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The map label for this gene is ruvC [H]

Identifier: 150010366

GI number: 150010366

Start: 4632399

End: 4632956

Strand: Direct

Name: ruvC [H]

Synonym: BDI_3803

Alternate gene names: 150010366

Gene position: 4632399-4632956 (Clockwise)

Preceding gene: 150010365

Following gene: 150010368

Centisome position: 96.28

GC content: 48.92

Gene sequence:

>558_bases
ATGATCAAGGACCGTATTATATTAGGCATAGACCCCGGTACGATCGTGATGGGATACGGAATCTTGAAGATCGAGGGGAA
TAAACCGAAGCTGGAAGCTATGGGAATCCTGCAATTGAATAAATATGAGGATCATTATCTCCGTCTGCGTAAGATATTCG
AACGGGTCTTGGCCTTGATCGATCAATACCATCCGGATGAGTTGGCTATCGAGGCGCCTTTCTTCGGGAAGAACGTACAG
AGTATGTTGAAACTCGGAAGGGCACAAGGAGTAGCGATGGCGGCGGCTTTAGAGCGGGATGTCCCGATCTTCGAGTACGC
CCCTCTAAAAATCAAGCTCTCGATCACGGGGAATGGAAATGCGGCGAAAGAACAAGTGGCCGGCATGCTACAACGCTATC
TGAAGATACCGGATGAGTCTATGCTTCCGCAATTGGACGCTACGGATGGGTTGGCGGCGGCTGTTTGTCATTATTTCCAA
ACCAATAATCCGATCTCGGAAAAGAAGTATACGGGATGGAAGGATTTTATCGCTAAGAACCCCGGGAAAGTCCGCTGA

Upstream 100 bases:

>100_bases
TGCGTAAGGAAGGCGGAGCCTTGCAGCAAGATTTGATAGGACGTTATAAAGAGAAGATCGCTGGATTCTCTACCCTGTTG
GAAGATATAGAGCTACCTAA

Downstream 100 bases:

>100_bases
TATGAGCTTAAAAAACATAGTTATGAAATTCTCAAACCATAACTAAGGTTCAAAGAATTCATAACTATGTTTTTATTTAG
CCTAAACTGACCTTATTCTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYEDHYLRLRKIFERVLALIDQYHPDELAIEAPFFGKNVQ
SMLKLGRAQGVAMAAALERDVPIFEYAPLKIKLSITGNGNAAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQ
TNNPISEKKYTGWKDFIAKNPGKVR

Sequences:

>Translated_185_residues
MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYEDHYLRLRKIFERVLALIDQYHPDELAIEAPFFGKNVQ
SMLKLGRAQGVAMAAALERDVPIFEYAPLKIKLSITGNGNAAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQ
TNNPISEKKYTGWKDFIAKNPGKVR
>Mature_185_residues
MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYEDHYLRLRKIFERVLALIDQYHPDELAIEAPFFGKNVQ
SMLKLGRAQGVAMAAALERDVPIFEYAPLKIKLSITGNGNAAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQ
TNNPISEKKYTGWKDFIAKNPGKVR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=166, Percent_Identity=42.1686746987952, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 20704; Mature: 20704

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYEDHYLRLRKIFERVLALI
CCCCCEEEEECCCEEEEEEEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
DQYHPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALERDVPIFEYAPLKIKLSITGNGN
HCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCEEEEEEEECCCC
AAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQTNNPISEKKYTGWKDFIAKN
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
PGKVR
CCCCC
>Mature Secondary Structure
MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYEDHYLRLRKIFERVLALI
CCCCCEEEEECCCEEEEEEEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
DQYHPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALERDVPIFEYAPLKIKLSITGNGN
HCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCEEEEEEEECCCC
AAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQTNNPISEKKYTGWKDFIAKN
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCC
PGKVR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA