Click here to switch to the map view.

The map label for this gene is hutH [H]

Identifier: 150010225

GI number: 150010225

Start: 4457297

End: 4458793

Strand: Direct

Name: hutH [H]

Synonym: BDI_3648

Alternate gene names: 150010225

Gene position: 4457297-4458793 (Clockwise)

Preceding gene: 150010224

Following gene: 150010226

Centisome position: 92.64

GC content: 48.1

Gene sequence:

>1497_bases
ATGAGTAATGTTTATTATGTGGGTTCCGAGCCTCTCTCTTTTGAGGGAATCGAACGGATACTTACTCAAAATATGAAGTT
GGAGCTTTCACCCGAGGTGAAGGAGCGCATCCAGCGTTGCCGGGATTACTTGGATCATAAGATCGAGCAACAGGAGGGGC
CTTTGTATGGGATTACTACCGGTTTCGGGTCCTTATGTAATAAGAATATCTCTCCGGACGAATTGAGCACCTTGCAAGAG
AACTTGGTGAAAAGTCATGCCTGTAGCGTAGGGGATGAGGTAAGTCCGGTGATCGTTCGTTTGATGATGTTATTGAAAGC
GCATGCCCTTTCGTTGGGGCATAGTGGCGTACAGGTGATCACCGTACAACGTATTCTGGATTTTTTCAATAATGACGTGC
TTCCGATCGTGTATGATCGTGGCTCTTTAGGCGCTTCCGGTGATTTGGCGCCTCTGGCGAATTTGTTCCTGCCTCTGATC
GGCGTGGGTGACGTTTATTATAAGGGCCGCAAACGGGAAGCAATCAGCGTATTGGACGAGTTCGCTTGGAAGCCTGTGAA
GCTGAAAAGCAAGGAGGGGTTAGCTTTATTGAACGGTACGCAATTTATGAGCGCCAATGGCGTATTCGCCTTGATGCGTG
CGTTTAGCCTGTCCAAGAAAGCGGATCTGATCGCCGCTTTATCCTTGGAGGCTTTCGATGGGCGTATCGATCCTTTCATG
GATTGTATCCAGCAGATGCGTCCGCATCCCGGACAAATCGAGACCGGGGCCGCTTTTCGACGGTTATTGGAGGGAAGTGA
GTTAATCGCCCGGAAAAAGGAACATGTTCAGGACCCGTATTCATTCCGTTGTATCCCTCAAGTGCATGGGGCTACGAAAG
ACGCTATCAATTATGTGGCGAATGTCCTGCTTACCGAAGTAAATTCCGTGACGGATAACCCGACGATCTTCCCGAAGGAG
GATAAGATTATTTCCGGCGGTAATTTCCACGGTCAGCCCTTGGCGATTTCTTATGATTTCTTGGCGATTGCCTTGGCTGA
GTTAGGAAATATATCGGAACGTCGTGTCGCTCAATTGATCATGGGTTTGCGGGGATTGCCTGAGTTCTTGGTCGCTAATC
CCGGCCTAAACTCCGGTTTCATGATCCCTCAATATGCGGCTGCTAGTATGGTAAGCCAGAATAAGATGTATTGCTATGCG
GCGAGCAGCGATTCTATCGTGTCCAGTAATGGGCAAGAGGATCATGTGAGTATGGGGGCGAATGCGGCGACGAAGTTGTT
TAAGATCATGGACAATTTGGATCATATCTTGGCGATCGAGTTGATGAATGCGGCACAAGGAATTGAGTTCCGTCGTCCGG
CTAGGACTTCTCCGGTATTAGAGAAGTTCTTGAAGGATTACCGGAAAGAGGTGCCATTTATCGATGAGGATATTATTATG
TACACGGAAATACATCGTACGGTGGCGTTTATCCGTAGGAAAGACTTTGTATATTAA

Upstream 100 bases:

>100_bases
GTTCGTCGGAATGATGCGGAAGAAAGCGGATGAACTGGAGGCGAACGCTATCCGTGTAGAGCAAAAGTTATTGGATTGGG
TGAAGACTAAATTATAGCAT

Downstream 100 bases:

