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The map label for this gene is ribD [H]

Identifier: 150010266

GI number: 150010266

Start: 4512964

End: 4514043

Strand: Direct

Name: ribD [H]

Synonym: BDI_3695

Alternate gene names: 150010266

Gene position: 4512964-4514043 (Clockwise)

Preceding gene: 150010256

Following gene: 150010267

Centisome position: 93.8

GC content: 50.37

Gene sequence:

>1080_bases
ATGGTAGAGGTTGAAGAGAAATACATGGCTCGTTGCATCGAGTTGGCTAAAGGAGGGAGGGGAAATGTCAGTCCGAATCC
GATGGTTGGTGCGGTGGTTGTGCATAAGGGCCGTATTATCGGTGAGGGATTTCACAGGAAATGCGGGGAGGCGCATGCCG
AGGTGAATGCTATCGCTTCCGTGAAAGACGAGTCTTTGTTGAAAGACAGTACGATTTATGTGAGTCTGGAGCCTTGCTCT
CATTATGGGAAAACGCCTCCTTGCGCCGAGTTGATTATCAGGAAAGGGATTCCACGGGTGGTGGTCGGTTGCTTGGATCC
TTTTCCCGAGGTGTCGGGGCGAGGTGTGCGGATGTTGCGTGAGGCCGGTGTCGAGGTAGTCACAGGCGTGATGGAGGAAG
AAGCCCGTGCGTTGAACAAGGCGTTTATGACGCTACAAACGAAAGGCCGTCCTTATATTATCTTGAAATGGGCGCAGAGT
GAGGATGGGTTTATCGACCGTTTACGTATGGACGTGTCGGAGCCGGTCACGGTTTTGTCTTCTCCGGAGACTTCCCGCTT
GGTGCATAAACTTCGCTCGGAGGTGGCGGCTATCATGGTCGGTACACGGACTGCTTTATTGGACAATCCATCATTGAACG
TGCGCCATTGGTCCGGTAATTCTCCGGTTAGGGTCGTATTGGATCGTCGGCTCGTTATTCCCGATTCTTATCGGTTGCTG
AATGGTTCCTCACGTACATTAATATTTACGGAGAAGGAAGTGGAAAACCGAGAGAACGTGGAGTATATCCGGATAGATTT
CGAGGGTCCGGTGATCCGGCAAGTGCTAGATCATCTTGCTGTCCGGAAGTTGGATTCCTTATTGGTGGAAGGTGGGACTC
AGCTGATTAATTCTTTTGTGGAAGCGGATGTATGGGACGAGGCGAGGGTGGAAACGGCCCCGGTTCGTCTGTATCAAGGG
GTGCATACGCCGATGCTTGGAAAGGAGGCTGTTAGCGGCATCTCCGGACGTTCTGTTATGAGCATTAAAAATCATAACTA
TGAAATTTTAAATCATAACGATGAGTTCGAAAAATCATAA

Upstream 100 bases:

>100_bases
ATATCTTTGAGGGAATTTCGGATGTAAGCGACGGTCTCAGTCATATCTTTCTCTTGTTTTATCGCGAAAGTAGTGTAAAA
ACCGTTTATATGCAAAGATT

Downstream 100 bases:

>100_bases
CTATGAATTTTAAGGCTCATATAATCAACTAAAATATTATAAATATTAGCAGGTATTAGGGTGAAAGCAAAAAATGTTTC
TACTTTTGTGCCTTTATATG

Product: riboflavin biosynthesis protein ribD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MVEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGFHRKCGEAHAEVNAIASVKDESLLKDSTIYVSLEPCS
HYGKTPPCAELIIRKGIPRVVVGCLDPFPEVSGRGVRMLREAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQS
EDGFIDRLRMDVSEPVTVLSSPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWSGNSPVRVVLDRRLVIPDSYRLL
NGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVLDHLAVRKLDSLLVEGGTQLINSFVEADVWDEARVETAPVRLYQG
VHTPMLGKEAVSGISGRSVMSIKNHNYEILNHNDEFEKS

Sequences:

>Translated_359_residues
MVEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGFHRKCGEAHAEVNAIASVKDESLLKDSTIYVSLEPCS
HYGKTPPCAELIIRKGIPRVVVGCLDPFPEVSGRGVRMLREAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQS
EDGFIDRLRMDVSEPVTVLSSPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWSGNSPVRVVLDRRLVIPDSYRLL
NGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVLDHLAVRKLDSLLVEGGTQLINSFVEADVWDEARVETAPVRLYQG
VHTPMLGKEAVSGISGRSVMSIKNHNYEILNHNDEFEKS
>Mature_359_residues
MVEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGFHRKCGEAHAEVNAIASVKDESLLKDSTIYVSLEPCS
HYGKTPPCAELIIRKGIPRVVVGCLDPFPEVSGRGVRMLREAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQS
EDGFIDRLRMDVSEPVTVLSSPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWSGNSPVRVVLDRRLVIPDSYRLL
NGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVLDHLAVRKLDSLLVEGGTQLINSFVEADVWDEARVETAPVRLYQG
VHTPMLGKEAVSGISGRSVMSIKNHNYEILNHNDEFEKS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=329, Percent_Identity=37.3860182370821, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=35.1851851851852, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39946; Mature: 39946

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGFHRKCGEAHAEVNAIAS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEECCHHHHHHHHHHHHHHHHHH
VKDESLLKDSTIYVSLEPCSHYGKTPPCAELIIRKGIPRVVVGCLDPFPEVSGRGVRMLR
CCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHH
EAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQSEDGFIDRLRMDVSEPVTVLS
HCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEC
SPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWSGNSPVRVVLDRRLVIPDSYRLL
CCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCEEEEEECEEECCCCCEEE
NGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVLDHLAVRKLDSLLVEGGTQLINSFV
CCCCCEEEEECHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EADVWDEARVETAPVRLYQGVHTPMLGKEAVSGISGRSVMSIKNHNYEILNHNDEFEKS
HCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEECCCCCCCCC
>Mature Secondary Structure
MVEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGFHRKCGEAHAEVNAIAS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEECCHHHHHHHHHHHHHHHHHH
VKDESLLKDSTIYVSLEPCSHYGKTPPCAELIIRKGIPRVVVGCLDPFPEVSGRGVRMLR
CCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHH
EAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQSEDGFIDRLRMDVSEPVTVLS
HCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEC
SPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWSGNSPVRVVLDRRLVIPDSYRLL
CCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCEEEEEECEEECCCCCEEE
NGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVLDHLAVRKLDSLLVEGGTQLINSFV
CCCCCEEEEECHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EADVWDEARVETAPVRLYQGVHTPMLGKEAVSGISGRSVMSIKNHNYEILNHNDEFEKS
HCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]