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The map label for this gene is zraR [H]

Identifier: 150010059

GI number: 150010059

Start: 4254125

End: 4255489

Strand: Direct

Name: zraR [H]

Synonym: BDI_3478

Alternate gene names: 150010059

Gene position: 4254125-4255489 (Clockwise)

Preceding gene: 150010057

Following gene: 150010060

Centisome position: 88.42

GC content: 45.05

Gene sequence:

>1365_bases
ATGAAAAAGGGAAAACTATTAATTATAGATGATAATGAGGACATCCTTTTTGCCCTTAACTTATTACTGGAGCCCTATAT
GGAACAAATAAGAGTGGCTACGCAACCGGAGCGCATCGATCATTTCATGCGGACTTTTATCCCGGATATTATCTTGTTGG
ATATGAATTTCAAACGGGATGCTATTAGTGGTCAGGAGGGTTTCTATTGGCTGGAGAAGATAAAGAAGATAGACCCGGAC
GTGGTGGTTCTTTTTATGACTGCCTATTCGGATACGGATAAGGCCGTGCGGGCGATTAAGGCGGGAGCTACCGACTTTAT
CCCGAAACCTTGGGAAAAGGAGAAATTACTCGCTACACTCTCTTCTGCATTGGAACTTCGGGAGAGTAGGGCGGAAGTGC
GAAATTTAAAGAAACAAGTTGAGATTCTTAGTTCACCCGAGGATGCTGGCTTCGAGATCATCGGTGAAAGCGAACCGATG
CAGGCTATTTTCGCTACGGTCGATAAATTAAAGAATACGGATGCCAATATATTAATCTTGGGGGAGAATGGAACCGGTAA
AGATTTAGTTGCCCGCGCCTTATATCATCAATCTCCGCGTTCGGAGAATCTTTTCGTCGGGATCGATGTGGGCTCTATTC
CGGAACAACTTTTCGAGAGTGAATTATTTGGCTATGAGAAAGGGGCTTTTACGGATGCCCGTAAGGAAAAGCCGGGACGA
ATGGAGGTAGCTTCCGGTGGTACCTTGTTCTTGGATGAGATCGGGAACTTAAGCCTTTCCATGCAAGCGAAACTGTTGAC
CGCTTTGGAAAAACGACAGATAACCCGCTTGGGAGCAACGCAACCCATACCGATTGATATCCGGTTGATCTGCGCAACGA
ACGTGAATATCCATCATCTTGTGGCAGAAGGTACTTTCCGGCAAGATCTTTTATATCGTATTAATACGATCGAGTTACAT
ATTCCTCCCTTGAGGGAACGAGGAAATGACGTGATCTTATTGGCTGAACATTTCTTGTCGAAGTATGCCCGTAAATATAA
GAAAGACTTGAAGGGCATTAACAGGGATGGGAAGAATAAGCTACATAATTATGCTTGGCCCGGTAATGTACGTGAACTGC
AACATGCGATTGAACGGGCGGTTATCTTGTCTGAAAGTAATTGGCTAAGGCCGGAAGACTTTATTCTGCGTTCTGTCCCG
CTTAGGGATAAGGAACCATCCGATGAGTTAAATTTGACGGTATTGGAGAAAGAAGCGATCGAACGTGCCTTACGTCGTGC
CGAGGGGAATATCACTCGTGCCGCCGAGCTTCTAGGGATTACCCGCTTTACCTTGTATCGTAAATTGGAGAAATTTGGCT
TATGA

Upstream 100 bases:

>100_bases
ATTTAACAGTTCATCTGCGCACGGTAATCGTTCGATTACGCACGCTTCTTCCATTGATTTAATACCTACCTTTGAGGCAT
CACAAACTAGTTCAGCGCTT

Downstream 100 bases:

>100_bases
TACGTTACTTGTTGTTCGCTCGTATTTTGGGGATCGTGGTCTTGTCTTTTACTGCCTCATTCTTAATGCTGAAAGGGTTT
TTGTTTATTCCTGCGCTGTT

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMRTFIPDIILLDMNFKRDAISGQEGFYWLEKIKKIDPD
VVVLFMTAYSDTDKAVRAIKAGATDFIPKPWEKEKLLATLSSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPM
QAIFATVDKLKNTDANILILGENGTGKDLVARALYHQSPRSENLFVGIDVGSIPEQLFESELFGYEKGAFTDARKEKPGR
MEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITRLGATQPIPIDIRLICATNVNIHHLVAEGTFRQDLLYRINTIELH
IPPLRERGNDVILLAEHFLSKYARKYKKDLKGINRDGKNKLHNYAWPGNVRELQHAIERAVILSESNWLRPEDFILRSVP
LRDKEPSDELNLTVLEKEAIERALRRAEGNITRAAELLGITRFTLYRKLEKFGL

Sequences:

>Translated_454_residues
MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMRTFIPDIILLDMNFKRDAISGQEGFYWLEKIKKIDPD
VVVLFMTAYSDTDKAVRAIKAGATDFIPKPWEKEKLLATLSSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPM
QAIFATVDKLKNTDANILILGENGTGKDLVARALYHQSPRSENLFVGIDVGSIPEQLFESELFGYEKGAFTDARKEKPGR
MEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITRLGATQPIPIDIRLICATNVNIHHLVAEGTFRQDLLYRINTIELH
IPPLRERGNDVILLAEHFLSKYARKYKKDLKGINRDGKNKLHNYAWPGNVRELQHAIERAVILSESNWLRPEDFILRSVP
LRDKEPSDELNLTVLEKEAIERALRRAEGNITRAAELLGITRFTLYRKLEKFGL
>Mature_454_residues
MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMRTFIPDIILLDMNFKRDAISGQEGFYWLEKIKKIDPD
VVVLFMTAYSDTDKAVRAIKAGATDFIPKPWEKEKLLATLSSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPM
QAIFATVDKLKNTDANILILGENGTGKDLVARALYHQSPRSENLFVGIDVGSIPEQLFESELFGYEKGAFTDARKEKPGR
MEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITRLGATQPIPIDIRLICATNVNIHHLVAEGTFRQDLLYRINTIELH
IPPLRERGNDVILLAEHFLSKYARKYKKDLKGINRDGKNKLHNYAWPGNVRELQHAIERAVILSESNWLRPEDFILRSVP
LRDKEPSDELNLTVLEKEAIERALRRAEGNITRAAELLGITRFTLYRKLEKFGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=38.6160714285714, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=35.9307359307359, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1790299, Length=481, Percent_Identity=34.7193347193347, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=41.25, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789087, Length=315, Percent_Identity=40.6349206349206, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788905, Length=398, Percent_Identity=33.9195979899498, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=39.2749244712991, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87081872, Length=317, Percent_Identity=38.4858044164038, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=39.1167192429022, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=37.9746835443038, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787583, Length=332, Percent_Identity=34.6385542168675, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081858, Length=284, Percent_Identity=32.0422535211268, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789828, Length=222, Percent_Identity=33.7837837837838, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51673; Mature: 51673

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMRTFIPDIILLDMNFKRD
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCC
AISGQEGFYWLEKIKKIDPDVVVLFMTAYSDTDKAVRAIKAGATDFIPKPWEKEKLLATL
CCCCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPMQAIFATVDKLKNTDANILIL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
GENGTGKDLVARALYHQSPRSENLFVGIDVGSIPEQLFESELFGYEKGAFTDARKEKPGR
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHCCCCC
MEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITRLGATQPIPIDIRLICATNVNIHHL
EEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEEE
VAEGTFRQDLLYRINTIELHIPPLRERGNDVILLAEHFLSKYARKYKKDLKGINRDGKNK
EECCCHHHHHHHEEEEEEEECCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHH
LHNYAWPGNVRELQHAIERAVILSESNWLRPEDFILRSVPLRDKEPSDELNLTVLEKEAI
CCCCCCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEHHHHH
ERALRRAEGNITRAAELLGITRFTLYRKLEKFGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMRTFIPDIILLDMNFKRD
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCC
AISGQEGFYWLEKIKKIDPDVVVLFMTAYSDTDKAVRAIKAGATDFIPKPWEKEKLLATL
CCCCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPMQAIFATVDKLKNTDANILIL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEE
GENGTGKDLVARALYHQSPRSENLFVGIDVGSIPEQLFESELFGYEKGAFTDARKEKPGR
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHCCCCC
MEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITRLGATQPIPIDIRLICATNVNIHHL
EEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEEE
VAEGTFRQDLLYRINTIELHIPPLRERGNDVILLAEHFLSKYARKYKKDLKGINRDGKNK
EECCCHHHHHHHEEEEEEEECCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHH
LHNYAWPGNVRELQHAIERAVILSESNWLRPEDFILRSVPLRDKEPSDELNLTVLEKEAI
CCCCCCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEHHHHH
ERALRRAEGNITRAAELLGITRFTLYRKLEKFGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]