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The map label for this gene is luxS

Identifier: 150394649

GI number: 150394649

Start: 2292682

End: 2293152

Strand: Direct

Name: luxS

Synonym: SaurJH1_2208

Alternate gene names: 150394649

Gene position: 2292682-2293152 (Clockwise)

Preceding gene: 150394645

Following gene: 150394653

Centisome position: 78.88

GC content: 33.97

Gene sequence:

>471_bases
ATGACAAAAATGAATGTTGAAAGTTTCAATTTAGATCATACTAAAGTGGTTGCCCCATTTATTAGATTAGCGGGAACGAT
GGAAGGATTAAACGGAGATGTCATTCACAAATACGACATTCGTTTCAAACAACCAAACAAAGAACATATGGATATGCCAG
GACTACATTCATTAGAACATTTAATGGCTGAAAATATTAGAAATCATAGTGACAAAGTTGTTGATTTAAGTCCTATGGGT
TGCCAAACTGGTTTCTATGTATCATTTATTAATCATGATAATTATGATGATGTATTAAATATTGTTGAAGCAACTTTAAA
TGATGTGCTAAATGCTACTGAAGTGCCTGCTTGTAATGAAGTACAATGTGGCTGGGCAGCAAGTCATTCATTAGAAGGTG
CTAAAACTATCGCTCAAGCATTTCTAGACAAACGAAACGAATGGCATGATGTTTTCGGTACAGGAAAATAA

Upstream 100 bases:

>100_bases
AGTATTGTTAGAAACACAACTTACAACAAACTTAAGTTTTATATTGCAACAAATCATAAGCGTTTTATAGTTTTGAGTAG
TAAATAGGAGGAAATTCAAA

Downstream 100 bases:

>100_bases
ATCTTAGTCAATCAAGTTAATCAGAAAAGCAGTCGAACAATGATGTTACAATCGCCATTGTCCAACTGCTTTTTATTATG
CTTCAAAGTCAAAAAATCGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Sequences:

>Translated_156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
>Mature_155_residues
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGC
QTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.7808219178082, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_STAA1 (A7X4Y8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442708.1
- ProteinModelPortal:   A7X4Y8
- SMR:   A7X4Y8
- STRING:   A7X4Y8
- EnsemblBacteria:   EBSTAT00000003918
- GeneID:   5559239
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2118
- eggNOG:   COG1854
- GeneTree:   EBGT00050000025271
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   SAUR418127:SAHV_2118-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17514; Mature: 17383

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA