BacMap

Definition	Parabacteroides distasonis ATCC 8503 chromosome, complete genome.
Accession	NC_009615
Length	4,811,379

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The map label for this gene is fabG [H]

Identifier: 150010207

GI number: 150010207

Start: 4441557

End: 4442291

Strand: Direct

Name: fabG [H]

Synonym: BDI_3630

Alternate gene names: 150010207

Gene position: 4441557-4442291 (Clockwise)

Preceding gene: 150010206

Following gene: 150010208

Centisome position: 92.31

GC content: 42.18

Gene sequence:

>735_bases
TTGGAGAATAAAACGTTTCTGGTGACAGGGGCCTCTTCCGGTATTGGACGTTCTATTGCGGTGGAATGCTCTCGACTAGG
AGCTAGCGTGTATATTACTGCTCGCAATGAGGAACGTCTATGTAAAACCTTATCACAGATGGAAGGTGAAGGACATCAAA
TGATCCTGTCCGATTTATCCGAGGAAGGAGATATTGATCTTTTAGTGAATAAGCTACCTCCGTTGGATGGAGTCGTGCAT
TGTGCGGGAATACAGGAACGAATGTTGTGTAAGATGCTTAAATCTTCGGATATAGAAAACATAATGGCTATTAATTTCAA
TGCACCGATTTTATTGCAACGTACATTGTTGCGAAAGAAAAAAATATCCAAAGGAGCTTCTATTGTTTTTATAGCTTCCC
GTGCGGCTTTTGCTCCAACCGTAGGTAATGCGCTTTATGCCGCTTCAAAAGGTGCGATTTTATCTTATGCCAAGGTACTA
GGTTTGGAGTTGGCGTCACGTCAGATTCGTGTGAATAGTATTTGTCCGGCTATGGTTTGGACGGACTTGACTCGAAAAGA
TGAAACTAAGACGGGGGCTGATTATAATGAAGTTCAAAAATCGTATCCTTTACAGCGGTACGGAAAACCGGAAGATATCG
CTTATTTGGCGGTTTATCTACTTTCGGATACTTCCGTTTGGATGACGGGGTCGGCTATAGATATAACAGGTGGAGGTGAA
TTAACTTTGGTATAA

Upstream 100 bases:

>100_bases
AGATCAAGGCTGATGACCTAAGGAAAGCTGAAACGATAGGTGATTTGTTTGAGATCGTGTGTGCTAAAGGATGAATAGGC
TGAGTTATAATCCTTTTTCT

Downstream 100 bases:

>100_bases
TCATAAGATATGAAGGCATATATAAAACGAATATCATATTATTTGCCCCCAAAGATTCTTTCCAATGAAAAGTTGGTAGA
GGAGTTTCCTGAATGGACAG

Product: 3-oxoacyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MENKTFLVTGASSGIGRSIAVECSRLGASVYITARNEERLCKTLSQMEGEGHQMILSDLSEEGDIDLLVNKLPPLDGVVH
CAGIQERMLCKMLKSSDIENIMAINFNAPILLQRTLLRKKKISKGASIVFIASRAAFAPTVGNALYAASKGAILSYAKVL
GLELASRQIRVNSICPAMVWTDLTRKDETKTGADYNEVQKSYPLQRYGKPEDIAYLAVYLLSDTSVWMTGSAIDITGGGE
LTLV

Sequences:

>Translated_244_residues
MENKTFLVTGASSGIGRSIAVECSRLGASVYITARNEERLCKTLSQMEGEGHQMILSDLSEEGDIDLLVNKLPPLDGVVH
CAGIQERMLCKMLKSSDIENIMAINFNAPILLQRTLLRKKKISKGASIVFIASRAAFAPTVGNALYAASKGAILSYAKVL
GLELASRQIRVNSICPAMVWTDLTRKDETKTGADYNEVQKSYPLQRYGKPEDIAYLAVYLLSDTSVWMTGSAIDITGGGE
LTLV
>Mature_244_residues
MENKTFLVTGASSGIGRSIAVECSRLGASVYITARNEERLCKTLSQMEGEGHQMILSDLSEEGDIDLLVNKLPPLDGVVH
CAGIQERMLCKMLKSSDIENIMAINFNAPILLQRTLLRKKKISKGASIVFIASRAAFAPTVGNALYAASKGAILSYAKVL
GLELASRQIRVNSICPAMVWTDLTRKDETKTGADYNEVQKSYPLQRYGKPEDIAYLAVYLLSDTSVWMTGSAIDITGGGE
LTLV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=29.9180327868852, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=28.1853281853282, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.5546558704453, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=28.6290322580645, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=27.8884462151394, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=31.7708333333333, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=29.9559471365639, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=24.0601503759398, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=26.3374485596708, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=28.2511210762332, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=29.5081967213115, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=29.7959183673469, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=31.2, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=27.6679841897233, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=27.4900398406374, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=28.6792452830189, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=25.4166666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=27.5423728813559, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=25.7028112449799, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=25.2, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=26.4227642276423, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=25.8064516129032, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.8039215686275, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.9595141700405, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.6290322580645, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=30.2583025830258, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=238, Percent_Identity=25.2100840336134, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.9242424242424, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.030303030303, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=280, Percent_Identity=30.3571428571429, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=29.1512915129151, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=29.8892988929889, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.1787072243346, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.9391634980989, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=29.1338582677165, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=29.9242424242424, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.0566037735849, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=29.4339622641509, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=27.4074074074074, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=276, Percent_Identity=26.4492753623188, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=216, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=235, Percent_Identity=28.936170212766, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=26.2948207171315, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=30.327868852459, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=32.3651452282158, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=28.957528957529, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=30, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=28.5140562248996, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=26.9076305220884, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=25.5813953488372, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356301, Length=185, Percent_Identity=27.5675675675676, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=27.8225806451613, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=26.8482490272374, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26496; Mature: 26496

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKTFLVTGASSGIGRSIAVECSRLGASVYITARNEERLCKTLSQMEGEGHQMILSDLS
CCCCEEEEEECCCCCCCHHEEEHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHCC
EEGDIDLLVNKLPPLDGVVHCAGIQERMLCKMLKSSDIENIMAINFNAPILLQRTLLRKK
CCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
KISKGASIVFIASRAAFAPTVGNALYAASKGAILSYAKVLGLELASRQIRVNSICPAMVW
HHCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHH
TDLTRKDETKTGADYNEVQKSYPLQRYGKPEDIAYLAVYLLSDTSVWMTGSAIDITGGGE
HHCCCCCCCCCCCCHHHHHHCCCHHHCCCCCHHHHEEEEEECCCCEEEECCEEEECCCCE
LTLV
EEEC
>Mature Secondary Structure
MENKTFLVTGASSGIGRSIAVECSRLGASVYITARNEERLCKTLSQMEGEGHQMILSDLS
CCCCEEEEEECCCCCCCHHEEEHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHCC
EEGDIDLLVNKLPPLDGVVHCAGIQERMLCKMLKSSDIENIMAINFNAPILLQRTLLRKK
CCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
KISKGASIVFIASRAAFAPTVGNALYAASKGAILSYAKVLGLELASRQIRVNSICPAMVW
HHCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHH
TDLTRKDETKTGADYNEVQKSYPLQRYGKPEDIAYLAVYLLSDTSVWMTGSAIDITGGGE
HHCCCCCCCCCCCCHHHHHHCCCHHHCCCCCHHHHEEEEEECCCCEEEECCEEEECCCCE
LTLV
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]