>100_bases
TGAATATCGTTAATAGAGGTTAGAAATCCAGCTGAATTTCCTATTCGGCTGGATTATTTTGTATTTTCGCCGTCAATCTA
AACACAATCGATCTACTTTA

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYLDHKIEQQEGPLYGITTGFGSLCNKNISPDELSTLQE
NLVKSHACSVGDEVSPVIVRLMMLLKAHALSLGHSGVQVITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLI
GVGDVYYKGRKREAISVLDEFAWKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKADLIAALSLEAFDGRIDPFM
DCIQQMRPHPGQIETGAAFRRLLEGSELIARKKEHVQDPYSFRCIPQVHGATKDAINYVANVLLTEVNSVTDNPTIFPKE
DKIISGGNFHGQPLAISYDFLAIALAELGNISERRVAQLIMGLRGLPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYA
ASSDSIVSSNGQEDHVSMGANAATKLFKIMDNLDHILAIELMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIM
YTEIHRTVAFIRRKDFVY

Sequences:

>Translated_498_residues
MSNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYLDHKIEQQEGPLYGITTGFGSLCNKNISPDELSTLQE
NLVKSHACSVGDEVSPVIVRLMMLLKAHALSLGHSGVQVITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLI
GVGDVYYKGRKREAISVLDEFAWKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKADLIAALSLEAFDGRIDPFM
DCIQQMRPHPGQIETGAAFRRLLEGSELIARKKEHVQDPYSFRCIPQVHGATKDAINYVANVLLTEVNSVTDNPTIFPKE
DKIISGGNFHGQPLAISYDFLAIALAELGNISERRVAQLIMGLRGLPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYA
ASSDSIVSSNGQEDHVSMGANAATKLFKIMDNLDHILAIELMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIM
YTEIHRTVAFIRRKDFVY
>Mature_497_residues
SNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYLDHKIEQQEGPLYGITTGFGSLCNKNISPDELSTLQEN
LVKSHACSVGDEVSPVIVRLMMLLKAHALSLGHSGVQVITVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIG
VGDVYYKGRKREAISVLDEFAWKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKADLIAALSLEAFDGRIDPFMD
CIQQMRPHPGQIETGAAFRRLLEGSELIARKKEHVQDPYSFRCIPQVHGATKDAINYVANVLLTEVNSVTDNPTIFPKED
KIISGGNFHGQPLAISYDFLAIALAELGNISERRVAQLIMGLRGLPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYAA
SSDSIVSSNGQEDHVSMGANAATKLFKIMDNLDHILAIELMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIMY
TEIHRTVAFIRRKDFVY

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=460, Percent_Identity=44.1304347826087, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17567831, Length=490, Percent_Identity=41.0204081632653, Blast_Score=351, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 55332; Mature: 55200

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYLDHKIEQQEGPLYGITT
CCCEEEECCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GFGSLCNKNISPDELSTLQENLVKSHACSVGDEVSPVIVRLMMLLKAHALSLGHSGVQVI
CHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
TVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIGVGDVYYKGRKREAISVLDE
EHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHH
FAWKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKADLIAALSLEAFDGRIDPFM
HCCCCEEECCCCCEEEECCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
DCIQQMRPHPGQIETGAAFRRLLEGSELIARKKEHVQDPYSFRCIPQVHGATKDAINYVA
HHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEHHHCCCCHHHHHHHH
NVLLTEVNSVTDNPTIFPKEDKIISGGNFHGQPLAISYDFLAIALAELGNISERRVAQLI
HHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
MGLRGLPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYAASSDSIVSSNGQEDHVSMGA
HHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHCCC
NAATKLFKIMDNLDHILAIELMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
YTEIHRTVAFIRRKDFVY
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYLDHKIEQQEGPLYGITT
CCEEEECCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GFGSLCNKNISPDELSTLQENLVKSHACSVGDEVSPVIVRLMMLLKAHALSLGHSGVQVI
CHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
TVQRILDFFNNDVLPIVYDRGSLGASGDLAPLANLFLPLIGVGDVYYKGRKREAISVLDE
EHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHH
FAWKPVKLKSKEGLALLNGTQFMSANGVFALMRAFSLSKKADLIAALSLEAFDGRIDPFM
HCCCCEEECCCCCEEEECCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
DCIQQMRPHPGQIETGAAFRRLLEGSELIARKKEHVQDPYSFRCIPQVHGATKDAINYVA
HHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEHHHCCCCHHHHHHHH
NVLLTEVNSVTDNPTIFPKEDKIISGGNFHGQPLAISYDFLAIALAELGNISERRVAQLI
HHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
MGLRGLPEFLVANPGLNSGFMIPQYAAASMVSQNKMYCYAASSDSIVSSNGQEDHVSMGA
HHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHCCC
NAATKLFKIMDNLDHILAIELMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
YTEIHRTVAFIRRKDFVY
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA