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The map label for this gene is asnC

Identifier: 150010294

GI number: 150010294

Start: 4545720

End: 4547126

Strand: Direct

Name: asnC

Synonym: BDI_3727

Alternate gene names: 150010294

Gene position: 4545720-4547126 (Clockwise)

Preceding gene: 150010293

Following gene: 150010296

Centisome position: 94.48

GC content: 46.06

Gene sequence:

>1407_bases
ATGGAAACAATTAAACGAACAAAAATTGTAGACGTACTGAAAAGCGACGCTTTCGGTACTACCGTGAACGTGAAAGGATG
GGTTCGCACCCGCCGTGGTAGCAAACAGGTGAATTTTATCGCCTTGAATGACGGTTCTACAATCAATAATGTTCAGATCG
TTGTGGATGTAGATAAATTGGGTGATGAGTTCTTGAAACCGATTACCACGGGAGCTAGTATCAGCGTAAACGGTATCTTG
ACACAATCCCAAGGCAAGGGGCAAAGCGTGGAGATACAGGCTACCGAGATTGAGATCTTCGGTACGGCTGATCCAGCTAC
TTATCCGTTGCAGAAAAAGGGACACTCCATGGAGTTTTTACGTGAGATCGCTCACTTGCGTCCTCGTACGAATACATTTG
GCGCGGTATTCCGTATTCGTCACAATATGGCTTACGCTATCCATAAGTTTTTCCATGATAGAGGCTTTTTCTATTTCCAT
ACGCCGATCATCACGGCTTCCGACTGTGAGGGTGCCGGACAGATGTTCCAAGTTACTACCAAAAATTTGTACGACTTGAA
AAAGGATGAGAATGGCTCTATCATTTATGAGGACGATTTCTTCGGCAAGCAGGCTAGCTTGACGGTTTCCGGACAGTTGG
AGGGTGAGTTGGCAGCTACAGCCTTGGGACAGATTTATACGTTTGGCCCTACGTTCCGCGCTGAGAACTCAAATACGCCT
CGTCATTTGGCGGAATTCTGGATGATTGAGCCGGAAGTCGCTTTTAATGATATCACGGACAATATGGAGTTGGCCGAGGA
GTTCATTAAATATTGCGTACAATGGGCGTTGGATAACTGTATGGAGGATATCAAGTTCTTGAACGATATGTTCGATAAGG
AATTGATCGCTCGTCTGGAAGGGGTCTTGAAAGACTCATTCGTTCGCTTGCCGTACACTGAAGGAATCAAGATATTGGAA
GAGGCTGTCGCTAAAGGACATAAATTTGAGTTCCCTGTTTATTGGGGTGTAGACTTGGCTTCTGAGCATGAACGTTTCTT
GGTGGAGGATCACTTCAAACGTCCGGTAATTTTAACGGATTACCCGAAAGAGATCAAGGCTTTCTATATGAAGCAAAACG
AGGATGGAAAGACGGTGCGTGCCATGGACGTATTGTTCCCGAAGATCGGAGAGATCATCGGCGGTTCCGAGCGTGAGGCC
GACTATGATAAGCTAATGACTCGTATTGATGAGTTGGGCATCCCGATGAAGGATATGTGGTGGTACTTAGATACTCGCCG
TTTTGGTACGGTGCCTCACTCTGGTTTCGGTTTGGGCTTTGAGCGTCTTTTGCTGTTTGTTACAGGCATGGCAAATATAC
GTGACGTGATACCTTTCCCGCGTACACCGAATAATGCTGAGTTCTAA

Upstream 100 bases:

>100_bases
TGACTAAGAAGAACTTAGGCCGCGGTAAATGGCGTTACTTAAATGAAAGGGAAGTGAACGCTCTTAGGATGGGAGCTTTC
GAATAAAAAAAACGATACAG

Downstream 100 bases:

>100_bases
TAGTGCTTAGTGATCATGATAAAAAGGGCCCGTAACCGGTTTCAACCGAATTACGGACCCTTTTCTTATATTAGCTTCCT
TTATTAATCGTCGTCCAGAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
METIKRTKIVDVLKSDAFGTTVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDVDKLGDEFLKPITTGASISVNGIL
TQSQGKGQSVEIQATEIEIFGTADPATYPLQKKGHSMEFLREIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFH
TPIITASDCEGAGQMFQVTTKNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELAATALGQIYTFGPTFRAENSNTP
RHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWALDNCMEDIKFLNDMFDKELIARLEGVLKDSFVRLPYTEGIKILE
EAVAKGHKFEFPVYWGVDLASEHERFLVEDHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREA
DYDKLMTRIDELGIPMKDMWWYLDTRRFGTVPHSGFGLGFERLLLFVTGMANIRDVIPFPRTPNNAEF

Sequences:

>Translated_468_residues
METIKRTKIVDVLKSDAFGTTVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDVDKLGDEFLKPITTGASISVNGIL
TQSQGKGQSVEIQATEIEIFGTADPATYPLQKKGHSMEFLREIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFH
TPIITASDCEGAGQMFQVTTKNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELAATALGQIYTFGPTFRAENSNTP
RHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWALDNCMEDIKFLNDMFDKELIARLEGVLKDSFVRLPYTEGIKILE
EAVAKGHKFEFPVYWGVDLASEHERFLVEDHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREA
DYDKLMTRIDELGIPMKDMWWYLDTRRFGTVPHSGFGLGFERLLLFVTGMANIRDVIPFPRTPNNAEF
>Mature_468_residues
METIKRTKIVDVLKSDAFGTTVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDVDKLGDEFLKPITTGASISVNGIL
TQSQGKGQSVEIQATEIEIFGTADPATYPLQKKGHSMEFLREIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFH
TPIITASDCEGAGQMFQVTTKNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELAATALGQIYTFGPTFRAENSNTP
RHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWALDNCMEDIKFLNDMFDKELIARLEGVLKDSFVRLPYTEGIKILE
EAVAKGHKFEFPVYWGVDLASEHERFLVEDHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREA
DYDKLMTRIDELGIPMKDMWWYLDTRRFGTVPHSGFGLGFERLLLFVTGMANIRDVIPFPRTPNNAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=456, Percent_Identity=42.7631578947368, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI4758762, Length=454, Percent_Identity=29.9559471365639, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI45439306, Length=494, Percent_Identity=27.5303643724696, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1787161, Length=465, Percent_Identity=55.6989247311828, Blast_Score=534, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=31.7016317016317, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=30.5986696230599, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=504, Percent_Identity=25.3968253968254, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319872, Length=464, Percent_Identity=36.2068965517241, Blast_Score=299, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6321807, Length=468, Percent_Identity=30.7692307692308, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323011, Length=507, Percent_Identity=27.0216962524655, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19922416, Length=470, Percent_Identity=35.531914893617, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI19921528, Length=464, Percent_Identity=30.1724137931034, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17136276, Length=477, Percent_Identity=26.2054507337526, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_PARD8 (A6LIA1)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001305037.1
- ProteinModelPortal:   A6LIA1
- SMR:   A6LIA1
- STRING:   A6LIA1
- GeneID:   5308876
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_3727
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   PDIS435591:BDI_3727-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 53354; Mature: 53354

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIKRTKIVDVLKSDAFGTTVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDVDKL
CCCHHHHHHHHHHHCCCCCCEEEEEHEEEECCCCCEEEEEEECCCCCCCCEEEEEEHHHH
GDEFLKPITTGASISVNGILTQSQGKGQSVEIQATEIEIFGTADPATYPLQKKGHSMEFL
CHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCHHHCCCHHHHH
REIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFHTPIITASDCEGAGQMFQVTT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEEH
KNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELAATALGQIYTFGPTFRAENSNTP
HHHHHCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHEECCCEEECCCCCCH
RHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWALDNCMEDIKFLNDMFDKELIARLE
HHHHHHHEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLKDSFVRLPYTEGIKILEEAVAKGHKFEFPVYWGVDLASEHERFLVEDHFKRPVILTD
HHHHHCEEECCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEC
YPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREADYDKLMTRIDELGIPMKDMW
CCHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
WYLDTRRFGTVPHSGFGLGFERLLLFVTGMANIRDVIPFPRTPNNAEF
EEEECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
METIKRTKIVDVLKSDAFGTTVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDVDKL
CCCHHHHHHHHHHHCCCCCCEEEEEHEEEECCCCCEEEEEEECCCCCCCCEEEEEEHHHH
GDEFLKPITTGASISVNGILTQSQGKGQSVEIQATEIEIFGTADPATYPLQKKGHSMEFL
CHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCHHHCCCHHHHH
REIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFHTPIITASDCEGAGQMFQVTT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEEH
KNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELAATALGQIYTFGPTFRAENSNTP
HHHHHCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHEECCCEEECCCCCCH
RHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWALDNCMEDIKFLNDMFDKELIARLE
HHHHHHHEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLKDSFVRLPYTEGIKILEEAVAKGHKFEFPVYWGVDLASEHERFLVEDHFKRPVILTD
HHHHHCEEECCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEC
YPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREADYDKLMTRIDELGIPMKDMW
CCHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
WYLDTRRFGTVPHSGFGLGFERLLLFVTGMANIRDVIPFPRTPNNAEF
EEEECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA