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The map label for this gene is cirA [H]

Identifier: 150009980

GI number: 150009980

Start: 4132644

End: 4134953

Strand: Direct

Name: cirA [H]

Synonym: BDI_3399

Alternate gene names: 150009980

Gene position: 4132644-4134953 (Clockwise)

Preceding gene: 150009979

Following gene: 150009982

Centisome position: 85.89

GC content: 45.97

Gene sequence:

>2310_bases
ATGAATAAATTTTTCATCTTTATACTATGCCTGTGCTGTGCCCTAACGGTAGCTCAGGCCACGGGAGAGGACCGTCTAAA
CGACTCAGACGCAAATGTTTTCGGACATGTATTGGATAAGAAAACAGGGGAGCATCTTCCCTTTATCAACGTATTGTTAA
AAGGTACCACGATCGGTACGACCACCGATAACTCGGGACATTATTTCCTGAAGAATCTGCCGGAAGGTAAATTTACGCTA
GAATATAAAGCGCTCGGGTATAAGACTATCTCTAAAGAAGTGACCCTAAAGAAAGGAAAAACCTTAGAGATTAATGTAGA
ACTGGAAGAAGACCAGATCGCCTTGGATGGCGTGGTGGTATCTGCGAATCGTGCGGAAACTTCCCGCCGGTTGGCTCCCA
CATTAGTGAATGTATTGGATGCGAAGGTTTTTACTACGACCAATGCGGTGAATTTGGCACAGGGACTAAATTTCCAACCG
GGTGTACGGGTAGAGACGAATTGCCAGAATTGCGGTTTCCAGCAAGTCCGGATCAATGGATTAGACGGACCTTATACCCA
AATACTGATTGATTCACGTCCCATATTCAGCGCTTTATCCGGCGTATATGGGCTTGAGCAAATACCGGCGAATATGATCG
AGCGGGTAGAGGTGATGCGAGGAGGGGGATCGGCACTGTTCGGCTCGTCCGCTATCGCCGGGACAATTAATATCATCACG
AAGGAGCCCTTGAGAAATTCCGGGGAATTGTCGCATACGTTAACCTCGATTGGCGGGACATCTGCTTTCGATAATAATAC
GACCCTAAATGCCTCTTTGGTATCGGAAAATGGGAAAGCGGGCTTATATCTTTTTGGCCAGAACCGTCATCGTTCCGGTT
TTGATCAGGATGGAGATGGTTTTACGGAGTTGCCTAAATTGAAGAATCAAACGGTCGGTTTCCGTTCGTACCTGAAAACG
AGTACTTATAGTAAATTGACATTCGAGTATCATCATATGAATGAATACCGCAGGGGAGGAAATCTGTTGGATCGTCCGCC
TCATGAAGCGGATATCGCCGAACAGTTGGAGCATTCGATTGATGGAGGAGGTCTGAAATTCGATCTTTTCTCCAAGGATT
ACAAACATAAATGGAGTGTTTTCACTTCTGCCCAGAATACAGACCGGGATAGTTATTACGGGACGAACCAAGATCCGAAC
GCTTACGGCAAGACTACGGACCTGACGGTTATGGCCGGTACGCAATATGCTTATAGTTTTGATAAATTCTTGTTTATGCC
ATCGGATTTGACTGCCGGTTTGGAGTATAGTTTCGATCATTTGAAAGACGAGATGATCGGGTATAATCGCTTTACGAATC
AGAAGGTGCATATCGAGAGCGCATTTTTGCAGAATGAGTGGAAAAATAAGCGATGGAGCTTCTTGATTGGCGGTCGTTTG
GATAAACATAATATGATGGATCATGTAATATTCAGCCCTCGTGCGAATATCCGTTTTAACCCGACGGAAGATATCAATAT
CCGGGCTAGTTATTCCAGTGGTTTCCGTGCCCCGCAAGCGTTCGATGAGGATATGCATATCTCGGCGGTCGGCGGAGAGG
TCGCTATGATCCAGCGTGCGAAAGATTTATCCGAGGAGAAATCGCAGAGCTTGAGTGCTTCGGTCGATTTTTACCATCGT
TTTAAGAATGGTATCCAGTTGAACTTCTTGGTGGAAGGTTTTTACACCAGCTTAAGTGATGTGTTTGTCTTGGAAGATAT
CGGGAAAGATGAGCAAGGCAATCTGATTAAGGAACGTCGTAACGGTTCCGGGGCGAAAGTGATGGGATTAACCTTGGAAG
GAAAGTCGGTGTTAACTTCATGGCTATCTTTGCAAGCGGGCGCTACTTTCCAGCGAAGCCGTTATAAAGAGGCCGAGAAA
TGGAGCGATGACGAGAATGTGCCAGCCGAGACAAAGATGTTCCGTACGCCGGATATCTATGGTTATTTTACGGCTACTCT
CACGCCTTTCAAACGTTTCACGGCTTCCCTGTCGGGAACCTATACGGGAAGTATGTTGGTGCAGCATTTGGCGGGATATA
TACCTTTGGATAAGGCGGTGGAGACTCCGGATTTCTTTGATATGAATATCAAGCTTGCGTATGAGTTCCCGCTTTACAAA
GAGCTGAAACTAGAAGTAAATGGGGGCGTGCAGAATCTGTTCAACGCTTACCAATCCGACTTTGACCAAGGTAAGAACCG
GGATTCCTCCTATATCTATGGCCCGGCTAGCCCGAGAAGTTATTTTGCCGGTGTAAAGATGAGCTTTTAA

