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The map label for this gene is cirA [H]

Identifier: 150009989

GI number: 150009989

Start: 4147427

End: 4149610

Strand: Direct

Name: cirA [H]

Synonym: BDI_3408

Alternate gene names: 150009989

Gene position: 4147427-4149610 (Clockwise)

Preceding gene: 150009985

Following gene: 150009990

Centisome position: 86.2

GC content: 45.24

Gene sequence:

>2184_bases
ATGAAAAGAAAGTGTTTGTGCGCGGCTTTAGCTGTAAGTTGTGCGATAAACGTATCATTTGCGCAGGTACGTTTACAGGG
TAAGGTCGTGGATGAAAGTAATGAACCAATCCCGGGCGCGAATATCCGCGTGTCGGAATCCTTGAATGGTACAACCACGG
ATGCCGGCGGAAAATTTGAGCTGAACCTTCCCGATGGTAGACATCGTATTCGTGTGACTTACCTTGGCTATGAACAGGGC
GTGTATCAAACGGATCACTCGGAAAAAGATGTCGTTATTAAGCTGAAAGAAAAGTATGTGAATATCGATCAAGTGGTGGT
AACCGGTACCGGTTCGCATCGCCGCATGAGTAATTCTCCTATTCCCGTGAAAGTGCTTACGGGAAAAGACTTGAAAGAGG
CGAGCGTAACCAATTTCCAAGATGCGATGACCAAGCTGAATCCGAGTATCGTATTTATGGAAAACGGACAGGGGGCTACG
ATGAATATGAACGGATTGACAGAGAAATACGTGGTTATCTTGGAAAACGGTAAGCGTTTGGCCGGCGATGATACCTATTC
CCGTATCGATATGTCTAACGTAAAGCGGGTAGAGATCTTGAACGGGGCCGCTTCCGCTTTGTATGGTAGCGATGCGATCG
CCGGCGTTATCAATATCATCACGGATGATTCCCGTAATAAGGTGAACGTGACGAGCAATAGCCGTTATGGTAGCAAGAAC
CAATTCTTGCAGTCGGTCAATGCGGACGTGAATGTAGGGAAGTTCGGTTCATATACTTCTTATCAATATCAACGGGCCGA
TGGTTGGCAATTAAATCCCTATACGGAGAGTAAAGGCGAGTTGGTTCCTACCAATAAGCAAGCTTCCGAGGGATTTCACC
GGAACGTGATCAACCAACGTTTCACGTACGACGCTACGGATCGTTTGTCTTTTTATGTGCGTGGTACTTTCTTCGGACGT
TCCAGCGATCGTCCGATGCCGATGGATAAAGTGAATACGACCAACTATGATATGCGGAAAGAGACGTTCACTTATGGGGC
GGGCGCTCAGTACATGATTAATAAGAACTCTTATTTGAACGCTGATTATCTGTCGGACAATCATAGTACGTATAAGGATT
TCTTTGATGGAAAGAAAAGCGGAGAGAGTGATATGACGAAACGGATTCATTACCATAACTTGAATGTCAAGGGAATCTTT
CGTTTGGGCAAGTATAATAAGCTTTCGGCTGGTACAGAGTTCATTAAAGAGTTACTGAGTAGCGAGACGGATAACATAGC
GGGTAAAAGTATGTACACGACCGCGCTTTATGCGCAAGACGAGATCAATATCAATGAGCATTTCCAAGCGTACGCGGGTT
TGCGCTATATTTACCATGAGAATTTTAAGAGTTATGCGACTCCTAACGTGGCTTTGCTGTATAAGGTAGGCGGTTTTAAT
TTCCGCGGATCGTATGCGGCTGGTTTCCGTACACCTGAATTGAAAGAGCTGTATACGGAATCGGAGAAGAAAGCGTCCGG
AGCGACTCGCCTTACGATCGGTAATCCGGATCTGGACCCGGAGAAGAGCGACAATTTTACGTTGAGCGCAGAATATACGA
TGCGGTATTTCTCTTTGTCCGTGTCCGCTTTTATGAATAACGTACGTAGCATGATTAACTATAAGATGTTGGATACGGCG
GAACGGGATGCTTATAACACCGCCCATGGTACGGACTATGATGAGATACAGATGCGTGCGAATATCGATAAAGCGAAGAT
CAAAGGTATTAACGTGGCCTTCAATAGTTATCTGGGAGCGGGCTTTACCTTGAATGGTGGCTATAGTTTCATGGATGGAA
AAAACGTATATGAGGATGAGCCTTTGGATAAGACCGTTAAGCATAGTGGTACGGTAGCGGCTATGTGGTCTCATACTTGG
AATAAGTATAAGCTGAACGTGAATTTTAACGGACGTATCCAAGGGGAACGTTATTCTACTTCTTATGGATATGCGCCGAA
ATATTCCTTGTGGAATCTCAATACGAGCCATACGTTTAGAGCCGGCGATTTCTTGTTGGAACCGGGAGTAGGTATCGAGA
ACCTTTTTGATTATGTAGATGATCGTCCCTTTAATTACAATTACGCTACATTGACCCCGGGCCGTACCTATTACGTCAGC
CTTCTGGTCCGTTTCAAGCAGTAA

