATTCCTGTGACAAGCACGGGAATGATGGGGAGAAGGAAATGTTGAGGC
GCCGACTGGAACAGCGCCTC

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVMIVCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAIALGRLGVPTGFFTGLSDDMFGDILRATLKAANVDFAPCATL
PLHTTLAFVKLVNGHASYAFFDENTAGRMITTEHLPALGDFCEALHFGAISLIPEPCGSTYEALMAREHEKRVISFDPNI
RPGFIKDRNAHVARMNRMAAMSDIVKFSDEDLAWFGMEGDHDALAAEWLKRGPKLVLITRGADGAVGYTNDHKVEVESER
VEVVDTVGAGDTFDAGVLASLKFGNLLTKENIAGLRDEDIYRAVALGAKAAAVTVSRAGANPPWRHELGL

Sequences:

>Translated_310_residues
MVMIVCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAIALGRLGVPTGFFTGLSDDMFGDILRATLKAANVDFAPCATL
PLHTTLAFVKLVNGHASYAFFDENTAGRMITTEHLPALGDFCEALHFGAISLIPEPCGSTYEALMAREHEKRVISFDPNI
RPGFIKDRNAHVARMNRMAAMSDIVKFSDEDLAWFGMEGDHDALAAEWLKRGPKLVLITRGADGAVGYTNDHKVEVESER
VEVVDTVGAGDTFDAGVLASLKFGNLLTKENIAGLRDEDIYRAVALGAKAAAVTVSRAGANPPWRHELGL
>Mature_310_residues
MVMIVCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAIALGRLGVPTGFFTGLSDDMFGDILRATLKAANVDFAPCATL
PLHTTLAFVKLVNGHASYAFFDENTAGRMITTEHLPALGDFCEALHFGAISLIPEPCGSTYEALMAREHEKRVISFDPNI
RPGFIKDRNAHVARMNRMAAMSDIVKFSDEDLAWFGMEGDHDALAAEWLKRGPKLVLITRGADGAVGYTNDHKVEVESER
VEVVDTVGAGDTFDAGVLASLKFGNLLTKENIAGLRDEDIYRAVALGAKAAAVTVSRAGANPPWRHELGL

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1790193, Length=305, Percent_Identity=26.8852459016393, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 33260; Mature: 33260

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMIVCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAIALGRLGVPTGFFTGLSDDMFG
CEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHH
DILRATLKAANVDFAPCATLPLHTTLAFVKLVNGHASYAFFDENTAGRMITTEHLPALGD
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHCCCHHHH
FCEALHFGAISLIPEPCGSTYEALMAREHEKRVISFDPNIRPGFIKDRNAHVARMNRMAA
HHHHHHCCHHEECCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
MSDIVKFSDEDLAWFGMEGDHDALAAEWLKRGPKLVLITRGADGAVGYTNDHKVEVESER
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCC
VEVVDTVGAGDTFDAGVLASLKFGNLLTKENIAGLRDEDIYRAVALGAKAAAVTVSRAGA
EEEEEECCCCCCCCCHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCCHHEEEEECCCC
NPPWRHELGL
CCCCCCCCCC
>Mature Secondary Structure
MVMIVCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAIALGRLGVPTGFFTGLSDDMFG
CEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHH
DILRATLKAANVDFAPCATLPLHTTLAFVKLVNGHASYAFFDENTAGRMITTEHLPALGD
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHCCCHHHH
FCEALHFGAISLIPEPCGSTYEALMAREHEKRVISFDPNIRPGFIKDRNAHVARMNRMAA
HHHHHHCCHHEECCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
MSDIVKFSDEDLAWFGMEGDHDALAAEWLKRGPKLVLITRGADGAVGYTNDHKVEVESER
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEECCCC
VEVVDTVGAGDTFDAGVLASLKFGNLLTKENIAGLRDEDIYRAVALGAKAAAVTVSRAGA
EEEEEECCCCCCCCCHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCCHHEEEEECCCC
NPPWRHELGL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8932706 [H]