Upstream 100 bases:

>100_bases
TATATCGTTCCCTTCCGGGGAAGACGTACGCTTCGGGCTCCTCCCATATTCTGATATTGTGAGATTAATAACATTGTATT
ACTTATCAGAATAAATTAAA

Downstream 100 bases:

>100_bases
TCATGTAATGCCCTTTGAAAAAACATGTACGTGTTTCGTGAAAAACACGTACGTGTTTCCGAAAAAAGACGTACGTGTTT
TTTTGAAGGCAAAATAAATA

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEHLPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTL
EYKALGYKTISKEVTLKKGKTLEINVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQP
GVRVETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAGLYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKT
STYSKLTFEYHHMNEYRRGGNLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDPN
AYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHIESAFLQNEWKNKRWSFLIGGRL
DKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRAPQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHR
FKNGIQLNFLVEGFYTSLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRYKEAEK
WSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYK
ELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIYGPASPRSYFAGVKMSF

Sequences:

>Translated_769_residues
MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEHLPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTL
EYKALGYKTISKEVTLKKGKTLEINVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQP
GVRVETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAGLYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKT
STYSKLTFEYHHMNEYRRGGNLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDPN
AYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHIESAFLQNEWKNKRWSFLIGGRL
DKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRAPQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHR
FKNGIQLNFLVEGFYTSLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRYKEAEK
WSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYK
ELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIYGPASPRSYFAGVKMSF
>Mature_769_residues
MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEHLPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTL
EYKALGYKTISKEVTLKKGKTLEINVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQP
GVRVETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAGLYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKT
STYSKLTFEYHHMNEYRRGGNLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDPN
AYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHIESAFLQNEWKNKRWSFLIGGRL
DKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRAPQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHR
FKNGIQLNFLVEGFYTSLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRYKEAEK
WSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYK
ELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIYGPASPRSYFAGVKMSF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=450, Percent_Identity=25.1111111111111, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790405, Length=184, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 85967; Mature: 85967

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEHLPFINVLLKGTTIGT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCEEEC
TTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEINVELEEDQIALDGVVV
CCCCCCCEEEECCCCCCEEEEEEECCCEECCCEEEECCCCEEEEEEEECCCEEEEEEEEE
SANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVRVETNCQNCGFQQVRING
ECCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEC
LDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
CCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
KEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAGLYLFGQNRHRSGFDQDGDG
CCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCC
FTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGGNLLDRPPHEADIAEQLEHSI
HHHCCHHCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
DGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDPNAYGKTTDLTVMAGTQYAYSF
CCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEC
DKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHIESAFLQNEWKNKRWSFLIGGRL
CCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCC
DKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRAPQAFDEDMHISAVGGEVAMIQRA
CCCCCHHHEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEHHHH
KDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYTSLSDVFVLEDIGKDEQGNLIKERR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHEEEEHHCCCCCCCCHHHHHC
NGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRYKEAEKWSDDENVPAETKMFRTPDIY
CCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHEEEECCCCE
GYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYK
EEEEEHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCE
ELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIYGPASPRSYFAGVKMSF
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHCCCEEECC
>Mature Secondary Structure
MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEHLPFINVLLKGTTIGT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCEEEC
TTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEINVELEEDQIALDGVVV
CCCCCCCEEEECCCCCCEEEEEEECCCEECCCEEEECCCCEEEEEEEECCCEEEEEEEEE
SANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVRVETNCQNCGFQQVRING
ECCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEC
LDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
CCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
KEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAGLYLFGQNRHRSGFDQDGDG
CCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCC
FTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGGNLLDRPPHEADIAEQLEHSI
HHHCCHHCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
DGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDPNAYGKTTDLTVMAGTQYAYSF
CCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEC
DKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHIESAFLQNEWKNKRWSFLIGGRL
CCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCC
DKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRAPQAFDEDMHISAVGGEVAMIQRA
CCCCCHHHEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEHHHH
KDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYTSLSDVFVLEDIGKDEQGNLIKERR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHEEEEHHCCCCCCCCHHHHHC
NGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRYKEAEKWSDDENVPAETKMFRTPDIY
CCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHEEEECCCCE
GYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYK
EEEEEHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCE
ELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIYGPASPRSYFAGVKMSF
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]