Upstream 100 bases:

>100_bases
GTCGTTTTCTACGAGGTAAGTCAGGAAACCTGCCAAGCGTTTTTATTGCTGTTTTTCTCGGGGTCAGGAAAGCGGAAATA
TACATAATAACAAATCGTTT

Downstream 100 bases:

>100_bases
ACTGTCACATGTCAACTATCAACTAATATAATAATGTATAGGGGATTTTTACGATCCATGTTTGTTTGTTCACTCCTGCT
TGGGTTCGCCTGTTCATTAT

Product: putative iron transport-related exported protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRVSESLNGTTTDAGGKFELNLPDGRHRIRVTYLGYEQG
VYQTDHSEKDVVIKLKEKYVNIDQVVVTGTGSHRRMSNSPIPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGAT
MNMNGLTEKYVVILENGKRLAGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVINIITDDSRNKVNVTSNSRYGSKN
QFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTESKGELVPTNKQASEGFHRNVINQRFTYDATDRLSFYVRGTFFGR
SSDRPMPMDKVNTTNYDMRKETFTYGAGAQYMINKNSYLNADYLSDNHSTYKDFFDGKKSGESDMTKRIHYHNLNVKGIF
RLGKYNKLSAGTEFIKELLSSETDNIAGKSMYTTALYAQDEININEHFQAYAGLRYIYHENFKSYATPNVALLYKVGGFN
FRGSYAAGFRTPELKELYTESEKKASGATRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLSVSAFMNNVRSMINYKMLDTA
ERDAYNTAHGTDYDEIQMRANIDKAKIKGINVAFNSYLGAGFTLNGGYSFMDGKNVYEDEPLDKTVKHSGTVAAMWSHTW
NKYKLNVNFNGRIQGERYSTSYGYAPKYSLWNLNTSHTFRAGDFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVS
LLVRFKQ

Sequences:

>Translated_727_residues
MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRVSESLNGTTTDAGGKFELNLPDGRHRIRVTYLGYEQG
VYQTDHSEKDVVIKLKEKYVNIDQVVVTGTGSHRRMSNSPIPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGAT
MNMNGLTEKYVVILENGKRLAGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVINIITDDSRNKVNVTSNSRYGSKN
QFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTESKGELVPTNKQASEGFHRNVINQRFTYDATDRLSFYVRGTFFGR
SSDRPMPMDKVNTTNYDMRKETFTYGAGAQYMINKNSYLNADYLSDNHSTYKDFFDGKKSGESDMTKRIHYHNLNVKGIF
RLGKYNKLSAGTEFIKELLSSETDNIAGKSMYTTALYAQDEININEHFQAYAGLRYIYHENFKSYATPNVALLYKVGGFN
FRGSYAAGFRTPELKELYTESEKKASGATRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLSVSAFMNNVRSMINYKMLDTA
ERDAYNTAHGTDYDEIQMRANIDKAKIKGINVAFNSYLGAGFTLNGGYSFMDGKNVYEDEPLDKTVKHSGTVAAMWSHTW
NKYKLNVNFNGRIQGERYSTSYGYAPKYSLWNLNTSHTFRAGDFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVS
LLVRFKQ
>Mature_727_residues
MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRVSESLNGTTTDAGGKFELNLPDGRHRIRVTYLGYEQG
VYQTDHSEKDVVIKLKEKYVNIDQVVVTGTGSHRRMSNSPIPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGAT
MNMNGLTEKYVVILENGKRLAGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVINIITDDSRNKVNVTSNSRYGSKN
QFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTESKGELVPTNKQASEGFHRNVINQRFTYDATDRLSFYVRGTFFGR
SSDRPMPMDKVNTTNYDMRKETFTYGAGAQYMINKNSYLNADYLSDNHSTYKDFFDGKKSGESDMTKRIHYHNLNVKGIF
RLGKYNKLSAGTEFIKELLSSETDNIAGKSMYTTALYAQDEININEHFQAYAGLRYIYHENFKSYATPNVALLYKVGGFN
FRGSYAAGFRTPELKELYTESEKKASGATRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLSVSAFMNNVRSMINYKMLDTA
ERDAYNTAHGTDYDEIQMRANIDKAKIKGINVAFNSYLGAGFTLNGGYSFMDGKNVYEDEPLDKTVKHSGTVAAMWSHTW
NKYKLNVNFNGRIQGERYSTSYGYAPKYSLWNLNTSHTFRAGDFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVS
LLVRFKQ

