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The map label for this gene is cpnA [H]

Identifier: 150395089

GI number: 150395089

Start: 2753663

End: 2754367

Strand: Direct

Name: cpnA [H]

Synonym: SaurJH1_2655

Alternate gene names: 150395089

Gene position: 2753663-2754367 (Clockwise)

Preceding gene: 150395088

Following gene: 150395090

Centisome position: 94.74

GC content: 38.3

Gene sequence:

>705_bases
ATGACTAAAATTGTGTTAATCACAGGAGGCAATAAAGGGTTAGGCTATGCAAGTGCAGAGGCACTTAAAGCATTGGGTTA
CAAAGTTTATATAGGTTCTCGGAATGATGTAAGAGGACAACAAGCATCACAAAAATTAGGTGTTCATTATGTACAGTTAG
ATGTTACAAGTGACTACTCAGTCAAAAATGCTTATAACATGATTGCTGAAAAAGAAGGCCGTCTTGATATCCTCATTAAC
AATGCAGGTATATCTGGTCAATTTTCAGCACCTTCCAAATTGCCACCTCGTGACGTTGAAGAAGTATATCAAACGAATGT
ATTCGGTATCGTACGAATGATGAATACATTCGTCCCTCTCTTAGAAAAATCTGAACAACCTGTTGTCGTCAACGTATCAA
GTGGTTTAGGTTCATTTGGAATGGTTACAAACCCCGAAACAGCTGAATCTAAAGTGAATTCATTAGCTTATTGTTCGTCT
AAATCGGCAGTAACAATGCTAACGCTACAATACGCTAAAGGATTACCTAACATGCAAATCAATGCTGCTGACCCAGGCGC
TACAAATACTGATTTAGTTGGTGATTTTAGTAATAATTCCAAACACGTTTCTGAAGGAATCAAGCCAATCATTCAATTAG
CAACGATTGGTGCAGATGGCCCAACAGGTACATTTATTAATGGCGATGGAGAAATGCCTTGGTAG

Upstream 100 bases:

>100_bases
TCAACTAGTGTATTTGCCTTCCAAATAGAGCATCGCCATATTTCAATTGAAGCGTACAGAAATTATTTATTAAACATTTA
TTTAGATGAGGTGGAACGTA

Downstream 100 bases:

>100_bases
ATCAATTTTATGTTACAAACATTGAAATTAGAGGTATATAAAAAATGCTTCTGCAATAGATGCAATATACATGCAAAACA
ATATGGAGGCGAATTAAATG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILIN
NAGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSS
KSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW

Sequences:

>Translated_234_residues
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILIN
NAGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSS
KSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
>Mature_233_residues
TKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINN
AGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSK
SAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW

Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4502599, Length=276, Percent_Identity=28.2608695652174, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI10190746, Length=237, Percent_Identity=31.2236286919831, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4504503, Length=205, Percent_Identity=34.1463414634146, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI186928839, Length=202, Percent_Identity=29.7029702970297, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI193804850, Length=207, Percent_Identity=28.0193236714976, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI225579078, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787820, Length=138, Percent_Identity=28.2608695652174, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=223, Percent_Identity=28.2511210762332, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=211, Percent_Identity=29.8578199052133, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17505416, Length=150, Percent_Identity=34, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193207563, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558994, Length=212, Percent_Identity=31.1320754716981, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=26.7326732673267, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28571387, Length=208, Percent_Identity=27.4038461538462, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45554248, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640117, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573296, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076371, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=28.6407766990291, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24586328, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=29.7029702970297, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641232, Length=204, Percent_Identity=30.8823529411765, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.163 [H]

Molecular weight: Translated: 24928; Mature: 24796

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYS
CEEEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCEEEEEEEECCCCC
VKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTFVPL
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQI
HCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEHHHCCCCCCEE
NAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
ECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCEECCCCCCCC
>Mature Secondary Structure 
TKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYS
EEEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCEEEEEEEECCCCC
VKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLPPRDVEEVYQTNVFGIVRMMNTFVPL
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQI
HCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEHHHCCCCCCEE
NAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
ECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12406764 [H]