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=671, Percent_Identity=23.8450074515648, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1790405, Length=662, Percent_Identity=23.5649546827795, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81876; Mature: 81876

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRVSESLNGTTTDAGGKFE
CCCHHHHHHHHHHHEEEEEEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEE
LNLPDGRHRIRVTYLGYEQGVYQTDHSEKDVVIKLKEKYVNIDQVVVTGTGSHRRMSNSP
EECCCCCEEEEEEEEECCCCCEECCCCCCCEEEEEECHHCCEEEEEEECCCCCCCCCCCC
IPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGATMNMNGLTEKYVVILENGKRL
CEEEEECCCCCCHHHHCCHHHHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEEECCCEE
AGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVINIITDDSRNKVNVTSNSRYGSKN
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCHHEEEEEEEECCCCCEEEEECCCCCCCHH
QFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTESKGELVPTNKQASEGFHRNVINQR
HHHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCEECCCCHHHCCHHHHHHHCC
FTYDATDRLSFYVRGTFFGRSSDRPMPMDKVNTTNYDMRKETFTYGAGAQYMINKNSYLN
CEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEECCCCEEC
ADYLSDNHSTYKDFFDGKKSGESDMTKRIHYHNLNVKGIFRLGKYNKLSAGTEFIKELLS
CCCCCCCCCHHHHHHCCCCCCCHHHHHEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHC
SETDNIAGKSMYTTALYAQDEININEHFQAYAGLRYIYHENFKSYATPNVALLYKVGGFN
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCEEEEEECCCHHHCCCCEEEEEEECCCC
FRGSYAAGFRTPELKELYTESEKKASGATRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLS
CCCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEEHH
VSAFMNNVRSMINYKMLDTAERDAYNTAHGTDYDEIQMRANIDKAKIKGINVAFNSYLGA
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHEEEEECCCHHHEEEEEEEEECCCCC
GFTLNGGYSFMDGKNVYEDEPLDKTVKHSGTVAAMWSHTWNKYKLNVNFNGRIQGERYST
CEEECCCEEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCCEEEEEEEECCEECCCEECC
SYGYAPKYSLWNLNTSHTFRAGDFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVS
CCCCCCCEEEEECCCCCEEECCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEE
LLVRFKQ
EEEEECC
>Mature Secondary Structure
MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRVSESLNGTTTDAGGKFE
CCCHHHHHHHHHHHEEEEEEEEEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEE
LNLPDGRHRIRVTYLGYEQGVYQTDHSEKDVVIKLKEKYVNIDQVVVTGTGSHRRMSNSP
EECCCCCEEEEEEEEECCCCCEECCCCCCCEEEEEECHHCCEEEEEEECCCCCCCCCCCC
IPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGATMNMNGLTEKYVVILENGKRL
CEEEEECCCCCCHHHHCCHHHHHHHCCCEEEEEECCCCCEEECCCCCEEEEEEEECCCEE
AGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVINIITDDSRNKVNVTSNSRYGSKN
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCHHEEEEEEEECCCCCEEEEECCCCCCCHH
QFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTESKGELVPTNKQASEGFHRNVINQR
HHHHHCCCCCCCCCCCCCCCEEEECCCCCEECCCCCCCCCEECCCCHHHCCHHHHHHHCC
FTYDATDRLSFYVRGTFFGRSSDRPMPMDKVNTTNYDMRKETFTYGAGAQYMINKNSYLN
CEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEECCCCEEC
ADYLSDNHSTYKDFFDGKKSGESDMTKRIHYHNLNVKGIFRLGKYNKLSAGTEFIKELLS
CCCCCCCCCHHHHHHCCCCCCCHHHHHEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHC
SETDNIAGKSMYTTALYAQDEININEHFQAYAGLRYIYHENFKSYATPNVALLYKVGGFN
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCEEEEEECCCHHHCCCCEEEEEEECCCC
FRGSYAAGFRTPELKELYTESEKKASGATRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLS
CCCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEEHH
VSAFMNNVRSMINYKMLDTAERDAYNTAHGTDYDEIQMRANIDKAKIKGINVAFNSYLGA
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHEEEEECCCHHHEEEEEEEEECCCCC
GFTLNGGYSFMDGKNVYEDEPLDKTVKHSGTVAAMWSHTWNKYKLNVNFNGRIQGERYST
CEEECCCEEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCCEEEEEEEECCEECCCEECC
SYGYAPKYSLWNLNTSHTFRAGDFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVS
CCCCCCCEEEEECCCCCEEECCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEE
LLVRFKQ
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]